Results 21 to 30 of about 5,642,725 (257)

Statistical analysis plan for the Surgery for Cancer with Option of Palliative Care Expert (SCOPE) trial: a randomized controlled trial of a specialist palliative care intervention for patients undergoing surgery for cancer

Trials, 2021
Background The impact of specialist palliative care intervention in patients undergoing surgery for cancer has not been studied extensively. The SCOPE randomized controlled trial will investigate the effect of specialist palliative care intervention in ...
Onur M. Orun, Myrick C. Shinall, Aimee Hoskins, Ellis Morgan, Mohana Karlekar, Sara F. Martin, E. Wesley Ely, Rameela Raman   +7 more
doaj   +1 more source

The hypothalamic-pituitary-adrenal axis in critical illness [PDF]

, 1993
Plasma ACTH and cortisol concentrations are frequently elevated in patients in intensive care units (ICU). To examine the functional integrity of the hypothalamic-pituitary-adrenal axis during critical illness, we evaluated prospectively 53 ICU patients ...
Winkelmann, W., Allolio, B., Würth, G., Reincke, Martin   +3 more
core   +1 more source

2010 Annual Evidence Update on Critical Illness Rehabilitation [PDF]

, 2010
For this annual evidence update a detailed literature review was undertaken to retrieve any evidence published subsequent to the literature search which formed the basis for the NICE guideline.
Parker, Robert, Griffiths, John, Morris, Craig, Kishen, Roop, Gibson, Vanessa, Treacher, David   +5 more
core  

Survival is not enough: the importance of recovery after critical illness

, 2017
Recovery following an episode of critical illness can take weeks to years and is influenced pre-existing health problems as well as the nature of the critical illness episode.
Andrea P. Marshall, Marshall, Andrea P
core   +1 more source

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

Defining critical illness using immunological endotypes in patients with and without sepsis: a cohort study

Critical Care, 2023
Background Sepsis is a heterogenous syndrome with limited therapeutic options. Identifying immunological endotypes through gene expression patterns in septic patients may lead to targeted interventions.
Jeremy A. Balch, Uan-I Chen, Oliver Liesenfeld, Petr Starostik, Tyler J. Loftus, Philip A. Efron, Scott C. Brakenridge, Timothy E. Sweeney, Lyle L. Moldawer   +8 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Development and validation of a machine learning model to predict early recurrence after surgery in NSCLC patients

Scientific Reports
To develop and validate a machine learning (ML) model for predicting early recurrence (ER) within two years post-surgery in non-small cell lung cancer (NSCLC) patients.
Guo-Yong Lin, Run-Nan Chen, Shun Wu, Zhi-Sen Gao, Xiang-Qiong Guo, Xiao-Hong Zheng, Shu-Zhen Chen   +6 more
doaj   +1 more source

Participant retention practices in longitudinal clinical research studies with high retention rates

BMC Medical Research Methodology, 2017
Background There is a need for improving cohort retention in longitudinal studies. Our objective was to identify cohort retention strategies and implementation approaches used in studies with high retention rates.
Martha Abshire, Victor D. Dinglas, Maan Isabella A. Cajita, Michelle N. Eakin, Dale M. Needham, Cheryl Dennison Himmelfarb   +5 more
doaj   +1 more source

Clinical review: special populations - critical illness and pregnancy

, 2011
Critical illness is an uncommon but potentially devastating complication of pregnancy. The majority of pregnancy-related critical care admissions occur postpartum. Antenatally, the pregnant patient is more likely to be admitted with diseases non-specific
Neligan, Patrick J, Laffey, John G
core   +1 more source