Results 21 to 30 of about 5,402,059 (303)

Antimicrobial exposure and the risk of delirium in critically ill patients

Critical Care, 2018
Background Prior retrospective cross-sectional work has associated antimicrobials with a non-specific phrase: encephalopathy without seizures. The purpose of this study is to determine whether different classes of antimicrobials have differential ...
Jessica J. Grahl, Joanna L. Stollings, Shayan Rakhit, Anna K. Person, Li Wang, Jennifer L. Thompson, Pratik P. Pandharipande, E. Wesley Ely, Mayur B. Patel   +8 more
doaj   +1 more source

Critical illness-induced dysglycaemia : diabetes and beyond [PDF]

, 2010
Type 2 diabetes has reached epidemic proportions in many parts of the world. The disease is projected to continue to increase and double within the foreseeable future.
Ann M Sheehy, Sheehy, Ann M., Vincent, J.-L. (Jean-Louis), Fang Smith, Vincent, J. L., Jean-Louis Vincent, Coursin, Douglas B., Smith, F. Gao (Fang Gao), Sheehy, A.M. (Ann M.), Douglas B Coursin, Smith, F.G. (Fang G.), Coursin, D.B. (Douglas B.)   +11 more
core   +1 more source

Long-Term Outcomes: Sleep in Survivors of Critical Illness

, 2023
Critical care survivors frequently experience cognitive, physical, and psychological sequelae (often labelled post-intensive care syndrome) that affect their wellbeing and quality of life.
McKinley, S, Pilowsky, J, Stedman, W, Elliott, R   +3 more
core   +1 more source

Influence of Limonin on Malignant Biological Behavior of Non-small Cell Lung Cancer Cells by Regulating JAK2/STAT3 Signaling Pathway

Zhongliu Fangzhi Yanjiu, 2023
Objective To investigate the influence of limonin on the malignant biological behavior of non-small cell lung cancer (NSCLC) cells by regulating the protein tyrosine kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) signaling ...
HU Huijie, ZHENG Xiaolu, LEI Lifeng
doaj   +1 more source

COVID-19: ICU delirium management during SARS-CoV-2 pandemic

Critical Care, 2020
The novel coronavirus, SARS-CoV-2-causing Coronavirus Disease 19 (COVID-19), emerged as a public health threat in December 2019 and was declared a pandemic by the World Health Organization in March 2020.
Katarzyna Kotfis, Shawniqua Williams Roberson, Jo Ellen Wilson, Wojciech Dabrowski, Brenda T. Pun, E. Wesley Ely   +5 more
doaj   +1 more source

Effectiveness of Convalescent Plasma Therapy in Treating COVID-19: an Evidence-based Case Report

Acta Medica Indonesiana, 2022
Background: Convalescent plasma is a potentially beneficial, tolerable, and available additional treatment option for COVID-19. This study aims to evaluate whether the administration of convalescent plasma therapy leads to improved clinical outcomes in ...
Mira Yulianti, Christian Johan, Gurmeet Singh, Eric Daniel Tenda, Herikurniawan Herikurniawan, I Putu Eka Krisnha Wijaya   +5 more
doaj   +2 more sources

Inhibition of Murine Pulmonary Microvascular Endothelial Cell Apoptosis Promotes Recovery of Barrier Function under Septic Conditions

Mediators of Inflammation, 2017
Sepsis is characterized by injury of the pulmonary microvasculature and the pulmonary microvascular endothelial cells (PMVEC), leading to barrier dysfunction and acute respiratory distress syndrome (ARDS).
Lefeng Wang, Sanjay Mehta, Michael Brock, Sean E. Gill   +3 more
doaj   +1 more source

The Intestinal Microbiome after Traumatic Injury

Microorganisms, 2023
The intestinal microbiome plays a critical role in host immune function and homeostasis. Patients suffering from—as well as models representing—multiple traumatic injuries, isolated organ system trauma, and various severities of traumatic injury have ...
Jennifer A. Munley, Stacey L. Kirkpatrick, Gwendolyn S. Gillies, Letitia E. Bible, Philip A. Efron, Ravinder Nagpal, Alicia M. Mohr   +6 more
doaj   +1 more source

A Proteinase 3 Contribution to Juvenile Idiopathic Arthritis-Associated Cartilage Damage

Pathophysiology, 2021
A full understanding of the molecular mechanisms implicated in the etiopathogenesis of juvenile idiopathic arthritis (JIA) is lacking. A critical role for leukocyte proteolytic activity (e.g., elastase and cathepsin G) has been proposed.
Eric K. Patterson, Nicolas Vanin Moreno, Douglas D. Fraser, Gediminas Cepinskas, Takaya Iida, Roberta A. Berard   +5 more
doaj   +1 more source

Procalcitonin in Critical Illness

Critical Care and Resuscitation, 2001
To detail the biology and diagnostic usefulness of serum procalcitonin in critical illness.A review of articles published in peer reviewed journals from 1990 to 2001 and identified through a MEDLINE search on procalcitonin.Procalcitonin (PCT) is a prohormone of calcitonin.
E, O'Connor, B, Venkatesh, J, Lipman, C, Mashongonyika, J, Hall   +4 more
openaire   +2 more sources