Results 11 to 20 of about 5,402,059 (303)

Protocol for a multicentre, randomised controlled trial of computerised cognitive rehabilitation in survivors of critical illness: the RETURN-III study [PDF]

BMJ Open
Introduction Cognitive impairment after critical illness is a common occurrence that has a profound impact on millions of people worldwide each year.
E Wesley Ely, Robert A Greevy, Jacob Lee, Matthew F Mart, Amy Kiehl, Edward Tang Qian, Mark L Rolfsen, Mayur B Patel, Jim C Jackson, Rameela Raman, Tyler J Murphy, Caroline I Birdrow, Natalie A Mastalerz, Megan J Wurtz, Jordan Thompson, Erika L Rivera, Mina F Nordness, Erin M Collar, Anil J Trindade, Alexander Dragnich   +19 more
doaj   +2 more sources

Critical care use during the course of serious illness. [PDF]

, 2004
Despite its expense and importance, it is unknown how common critical care use is. We describe longitudinal patterns of critical care use among a nationally representative cohort of elderly patients monitored from the onset of common serious illnesses. A
Iwashyna, Theodore J.
core   +7 more sources

Redefining critical illness [PDF]

Nature Medicine, 2022
Research and practice in critical care medicine have long been defined by syndromes, which, despite being clinically recognizable entities, are, in fact, loose amalgams of heterogeneous states that may respond differently to therapy. Mounting translational evidence-supported by research on respiratory failure due to severe acute respiratory syndrome ...
Maslove, David M, Tang, Benjamin, Shankar-Hari, Manu, Lawler, Patrick R, Angus, Derek C, Baillie, J Kenneth, Baron, Rebecca M, Bauer, Michael, Buchman, Timothy G, Calfee, Carolyn S, Dos Santos, Claudia C, Giamarellos-Bourboulis, Evangelos J, Gordon, Anthony C, Kellum, John A, Knight, Julian C, Leligdowicz, Aleksandra, McAuley, Daniel F, McLean, Anthony S, Menon, David K, Meyer, Nuala J, Moldawer, Lyle L, Reddy, Kiran, Reilly, John P, Russell, James A, Sevransky, Jonathan E, Seymour, Christopher W, Shapiro, Nathan I, Singer, Mervyn, Summers, Charlotte, Sweeney, Timothy E, Thompson, B Taylor, van der Poll, Tom, Venkatesh, Balasubramanian, Walley, Keith R, Walsh, Timothy S, Ware, Lorraine B, Wong, Hector R, Zador, Zsolt E, Marshall, John C   +38 more
openaire   +8 more sources

Expert Consensus on the Application of Ulinastatin in Common Clinical Critical Illness [PDF]

, 2023
Ulinastatin is mainly applied in the treatment of acute pancreatitis, but also in other common clinical critical illnesses such as shock, sepsis, evere pneumonia, cute respiratory distress syndrome, several acute poisoning, severe heat stroke, severe ...
Expert group of expert consensus on the application of ulinastatin in common clinical critical illness
core   +2 more sources

Thrombocytopaenia in the critically ill [PDF]

Tidsskrift for Den norske legeforening, 2021
publishedVersion
Håkon Reikvam, Reidar Kvåle, Einar Kristoffersen, Knut Anders Mosevoll, Øyvind Bruserud   +4 more
openaire   +4 more sources

Effect of propranolol and clonidine after severe traumatic brain injury: a pilot randomized clinical trial

Critical Care, 2023
Objective To evaluate the safety, feasibility, and efficacy of combined adrenergic blockade with propranolol and clonidine in patients with severe traumatic brain injury (TBI).
Mina F. Nordness, Amelia W. Maiga, Laura D. Wilson, Tatsuki Koyama, Erika L. Rivera, Shayan Rakhit, Michael de Riesthal, Cari L. Motuzas, Madison R. Cook, Deepak K. Gupta, James C. Jackson, Shawniqua Williams Roberson, William J. Meurer, Roger J. Lewis, Geoffrey T. Manley, Pratik P. Pandharipande, Mayur B. Patel   +16 more
doaj   +1 more source

Immunomodulation in the critically ill [PDF]

British Journal of Anaesthesia, 2009
Immunotherapy in the critically ill is an appealing notion because of the apparent abnormal immune and inflammatory responses seen in so many patients. The administration of a medication that could alter immune responses and decrease mortality in patients with sepsis could represent a 'magic bullet'.
Webster, N.R., Galley, H.F.
openaire   +2 more sources

Instruments Assessing Cognitive Impairment in Survivors of Critical Illness and Reporting of Race Norms: A Systematic Review

Critical Care Explorations, 2022
OBJECTIVE:. To conduct a systematic review to summarize cognitive instruments being used in long-term outcome studies of survivors of adult critical illness, as well as evaluate whether these measures are reported as using patient demographic norms ...
Rameela Raman, PhD, Spencer J. DesAutels, MLIS, Alana M. Lauck, MS, Alexa M. Scher, BA, Rachel L. Walden, MLIS, Amy L. Kiehl, MA, Erin M. Collar, MPH, E. Wesley Ely, MD, MPH, Pratik P. Pandharipande, MD, MSCI, James C. Jackson, PsyD   +9 more
doaj   +1 more source

Heterogeneity in design and analysis of ICU delirium randomized trials: a systematic review

Trials, 2021
Background There is a growing number of randomized controlled trials (RCTs) evaluating interventions to prevent or treat delirium in the intensive care unit (ICU).
Elizabeth Colantuoni, Mounica Koneru, Narjes Akhlaghi, Ximin Li, Mohamed D. Hashem, Victor D. Dinglas, Karin J. Neufeld, Michael O. Harhay, Dale M. Needham   +8 more
doaj   +1 more source

Voluntary running exercise protects against sepsis-induced early inflammatory and pro-coagulant responses in aged mice

Critical Care, 2017
Background Despite many animal studies and clinical trials, mortality in sepsis remains high. This may be due to the fact that most experimental studies of sepsis employ young animals, whereas the majority of septic patients are elderly (60 − 70 years ...
Karel Tyml, Scott Swarbreck, Cynthia Pape, Dan Secor, James Koropatnick, Qingping Feng, Ruud A. W. Veldhuizen, Sean E. Gill   +7 more
doaj   +1 more source