Results 41 to 50 of about 5,402,059 (303)

Participant retention practices in longitudinal clinical research studies with high retention rates

BMC Medical Research Methodology, 2017
Background There is a need for improving cohort retention in longitudinal studies. Our objective was to identify cohort retention strategies and implementation approaches used in studies with high retention rates.
Martha Abshire, Victor D. Dinglas, Maan Isabella A. Cajita, Michelle N. Eakin, Dale M. Needham, Cheryl Dennison Himmelfarb   +5 more
doaj   +1 more source

scRNA-seq revealed high stemness epithelial malignant cell clusters and prognostic models of lung adenocarcinoma

Scientific Reports
Lung adenocarcinoma (LUAD) is one of the sole causes of death in lung cancer patients. This study combined with single-cell RNA-seq analysis to identify tumor stem-related prognostic models to predict the prognosis of lung adenocarcinoma, chemotherapy ...
GuoYong Lin, ZhiSen Gao, Shun Wu, JianPing Zheng, XiangQiong Guo, XiaoHong Zheng, RunNan Chen   +6 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

COVID-19 Associated Pulmonary Aspergillosis: A Case Series

Acta Medica Indonesiana, 2022
Coronavirus disease 2019 (COVID-19) has been a worldwide pandemic with several problems, one of which is the lack of definitive treatment. COVID-19-associated pulmonary aspergillosis (CAPA), the presence of invasive pulmonary aspergillosis (IPA) in COVID-
Mira Yulianti, Christian Johan, Eric Daniel Tenda, Gurmeet Singh, Herikurniawan Herikurniawan, I Putu Eka Krisnha Wijaya   +5 more
doaj   +2 more sources

Preterm birth skews the developmental trajectory of myeloid-derived suppressor cells in the first 48 hours of life: single-cell transcriptomics and inferred intercellular communication

Molecular Medicine
Background Prematurity is a leading cause of neonatal and childhood mortality, with infections driving early deaths. Innate immunity provides frontline defense after birth and is shaped in part by myeloid-derived suppressor cells (MDSCs).
Miguel Hernández-Ríos, Jaimar Rincon, Leandro Balzano-Nogueira, Valerie Polcz, Dayuan Wang, Whitman Wiggins, Christine Rodhouse, Athina Yoham, Feifei Xiao, Ricardo Ungaro, Marvin Dirain, Lyle Moldawer, Robert Maile, Guoshuai Cai, Philip Efron, Shawn Larson   +15 more
doaj   +1 more source

Association between cholinesterase activity and critical illness brain dysfunction

Critical Care, 2022
Background Delirium is a frequent manifestation of acute brain dysfunction and is associated with cognitive impairment. The hypothesized mechanism of brain dysfunction during critical illness is centered on neuroinflammation, regulated in part by the ...
Christopher G. Hughes, Christina S. Boncyk, Benjamin Fedeles, Pratik P. Pandharipande, Wencong Chen, Mayur B. Patel, Nathan E. Brummel, James C. Jackson, Rameela Raman, E. Wesley Ely, Timothy D. Girard   +10 more
doaj   +1 more source

A Transcriptomic Severity Metric That Predicts Clinical Outcomes in Critically Ill Surgical Sepsis Patients

Critical Care Explorations, 2021
OBJECTIVES:. Clinically deployable methods for the rapid and accurate prediction of sepsis severity that could elicit a meaningful change in clinical practice are currently lacking.
Scott C. Brakenridge, MD, Petr Starostik, MD, Gabriella Ghita, PhD, Uros Midic, PhD, Dijoia Darden, MD, Brittany Fenner, MD, James Wacker, MS, Philip A. Efron, MD, Oliver Liesenfeld, MD, Timothy E. Sweeney, MD, PhD, Lyle L. Moldawer, PhD   +10 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Continuous-flow ventilation with VENTIJET in moderate ARDS: a pilot safety and feasibility study

Intensive Care Medicine Experimental
Background Acute respiratory distress syndrome (ARDS) remains associated with high mortality and ventilator-induced lung injury. Continuous-flow ventilation (CFV) may reduce cyclic strain, but faced technical limitations. VENTIJET is a novel nozzle-based
Lucía Picazo Moreno, Andrea Castellví-Font, Maria Acer Puig, Carles Camañes Mayordomo, Cristina Soriano Rodríguez, Joan Ramon Masclans Enviz, Francisco José Parrilla-Gómez   +6 more
doaj   +1 more source

Global, regional, and national cardiovascular disease burden attributable to smoking from 1990 to 2021: Findings from the GBD 2021 Study

Tobacco Induced Diseases
Introduction Smoking poses a serious threat to cardiovascular health. The aim of the study is to evaluate the global, regional, and national burden of smokingattributable cardiovascular disease (CVD) and set priorities for future tobacco control ...
Shuaijie Zhu, Jian Gao, Liangliang Zhang, Wanguo Dong, Wei Shi, Heng Guo, Xiaoyu Zhang, Tianfeng Hua, Min Yang   +8 more
doaj   +1 more source