Results 51 to 60 of about 5,642,725 (257)

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Protocol for a multicentre, randomised controlled trial of computerised cognitive rehabilitation in survivors of critical illness: the RETURN-III study

BMJ Open
Introduction Cognitive impairment after critical illness is a common occurrence that has a profound impact on millions of people worldwide each year.
E Wesley Ely, Robert A Greevy, Jacob Lee, Matthew F Mart, Amy Kiehl, Edward Tang Qian, Mark L Rolfsen, Mayur B Patel, Jim C Jackson, Rameela Raman, Tyler J Murphy, Caroline I Birdrow, Natalie A Mastalerz, Megan J Wurtz, Jordan Thompson, Erika L Rivera, Mina F Nordness, Erin M Collar, Anil J Trindade, Alexander Dragnich   +19 more
doaj   +1 more source

Critical illness myopathy, critical illness neuropathy, or both?

, 2003
Critical illness polyneuropathy and myopathy often ...
Latronico N., LATRONICO, Nicola
core   +1 more source

Pharmacological Therapy for the Prevention and Treatment of Weakness After Critical Illness: A Systematic Review. [PDF]

, 2016
OBJECTIVES: ICU-acquired weakness is a common complication of critical illness and can have significant effects upon functional status and quality of life.
Stephen J. Brett, Shepherd, SJ, Enhancing Rehabilitation After Critical Illness Programme Study Investigators, Shepherd, Stephen, Brett, SJ, Richard Newman, David M. Griffith, ?, ?, Griffith, David; id_orcid, Brett, Stephen, Griffith, DM, Newman, R, Newman, Richard, Stephen J. Shepherd   +13 more
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Factors associated with missed assessments in a 2-year longitudinal study of acute respiratory distress syndrome survivors

BMC Medical Research Methodology, 2018
Background To evaluate participant-related variables associated with missing assessment(s) at follow-up visits during a longitudinal research study. Methods This is a prospective, longitudinal, multi-site study of 196 acute respiratory distress syndrome (
Sara E. Heins, Amy W. Wozniak, Elizabeth Colantuoni, Kristin A. Sepulveda, Pedro A. Mendez-Tellez, Cheryl Dennison-Himmelfarb, Dale M. Needham, Victor D. Dinglas   +7 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Long non-coding RNAs in neurodegenerative diseases – Molecular mechanisms, liquid biopsy biomarkers, and therapeutic targets: A review

Biomolecules & Biomedicine
Neurodegenerative diseases (NDDs), such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and Huntington's disease (HD), are age-related disorders characterized by progressive neuronal loss, cognitive decline ...
Yipeng Cheng, Mingyue Qiu, Zhijie Yu, Xu Tang, Jingjing Zhang   +4 more
doaj   +1 more source

Monitoring and optimising outcomes of survivors of critical illness [PDF]

, 2015
Recovery after critical illness can be protracted and challenging. Compromise of physical, psychological, cognitive and social function is experienced by some patients and may persist for a number of years.
Marshall, A. P., Aitken, L. M., Marshall, Andrea P, Aitken, Leanne M   +3 more
core   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source