Results 1 to 10 of about 6,755,416 (402)

Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19

New England Journal of Medicine, 2021
Background: The efficacy of interleukin-6 receptor antagonists in critically ill patients with coronavirus disease 2019 (Covid-19) is unclear. Methods: We evaluated tocilizumab and sarilumab in an ongoing international, multifactorial, adaptive platform ...
A. Gordon, P. Mouncey, Farah Al-Beidh, K. Rowan, A. Nichol, Y. Arabi, D. Annane, A. Beane, Wilma van Bentum-Puijk, L. Berry, Zahra Bhimani, M. Bonten, C. Bradbury, F. Brunkhorst, Adrian Buzgau, A. Cheng, M. Detry, E. J. Duffy, L. Estcourt, M. Fitzgerald, H. Goossens, R. Haniffa, A. Higgins, T. Hills, Christopher M. Horvat, F. Lamontagne, P. Lawler, H. Leavis, K. Linstrum, E. Litton, E. Lorenzi, J. Marshall, F. Mayr, D. McAuley, A. McGlothlin, S. McGuinness, B. McVerry, S. Montgomery, S. Morpeth, S. Murthy, Katrina Orr, R. Parke, Jane C. Parker, A. Patanwala, V. Pettilä, E. Rademaker, Marlene S. Santos, Christina T. Saunders, C. Seymour, M. Shankar-Hari, W. Sligl, A. Turgeon, Anne M Turner, F. L. van de Veerdonk, R. Zarychanski, Cameron Green, R. Lewis, D. Angus, C. McArthur, S. Berry, S. Webb, L. Derde   +61 more
semanticscholar   +3 more sources

Unveiling the Problems of Critically Ill Children in Indonesia: A Narrative Review [PDF]

Journal of Pediatric Emergency and Intensive Care Medicine
The mortality rate of children in Indonesia is still high when compared to that in developed countries. The mortality rate of children in Indonesia remains high due to various factors.
Kurniawan Taufiq Kadafi, Saptadi Yuliarto, Charity Monica, Takhta Khalasha   +3 more
doaj   +2 more sources

Taurine in Septic Critically Ill Patients: Plasma versus Blood [PDF]

Advanced Pharmaceutical Bulletin, 2023
Purpose: Sepsis and systemic inflammatory response syndrome (SIRS) encompass various problems throughout the body, and two of its major problems are the creation of oxidative substances in the body and decrease of the body’s antioxidant capacity to deal ...
Ata Mahmoodpoor, Afsaneh Farjami, Niloufar Farzan, Hamed Hamishehkar, Parina Asgharian, Sarvin Sanaie, Kamran Shadvar, Farnaz Naeimzadeh, Hadi Hamishehkar   +8 more
doaj   +1 more source

Redefining critical illness

Nature Medicine, 2022
Research and practice in critical care medicine have long been defined by syndromes, which, despite being clinically recognizable entities, are, in fact, loose amalgams of heterogeneous states that may respond differently to therapy. Mounting translational evidence-supported by research on respiratory failure due to severe acute respiratory syndrome ...
Maslove, David M, Tang, Benjamin, Shankar-Hari, Manu, Lawler, Patrick R, Angus, Derek C, Baillie, J Kenneth, Baron, Rebecca M, Bauer, Michael, Buchman, Timothy G, Calfee, Carolyn S, Dos Santos, Claudia C, Giamarellos-Bourboulis, Evangelos J, Gordon, Anthony C, Kellum, John A, Knight, Julian C, Leligdowicz, Aleksandra, McAuley, Daniel F, McLean, Anthony S, Menon, David K, Meyer, Nuala J, Moldawer, Lyle L, Reddy, Kiran, Reilly, John P, Russell, James A, Sevransky, Jonathan E, Seymour, Christopher W, Shapiro, Nathan I, Singer, Mervyn, Summers, Charlotte, Sweeney, Timothy E, Thompson, B Taylor, van der Poll, Tom, Venkatesh, Balasubramanian, Walley, Keith R, Walsh, Timothy S, Ware, Lorraine B, Wong, Hector R, Zador, Zsolt E, Marshall, John C   +38 more
openaire   +10 more sources

Extreme hypernatremia in a critically ill patient with feeding-jejunostomy: a case report.

Critical Care Innovations, 2023
Hypernatremia is a frequent and potentially life-threatening condition in hospitalized patients. It is a disorder of water metabolism and is usually defined as a plasma sodium concentration above 145 mEq/L.
Amarjeet Kumar, Kunal Singh, Poonam Kumari, Haasith Dara , Gayatri Sagdeo   +4 more
doaj   +1 more source

Effect of hyperglycaemia on outcome of critically ill patients with and without diabetes mellitus admitted to medical intensive care unit

Journal of Clinical and Scientific Research, 2022
Background: Hyperglycaemia among critically ill patients is associated with nosocomial infections, multi-organ dysfunction and prolonged hospitalisation.
T Sowjanya Lakshmi, D T Katyarmal, Sameeraja Vaddera, Suresh Vaikkakara, K V S. Sarma   +4 more
doaj   +1 more source

Video versus Direct Laryngoscopy for Tracheal Intubation of Critically Ill Adults.

New England Journal of Medicine, 2023
BACKGROUND Whether video laryngoscopy as compared with direct laryngoscopy increases the likelihood of successful tracheal intubation on the first attempt among critically ill adults is uncertain. METHODS In a multicenter, randomized trial conducted at
M. Prekker, B. Driver, S. Trent, D. Resnick-Ault, K. Seitz, D. Russell, J. Gaillard, Andrew J. Latimer, S. Ghamande, K. Gibbs, D. Vonderhaar, M. Whitson, Christopher R. Barnes, J. Walco, I. Douglas, V. Krishnamoorthy, A. Dagan, Jill J. Bastman, B. D. Lloyd, S. Gandotra, Jordan K Goranson, S. Mitchell, H. White, J. Palakshappa, A. Espinera, D. Page, A. Joffe, Sydney J Hansen, C. Hughes, Tobias George, J. T. Herbert, N. Shapiro, S. Schauer, B. Long, B. Imhoff, Li Wang, J. Rhoads, K. Womack, D. Janz, W. Self, T. Rice, A. Ginde, J. Casey, M. Semler   +43 more
semanticscholar   +1 more source

Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study

The Lancet Respiratory Medicine, 2020
Background An ongoing outbreak of pneumonia associated with the severe acute respiratory coronavirus 2 (SARS-CoV-2) started in December, 2019, in Wuhan, China. Information about critically ill patients with SARS-CoV-2 infection is scarce.
Xiaobo Yang, Yuan Yu, Jiqian Xu, Huaqing Shu, Jia’an Xia, Hong Liu, Yongran Wu, Lu Zhang, Zhui Yu, Minghao Fang, Ting Yu, Yaxin Wang, Shangwen Pan, X. Zou, Shi-ying Yuan, Y. Shang   +15 more
semanticscholar   +1 more source

Incidence of thrombotic complications in critically ill ICU patients with COVID-19

Thrombosis Research, 2020
Introduction COVID-19 may predispose to both venous and arterial thromboembolism due to excessive inflammation, hypoxia, immobilisation and diffuse intravascular coagulation. Reports on the incidence of thrombotic complications are however not available.
F. Klok, M. Kruip, N. Meer, M. Arbous, D. Gommers, K. Kant, F. Kaptein, J. Paassen, M. Stals, M. Huisman, H. Endeman   +10 more
semanticscholar   +1 more source

Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19

New England Journal of Medicine, 2021
Background Thrombosis and inflammation may contribute to morbidity and mortality among patients with coronavirus disease 2019 (Covid-19). We hypothesized that therapeutic-dose anticoagulation would improve outcomes in critically ill patients with Covid ...
E. Goligher, C. Bradbury, B. McVerry, P. Lawler, J. Berger, M. Gong, M. Carrier, H. Reynolds, Ananda K Kumar, A. Turgeon, L. Kornblith, S. Kahn, J. Marshall, Keri S. Kim, Brett L. Houston, L. Derde, M. Cushman, T. Tritschler, D. Angus, L. C. Godoy, Z. McQuilten, B. Kirwan, M. Farkouh, M. Brooks, R. Lewis, L. Berry, E. Lorenzi, A. Gordon, S. Berry, C. McArthur, M. Neal, J. Hochman, S. Webb, R. Zarychanski, T. Ahuja, Farah Al-Beidh, D. Annane, Y. Arabi, Diptesh Aryal, Lisa Baumann Kreuziger, A. Beane, Zahra Bhimani, S. Bihari, H. Billett, Lindsay Bond, M. Bonten, F. Brunkhorst, M. Buxton, Adrian Buzgau, L. Castellucci, S. Chekuri, J. Chen, A. Cheng, Tamta Chkhikvadze, B. Coiffard, Aira Contreras, Todd W. Costantini, S. de Brouwer, M. Detry, A. Duggal, V. Džavík, M. Effron, H. Eng, J. Escobedo, L. Estcourt, Brendan M. Everett, D. Fergusson, M. Fitzgerald, R. Fowler, J. Froess, Zhuxuan Fu, J. Galanaud, B. Galen, S. Gandotra, T. Girard, A. Goodman, H. Goossens, Cameron Green, Y. Greenstein, P. Gross, R. Haniffa, Sheila M. Hegde, C. Hendrickson, A. Higgins, A. Hindenburg, A. Hope, J. Horowitz, Christopher M. Horvat, David T. Huang, Kristin M. Hudock, B. Hunt, M. Husain, R. Hyzy, J. Jacobson, Devachandran Jayakumar, N. Keller, Akram Khan, Yuri Kim, Andrei L. Kindzelski, A. King, M. Knudson, Aaron E. Kornblith, M. Kutcher, M. Laffan, F. Lamontagne, G. Le Gal, Christine M. Leeper, E. Leifer, G. Lim, F. Gallego Lima, K. Linstrum, E. Litton, J. López-Sendón, S. Lother, N. Marten, Andréa Saud Marinez, Mary Martinez, E. Mateos Garcia, Stavroula Mavromichalis, D. McAuley, E. McDonald, A. McGlothlin, S. McGuinness, S. Middeldorp, S. Montgomery, P. Mouncey, S. Murthy, G. Nair, Rahul R. Nair, A. Nichol, J. Nicolau, Brenda Nunez-Garcia, John J. Park, P. Park, R. Parke, Jane C. Parker, S. Parnia, J. Paul, M. Pompilio, J. Quigley, R. Rosenson, N. Rost, K. Rowan, F. O. Santos, Marlene S. Santos, M. O. Santos, L. Satterwhite, Christina T. Saunders, J. Schreiber, R. Schutgens, C. Seymour, D. Siegal, De Silva, A. Singhal, A. Slutsky, Dayna Solvason, S. Stanworth, Anne M Turner, Wilma van Bentum-Puijk, F. L. van de Veerdonk, S. van Diepen, G. Vázquez-Grande, Lana Wahid, Vanessa Wareham, R. Widmer, Jennifer G. Wilson, E. Yuriditsky, Yongqi Zhong   +167 more
semanticscholar   +1 more source