Results 151 to 160 of about 1,570,861 (237)

Anorectal Complications in Acute Leukaemia: <i>A retrospective analysis of clinical characteristics, management and outcomes in a tertiary care setting in Oman</i>. [PDF]

Sultan Qaboos Univ Med J
Al Himali N, Al Khabori M, Al Huneini M.
europepmc   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

Advanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li, Juan Cao, Yu‐Lin Wang, Yu‐Han Fan, Jia‐Qi Xu, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +7 more
wiley   +1 more source

B/T Mixed Phenotype Acute Leukaemia Harbouring <i>NUP98::BPTF</i> Fusion. [PDF]

EJHaem
Nguyen VT, Han L, Xu J, Cantu M, Fuda F, John S, Slone T, Chen W.   +7 more
europepmc   +1 more source

p53 as a unique target of action of cisplatin in acute leukaemia cells. [PDF]

J Cell Mol Med, 2022
Kumar S, Tchounwou PB.
europepmc   +1 more source

SIRT5‐Mediated Desuccinylation of ACAA2 Protects Against Calcium Oxalate‐Induced Kidney Injury by Regulating Fatty Acid Oxidation to Suppress Mitochondrial Oxidative Injury and Ferroptosis

Advanced Science, EarlyView.
The SIRT5/ACAA2 axis maintains lipid metabolic homeostasis in RTECs by promoting ACAA2 desuccinylation and preserving its stability and enzymatic activity, thereby sustaining FAO and limiting PUFA and PUFA‐containing phospholipid accumulation. Under CaOx stress, SIRT5 downregulation impairs FAO, promotes oxidative stress and ferroptosis, and enhances ...
Qinhong Jiang, Caitao Dong, Yuchen Liu, Yuanquan Lou, Wenlong Lin, Sheng Li, Ziqi He   +6 more
wiley   +1 more source

Factors influencing sense of coherence in caregivers of children with acute leukaemia. [PDF]

BMC Nurs
Liu CY, Wang F, Lv HT, Ni ZH.
europepmc   +1 more source

Bilateral massive nephromegaly as a presenting manifestation of mixed phenotype acute leukaemia. [PDF]

BMJ Case Rep, 2022
Shaji A, Rajarajen AP, Sethi J, Joshi R.
europepmc   +1 more source

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

Acute Lymphoblastic Leukaemia presenting as Juvenile Idiopathic Arthritis in a Nigerian boy

Nigerian Journal of Paediatrics
Background: Acute Lymphoblastic Leukaemia in children commonly presents with osteo articular manifestations that may mimic Juvenile Idiopathic Arthritis.
Onubogu UC , Okoh BAN, Eke G , Joboy-okei EA   +3 more
doaj  

Understanding the causes of high mortality among adult acute leukaemia patients in Armenia. [PDF]

Ecancermedicalscience
Voskanyan A, Harutyunyan L, Ivanyan A, Movsisyan A, Ghahramanyan N, Sahakyan L, Hovsepyan S, Danielyan S, Grigoryan H, Tamamyan G.   +9 more
europepmc   +1 more source