Results 1 to 10 of about 253,535 (214)
Time to haematologist visit and non-haematological referral from primary health care during blood cancer diagnosis – findings from a large national survey in Australia [PDF]
BMC CancerBackground Blood cancers are the third most common cancer in Australia. However, little is known about their diagnostic pathway in the Australian context.
Mohammad Radwanur Talukder +3 more
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Cancer Cell International, 2023 Background Development of precision medicine requires the identification of easily detectable and druggable biomarkers. Despite recent targeted drug approvals, prognosis of acute myeloid leukemia (AML) patients needs to be greatly improved, as relapse ...
Laia Cuesta-Casanovas +7 more
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PTEN/PI3K/Akt pathway alters sensitivity of T-cell acute lymphoblastic leukemia to l-asparaginase
Scientific Reports, 2022 Childhood T-cell acute lymphoblastic leukemia (T-ALL) still remains a therapeutic challenge due to relapses which are resistant to further treatment. l-asparaginase (ASNase) is a key therapy component in pediatric T-ALL and lower sensitivity of leukemia ...
Katerina Hlozkova +10 more
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Epigenetics, 2023 DNA methylation, one of the best characterized epigenetic marks in the human genome, plays a pivotal role in gene transcription regulation and other biological processes in humans.
Aleix Noguera-Castells +3 more
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Leukaemia cutis with chronic myelomonocytic leukaemia [PDF]
British Journal of Haematology, 2009 A 95-year-old woman presented with a 4-week history of lethargy, and gradual onset of a florid eruption of asymptomatic red cutaneous nodules on her trunk and legs (top). A full blood count showed: haemoglobin concentration 100 g/l, white blood cell count 59 · 10/l, platelet count 75 · 10/l, neutrophils 40 · 10/l, monocytes 15 · 10/l, basophils 0AE4 ...
Shameem, Mahmood +3 more
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Low input capture Hi-C (liCHi-C) identifies promoter-enhancer interactions at high-resolution
Nature Communications, 2023 Here the authors present the low input capture Hi-C (liCHi-C) method, a cost-effective, flexible method to map and robustly compare promoter interactomes at high resolution.
Laureano Tomás-Daza +15 more
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Validation of a DNA methylation microarray for 285,000 CpG sites in the mouse genome
Epigenetics, 2022 Mouse has been extensively used as a model organism in many studies to characterize biological pathways and drug effects and to mimic human diseases. Similar DNA sequences between both species facilitate these types of experiments.
Carlos A. Garcia-Prieto +6 more
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Infant leukaemias,Congenital leukaemias,Neonatal leukaemias [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2020 Review on congenital/neonatal and infant leukemias, with data on clinics, pathology, and involved genes.
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HemaSphere, 2022 Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic disorders characterized by dysplasia, ineffective hematopoiesis, and predisposition to secondary acute myeloid leukemias (sAML).
Marguerite-Marie Le Pannérer +9 more
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A Trib2-p38 axis controls myeloid leukaemia cell cycle and stress response signalling [PDF]
, 2018 Trib2 pseudokinase is involved in the etiology of a number of cancers including leukaemia, melanoma, ovarian, lung and liver cancer. Both high and low Trib2 expression levels correlate with different types of cancer.
Carmody, Ruaidhri J. +6 more
core +2 more sources