Results 11 to 20 of about 184,092 (245)

The Use of Aerial Radiometrics for Epidemiological Studies of Leukaemia: a Preliminary Investigation in SW England [PDF]

, 1993
The report presents the results and conclusions of a pilot study designed to evaluate the potential use of aerial gamma ray measurements in epidemiological investigations of leukaemia.
Scott, E.M., Baxter, M.S., Martin, E., Sanderson, D.C.W., Ni Riain, S., University of Glasgow: Scottish Universities Research and Reactor Centre   +5 more
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The role of homeobox gene in leukaemia [PDF]

, 2013
This thesis was submitted for the degree of Master of Philosophy and was awarded by Brunel UniversityHomeobox genes are known to be active during development and they are turned off after the early stages of developmental life.
Alshehri, Areej
core   +7 more sources

The detection and classification of blast cell in Leukaemia Acute Promyelocytic Leukaemia (AML M3) blood using simulated annealing and neural networks [PDF]

, 2011
This paper was delivered at AIME 2011: 13th Conference on Artifical Intelligence in Medicine.This paper presents a method for the detection and classification of blast cells in M3 with others sub-types using simulated annealing and neural networks.
Ismail, W, Swift, S, Hassan, R, Payne, A
core   +6 more sources

Childhood leukaemia: long-term excess mortality and the proportion 'cured'. [PDF]

, 2008
Survival from childhood leukaemia has increased, but the proportion of children cured is unknown. The proportion 'cured' is defined as the proportion of survivors for whom, as a group, there is no longer excess mortality compared to the general ...
Shah, A., Vincent, T., Eden, TOB, Coleman, M. P., Stiller, C. A., Eden, T. O. B., T Vincent, T O B Eden, A Shah, M G Kenward, Kenward, M. G., Stiller, CA, Coleman, MP, Shah, A, Kenward, MG, Vincent, T, C A Stiller, M P Coleman, Eden, Tim O B, Coleman, M P, Stiller, C A, Kenward, M G   +21 more
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Inhibition of CBP synergizes with the RNA-dependent mechanisms of Azacitidine by limiting protein synthesis

Nature Communications, 2021
Azacitidine (AZA) treatment is used for patients with myelodysplasias that cannot undergo bone marrow transplantation; however, AZA treatment is only partially effective.
Jeannine Diesch, Marguerite-Marie Le Pannérer, René Winkler, Raquel Casquero, Matthias Muhar, Mark van der Garde, Michael Maher, Carolina Martínez Herráez, Joan J. Bech-Serra, Michaela Fellner, Philipp Rathert, Nigel Brooks, Lurdes Zamora, Antonio Gentilella, Carolina de la Torre, Johannes Zuber, Katharina S. Götze, Marcus Buschbeck   +17 more
doaj   +1 more source

Metabolic profile of leukemia cells influences treatment efficacy of L-asparaginase

BMC Cancer, 2020
Background Effectiveness of L-asparaginase administration in acute lymphoblastic leukemia treatment is mirrored in the overall outcome of patients.
Katerina Hlozkova, Alena Pecinova, Natividad Alquezar-Artieda, David Pajuelo-Reguera, Marketa Simcikova, Lenka Hovorkova, Katerina Rejlova, Marketa Zaliova, Tomas Mracek, Alexandra Kolenova, Jan Stary, Jan Trka, Julia Starkova   +12 more
doaj   +1 more source

The application of BH3 mimetics in myeloid leukemias

Cell Death and Disease, 2021
Execution of the intrinsic apoptotic pathway is controlled by the BCL-2 proteins at the level of the mitochondrial outer membrane (MOM). This family of proteins consists of prosurvival (e.g., BCL-2, MCL-1) and proapoptotic (e.g., BIM, BAD, HRK) members ...
Narissa Parry, Helen Wheadon, Mhairi Copland   +2 more
doaj   +1 more source

Low HOX gene expression in PML-RARα-positive leukemia results from suppressed histone demethylation

Epigenetics, 2018
Homeobox (HOX) genes are frequently dysregulated in leukemia. Previous studies have shown that aberrant HOX gene expression accompanies leukemogenesis and affects disease progression and leukemia patient survival.
Katerina Rejlova, Alena Musilova, Karolina Skvarova Kramarzova, Marketa Zaliova, Karel Fiser, Meritxell Alberich-Jorda, Jan Trka, Julia Starkova   +7 more
doaj   +1 more source

FT-infrared spectroscopic studies of lymphoma, lymphoid and myeloid leukaemia cell lines [PDF]

, 2007
This paper presents a novel method to characterise spectral differences that distinguish leukaemia and lymphoma cell lines. This is based on objective spectral measurements of major cellular biochemical constituents and multivariate spectral ...
Babrah, Jaspreet, McCarthy, Keith P., Lush, Richard, Bessant, Conrad M., Rye, Adam D., Stone, Nicholas, Jaspreet Babrah, Adam D. Rye, Nicholas Stone, Keith P. McCarthy, Richard Lush, Conrad Bessant   +11 more
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Dasatinib inhibits CXCR4 signaling in chronic lymphocytic leukaemia cells and impairs migration towards CXCL12 [PDF]

, 2012
Chemokines and their ligands play a critical role in enabling chronic lymphocytic leukaemia (CLL) cells access to protective microenvironmental niches within tissues, ultimately resulting in chemoresistance and relapse: disruption of these signaling ...
McCaig, Alison M., Alison M McCaig, Alison M. Mccaig, Cosimo Emilio, Alison M. Michie, Leach Michael T., Alison M Michie, Emilio Cosimo, Michael T. Leach, McCaig Alison M., Michael T Leach, Michie, Alison M., Michie Alison M., Cosimo, Emilio, Leach, Michael T.   +14 more
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