Results 151 to 160 of about 420,896 (315)

Peripheral Leukocyte Kinetic Studies of Acute Leukemia in Relapse and Remission and Chronic Myelocytic Leukemia in Blastic Crisis [PDF]

, 1968
Herman A. Godwin, T S Zimmerman, Seymour Perry   +2 more
openalex   +1 more source

CXCR1 Depletion in Ly6C+ cDC2 Alleviates Acute Lung Injury via Modulation of Th17/Treg Balance

Advanced Science, EarlyView.
Pro‐inflammatory Ly6C⁺ cDC2s are identified as key effector cells mediating Cxcr1 signaling, driving the progression of ALI. Ly6C⁺ cDC2s release high levels of Il‐6 and Il‐1β, inducing Th17 differentiation. Cxcr1 deficiency reduces Il‐6 and Il‐1β production from Ly6C⁺ cDC2s through suppressing MEK1/ERK /NF‐κB signaling, thereby shifts naïve T cells ...
Shenghui Li, Wei Zhuang, Yang Wang, Hao Qin, Xichun Qin, Xianliang Yan, Xuefei Hu, Xiucheng Liu, Chang Chen   +8 more
wiley   +1 more source

Marrow transplantation for patients with acute lymphoblastic leukemia in remission [PDF]

, 1979
Thomas Ed, JE Sanders, Nancy Flournoy, F L Johnson, CD Buckner, Clift Ra, A Fefer, BW Goodell, R Storb, PL Weiden   +9 more
openalex   +3 more sources

Rare germline ETV6 variant associated with thrombocytopenia and acute leukemia. [PDF]

Ann Hematol
Rajendra Kurup A, Malcolmson J, Villani A, Kim RH, Yee KW.   +4 more
europepmc   +1 more source

Gigaxonin Potentiates Antiviral Innate Immune Responses by Targeting cGAS and TREX1

Advanced Science, EarlyView.
TREX1 antagonizes DNA sensor cGAS by degrading cytosolic DNA. This work identifies gigaxonin as a molecular switch that coordinates DNA sensing and clearance pathways to amplify antiviral responses. Under the steady state, gigaxonin maintains cellular homeostasis by mediating TREX1 ubiquitination and proteasomal degradation. During DNA virus infection,
Ben‐Zhe Ji, Jie Wang, Yi Tu, Shan Zhang, Yong‐Sheng Wei, Yan He, Bin Zhang, Qing‐Qing Zhao, Hao‐Min Hu, Yu Liu   +9 more
wiley   +1 more source

Second allogeneic transplantation in relapsed acute leukemia - a risk worth taking? [PDF]

Ann Hematol
Zielińska P, Gruenpeter K, Wieczorkiewicz-Kabut A, Białas K, Koclęga A, Noster I, Szewczyk I, Boral K, Wiśniewska-Piąty K, Butrym A, Czyż J, Lutwin E, Helbig G.   +12 more
europepmc   +1 more source

Different Patterns of Remisson in Acute Myelocytic Leukemia [PDF]

, 1963
Robert H. Levin, Geoffrey M. Brittin, Emil J. Freireich   +2 more
openalex   +1 more source

Loss of Hepatic Angiotensinogen Attenuates Diastolic Dysfunction in Heart Failure with Preserved Ejection Fraction

Advanced Science, EarlyView.
Increased hepatic angiotensinogen (AGT) abundance leads to cardiac diastolic dysfunction via the AngII‐independent pathway. Liver‐derived AGT is internalized by LRP2 in cardiac endothelial cells, subsequently contributing to myocardial diastolic dysfunction by suppressing microvascular angiogenesis via inhibiting the GATA2/Pim3 pathway.
Zetao Heng, Min Hong, Zhaocai Zhang, Ximing Ye, Jianan Zhou, Wentao Wu, Jiabing Rong, Yinchuan Xu   +7 more
wiley   +1 more source

Analyses of transplantation outcomes for adult patients with mixed-phenotype acute leukemia. [PDF]

Blood Neoplasia
Jo T, Kondo T, Mizuno S, Kako S, Doki N, Uchida N, Tanaka M, Nishida T, Fukuda T, Sawa M, Kanda Y, Takada S, Hasegawa Y, Katayama Y, Yoshihara S, Kawamura K, Ohbiki M, Atsuta Y, Yanada M, Arai Y.   +19 more
europepmc   +1 more source

CDH1 Orchestrates Anabolic Events to Promote Cell Cycle Initiation

Advanced Science, EarlyView.
Cell proliferation requires the integration of cell cycle and anabolic signals. G1‐phase regulator CDH1 coordinates anabolism through the CDH1‐VHL‐AARS2/HIF1α axis, while CDH1‐accumulated R5P is sensed by TKTL1 to facilitate CDH1 degradation and cell cycle initiation, constituting a CDH1‐centered regulatory circuit.
Yun‐Zi Mao, Jiao‐Jiao Zhang, Meng‐Qi You, Han Wang, Yan Lin, Yuan Fang, Hui‐Lu Zhang, Yuan‐Yuan Qu, Qian Zhou, Meng Wang, Gang Li, Zi‐Fan Guo, Meng Xu, Jie Liu, Peng‐Cheng Lin, Yi‐Yuan Yuan, Yu Kang, Shi‐Min Zhao, Wei Xu   +18 more
wiley   +1 more source