Results 221 to 230 of about 313,407 (265)
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Annals of Internal Medicine, 1968
Excerpt I would rather learn from one bird how to sing than teach ten thousand stars how not to dance. e. e.
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Excerpt I would rather learn from one bird how to sing than teach ten thousand stars how not to dance. e. e.
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Current Problems in Cancer, 1997
Untreated acute leukemia is a uniformly fatal disease with a median survival time shorter than 3 months. Current treatment strategies provide a significant increase in survival time for most patients, some of whom may be cured. The majority of patients with acute leukemia, however, ultimately die of the disease or complications of treatment.
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Untreated acute leukemia is a uniformly fatal disease with a median survival time shorter than 3 months. Current treatment strategies provide a significant increase in survival time for most patients, some of whom may be cured. The majority of patients with acute leukemia, however, ultimately die of the disease or complications of treatment.
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Human Genetics, 1979
The karyotype of leukemic cells of 78 acute leukemia patients (37 ANLL, 34ALL, and 7 of unknown type) was studied by means of G-banding. Chromosomal abnormalities were found in 50 patients (72%). Chromosomes 8,21,5,7,11, and 19 were preferentially involved in the abnormalities, both in ANLL and in ALL.
E L, Prigogina +8 more
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The karyotype of leukemic cells of 78 acute leukemia patients (37 ANLL, 34ALL, and 7 of unknown type) was studied by means of G-banding. Chromosomal abnormalities were found in 50 patients (72%). Chromosomes 8,21,5,7,11, and 19 were preferentially involved in the abnormalities, both in ANLL and in ALL.
E L, Prigogina +8 more
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Pediatric Annals, 1983
During the past decade progress in the treatment of childhood acute lymphoblastic leukemia has slowed. A 50% to 60% cure barrier has frustrated a multitudinous array of therapeutic attempts to overcome this obstacle. With few exceptions, intensifications of induction, consolidation, or maintenance therapies have not overcome this obstacle.
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During the past decade progress in the treatment of childhood acute lymphoblastic leukemia has slowed. A 50% to 60% cure barrier has frustrated a multitudinous array of therapeutic attempts to overcome this obstacle. With few exceptions, intensifications of induction, consolidation, or maintenance therapies have not overcome this obstacle.
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Blood, 2013
Abstract There is growing research interest in the mammalian Tribbles (Trib) family of serine/threonine pseudokinases and their oncogenic association with acute leukemias. This review is to understand the role of Trib genes in hematopoietic malignancies and their potential as targets for novel therapeutic strategies in acute myeloid ...
Kai Ling, Liang +2 more
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Abstract There is growing research interest in the mammalian Tribbles (Trib) family of serine/threonine pseudokinases and their oncogenic association with acute leukemias. This review is to understand the role of Trib genes in hematopoietic malignancies and their potential as targets for novel therapeutic strategies in acute myeloid ...
Kai Ling, Liang +2 more
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Leukocytoreduction for Acute Leukemia
Therapeutic Apheresis, 2002Abstract: Both in children and adults, acute leukemia may present with extremely high blast counts; a phenomenon known as hyperleukocytosis. Respiratory failure, intracranial bleeding, and severe metabolic abnormalities frequently occur in acute hyperleukocytic leukemias (AHLs) and are the primary determinants of the high early mortality (20% to 40 ...
Pierluigi, Porcu +5 more
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Acute progranulocytic leukemia
Current Opinion in Oncology, 2001Acute progranulocytic leukemia (APL) is characterized by unique biologic and clinical features. Understanding of these unique features has resulted in dramatic improvements in therapy for patients with APL. Current therapy with all-trans-retinoic acid (ATRA) plus an anthracycline with or without cytosine-arabinoside has yielded complete response rates ...
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Classification of Acute Leukemia
Annals of Internal Medicine, 1977The classification of acute leukemia has almost invariably been based on the morphologic diagnosis into two broad categories: acute lymphocytic and acute myeloid leukemia. Despite the wide range of morphologic variation in both groups, strict criteria to define the subgroups have only recently been proposed.
HARVEY R. GRALNICK +4 more
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Annals of Internal Medicine, 1972
Excerpt The conventional classification of leukemias is based on the morphological cell lines (myelocytic, lymphocytic, monocytic) and the clinical course of the disease (acute or chronic).
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Excerpt The conventional classification of leukemias is based on the morphological cell lines (myelocytic, lymphocytic, monocytic) and the clinical course of the disease (acute or chronic).
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Clinics in Laboratory Medicine, 1999
This article reviews the laboratory methodologies used to evaluate acute lymphoblastic leukemia (ALL) in children and their role in establishing a diagnosis and prognosis of this disease. These methodologies are: morphology, flow cytometry, cytogenetics, and molecular diagnostics.
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This article reviews the laboratory methodologies used to evaluate acute lymphoblastic leukemia (ALL) in children and their role in establishing a diagnosis and prognosis of this disease. These methodologies are: morphology, flow cytometry, cytogenetics, and molecular diagnostics.
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