Results 61 to 70 of about 1,006,426 (373)
Hepatosplenic sarcoidosis complicated by liver cirrhosis [PDF]
, 2015 Sarcoidosis is a multisystemic disease usually affecting the lungs and mediastinal lymph nodes. Other organs, such as the liver and the spleen, are less commonly involved. Patients usually present with mild nonspecific symptoms.
Bernard, Philippe +4 more
core +3 more sources
Frontiers in Physiology, 2015 Massive hepatic necrosis is a key event underlying acute liver failure, a serious clinical syndrome with high mortality. Massive hepatic necrosis in acute liver failure has unique pathophysiological characteristics including extremely rapid parenchymal ...
Honglei eWeng +6 more
doaj +1 more source
Mechanism of glycyrrhizin on ferroptosis during acute liver failure by inhibiting oxidative stress
Molecular Medicine Reports, 2019 The present study aimed to investigate the anti-ferroptosis effects of the HMGB1 inhibitor glycyrrhizin (GLY). The present study used a cell and animal model of acute liver failure (ALF), induced using tumor necrosis factor-α, lipopolysaccharide and D ...
Yao Wang +4 more
semanticscholar +1 more source
Leukocytes, Systemic Inflammation and Immunopathology in Acute-on-Chronic Liver Failure
Cells, 2020 Acute-on-chronic liver failure (ACLF) is a complex syndrome that develops in patients with cirrhosis and is characterized by acute decompensation, organ failure(s) and high short-term mortality.
M. Casulleras +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Biallelic mutations in NBAS cause recurrent acute liver failure with onset in infancy [PDF]
, 2015 Acute liver failure (ALF) in infancy and childhood is a life-threatening emergency. Few conditions are known to cause recurrent acute liver failure (RALF), and in about 50% of cases, the underlying molecular cause remains unresolved.
Bader, Daniel M. +31 more
core +1 more source
Acute liver failure in adults [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2019 This article summarizes data on etiology, epidemiology and clinical presentation of acute liver failure. The review provides statistics on the incidence rates of acute liver failure in patients with different underlying diseases, describes the most ...
Lukashik S.P., Karpov I.A.
doaj +1 more source
Prognostic Markers in Pediatric Acute Liver Failure
GE: Portuguese Journal of Gastroenterology, 2023 Introduction: Acute liver failure (ALF), although rare in children, is a complex progressive pathology, with multisystem involvement and high mortality.
Andreia Filipa Nogueira +6 more
doaj +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Coexisting Sickle Cell Anemia and Sarcoidosis: A Management Conundrum! [PDF]
, 2017 Sickle cell disease and Sarcoidosis are conditions that are more common in the African American population. In this report we share an unfortunate patient who had hepatic sarcoidosis but could not receive steroids since that precipitated acute liver ...
Gollahalli, Nagesh S., Nutan, FNU
core +3 more sources