Results 161 to 170 of about 3,455,272 (209)

Mechanisms of Acute Lung Injury

Clinics in Laboratory Medicine, 1983
The role of the complement system in generating an acute inflammatory response in the lung, manifested particularly by the presence of neutrophils, and the role of these neutrophils in altering lung microvascular permeability are examined. Although it is not possible at this time to reconcile all the experimental data so as to provide a unifying ...
G S, Worthen, P M, Henson
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Managing Acute Lung Injury

Clinics in Chest Medicine, 2016
The foundation of mechanical ventilation for acute respiratory distress syndrome involves limiting lung overdistention by using small tidal volumes or transpulmonary pressures. Potential for additional lung recruitment with higher positive end-expiratory pressure (PEEP) should be assessed.
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Aspiration and acute lung injury

International Journal of Obstetric Anesthesia, 1993
Aspiration is a common clinical entity whose consequences range from the relatively benign to fulminant acute respiratory failure and death. Clinical situations in which airway protection is lost or compromised predispose patients to aspiration. Treatment of aspiration, while generally supportive, depends in part upon the material aspirated and the ...
M G, Lykens, D L, Bowton
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Biomarkers in acute lung injury

Respiratory Physiology & Neurobiology, 2015
Acute respiratory distress syndrome (ARDS) and its milder form acute lung injury (ALI) may result from various diseases and situations including sepsis, pneumonia, trauma, acute pancreatitis, aspiration of gastric contents, near-drowning etc. ALI/ARDS is characterized by diffuse alveolar injury, lung edema formation, neutrophil-derived inflammation ...
Daniela, Mokra, Petra, Kosutova
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Acute lung injury in the child

Paediatric Respiratory Reviews, 2010
Acute lung injury(ALI) is an important condition in critically ill children, contributing to overall mortality and morbidity. ALI represents the severe spectrum of lower airways disease in children. It is the pathological culmination of diseases such as pneumonia and sepsis.
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Pharmacology of Acute Lung Injury

Pulmonary Pharmacology & Therapeutics, 2002
The acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a clinical syndrome that affects both medical and surgical patients. To date, despite improved understanding of the pathogenesis of ALI/ARDS, pharmacological modalities have been unsuccessful in decreasing mortality.
Sadatomo, Tasaka, Naoki, Hasegawa, Akitoshi, Ishizaka   +2 more
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Pathophysiology of Acute Lung Injury

Seminars in Respiratory and Critical Care Medicine, 2001
The acute respiratory distress syndrome (ARDS) is a life-threatening syndrome that may occur in any patient without any predisposition and that is mostly triggered by underlying processes such as sepsis, pneumonia, trauma, multiple transfusions, and pancreatitis. ARDS is defined by (1) acute onset, (2) bilateral infiltrates in chest x-rays, (3) absence
A, Günther, D, Walmrath, F, Grimminger, W, Seeger   +3 more
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Neutrophils and acute lung injury

Critical Care Medicine, 2003
Neutrophils are an important component of the inflammatory response that characterizes acute lung injury (ALI). This discussion aims to review the contribution of neutrophils to the development and progression of ALI and to highlight the major intracellular signaling pathways that are involved in neutrophil activation in the setting of ALI.MEDLINE ...
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Sphingolipids in Acute Lung Injury

2013
Acute lung injury is a life-threatening disease that is characterized by pulmonary inflammation, loss of barrier functions, and hypoxemia. Sphingolipids are critically involved in the disease process that they can both expedite and extenuate: They expedite inflammation by promoting chemotaxis (neutral sphingomyelinase), increased endothelial ...
Stefan, Uhlig, Yang, Yang
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Pharmaconutrition in Acute Lung Injury

JAMA, 2011
DURING THE LAST DECADE, THERE HAS BEEN A MAJOR conceptual shift in thinking about artificial nutrition provided to critically ill patients. Because of its modulating effect on pathophysiology and emerging evidence about potential effects on clinical outcomes, nutrition is now considered “therapy” and not simply “supportive care.” For example, arginine ...
Deborah J, Cook, Daren K, Heyland
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