Results 221 to 230 of about 317,931 (266)

Sphingolipids in Acute Lung Injury

2013
Acute lung injury is a life-threatening disease that is characterized by pulmonary inflammation, loss of barrier functions, and hypoxemia. Sphingolipids are critically involved in the disease process that they can both expedite and extenuate: They expedite inflammation by promoting chemotaxis (neutral sphingomyelinase), increased endothelial ...
Stefan, Uhlig, Yang, Yang
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Pathophysiology of Acute Lung Injury

Seminars in Respiratory and Critical Care Medicine, 2001
The acute respiratory distress syndrome (ARDS) is a life-threatening syndrome that may occur in any patient without any predisposition and that is mostly triggered by underlying processes such as sepsis, pneumonia, trauma, multiple transfusions, and pancreatitis. ARDS is defined by (1) acute onset, (2) bilateral infiltrates in chest x-rays, (3) absence
A, Günther, D, Walmrath, F, Grimminger, W, Seeger   +3 more
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Aspiration and acute lung injury

International Journal of Obstetric Anesthesia, 1993
Aspiration is a common clinical entity whose consequences range from the relatively benign to fulminant acute respiratory failure and death. Clinical situations in which airway protection is lost or compromised predispose patients to aspiration. Treatment of aspiration, while generally supportive, depends in part upon the material aspirated and the ...
M G, Lykens, D L, Bowton
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Biomarkers in acute lung injury

Respiratory Physiology & Neurobiology, 2015
Acute respiratory distress syndrome (ARDS) and its milder form acute lung injury (ALI) may result from various diseases and situations including sepsis, pneumonia, trauma, acute pancreatitis, aspiration of gastric contents, near-drowning etc. ALI/ARDS is characterized by diffuse alveolar injury, lung edema formation, neutrophil-derived inflammation ...
Daniela, Mokra, Petra, Kosutova
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Mechanisms of acute lung injury

Current Opinion in Critical Care, 1997
Acute lung injury is the end result of common pathways initiated by a variety of local or systemic insults leading to diffuse damage to the pulmonary parenchyma. Despite the accumulation of abundant information regarding the physiological and cellular basis of lung injury and increasingly sophisticated intensive care, an improvement in prognosis has ...
G P, Downey, J T, Granton
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Neutrophils and acute lung injury

Critical Care Medicine, 2003
Neutrophils are an important component of the inflammatory response that characterizes acute lung injury (ALI). This discussion aims to review the contribution of neutrophils to the development and progression of ALI and to highlight the major intracellular signaling pathways that are involved in neutrophil activation in the setting of ALI.MEDLINE ...
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Glucocorticoids and acute lung injury

Critical Care Medicine, 2003
To describe hypothalamic-pituitary-adrenal (HPA) activation and the role of glucocorticoids in immune modulation during critical illness, and to review clinical trials of pharmacologic and "replacement"' doses of glucocorticoids in early and late acute respiratory distress syndrome (ARDS) and sepsis.Selected review of published literature (1963 to ...
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Epidemiology of acute lung injury

Current Opinion in Critical Care, 2005
Acute lung injury and its extreme manifestation, acute respiratory distress syndrome, complicate a wide variety of serious medical and surgical conditions, only some of which affect the lung directly. Despite recent evidence-based advances in clinical management, acute lung injury and acute respiratory distress syndrome are associated with significant ...
Niall S, MacCallum, Timothy W, Evans
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Pharmaconutrition in Acute Lung Injury

JAMA, 2011
DURING THE LAST DECADE, THERE HAS BEEN A MAJOR conceptual shift in thinking about artificial nutrition provided to critically ill patients. Because of its modulating effect on pathophysiology and emerging evidence about potential effects on clinical outcomes, nutrition is now considered “therapy” and not simply “supportive care.” For example, arginine ...
Deborah J, Cook, Daren K, Heyland
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Autophagy in Acute Lung Injury

Cell Biochemistry and Biophysics
Acute lung injury (ALI) is a critical condition marked by rapid-onset respiratory failure due to extensive inflammation and increased pulmonary vascular permeability, often progressing to acute respiratory distress syndrome (ARDS) with high mortality.
Danjuan, Liu, Shuoyun, Weng, Chunjin, Fu, Rongjie, Guo, Min, Chen, Bingbing, Shi, Junting, Weng   +6 more
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