Results 241 to 250 of about 318,103 (313)

Imaging‐Guided Live Single‐Cell Lipid Profiling of Leader and Follower Cellsduring Collective Migration of Triple‐Negative Breast Cancer Cells

Advanced Science, EarlyView.
Integrated single‐cell mass spectrometry reveals distinct lipidomic signatures that differentiate leader and follower phenotypes in migratory breast cancer cells. Phenotype‐specific alterations across various lipid classes, including fatty acids and phosphatidylcholines, underpin functional heterogeneity.
Xiaoyue Huang, Judit González Riera, Mai Nguyen, Jeremy Broekhuis, Sylvia E. Le Dévédec, Ahmed Ali, Thomas Hankemeier   +6 more
wiley   +1 more source

Circular RNAs in sepsis-induced acute lung injury: emerging mechanisms and therapeutic potential. [PDF]

Front Immunol
Liu Q, Wang Y, Liao H, Ren D, Guo W, Xu J, Duan C, Luo Z, Jiang W.   +8 more
europepmc   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Extracellular vesicles as emerging platforms for modulating innate immune responses in sepsis-associated acute lung injury. [PDF]

Front Immunol
Yan H, Zhang L, Lv X, Guo T, Wang Q, Zhang J.   +5 more
europepmc   +1 more source

An Edible Biohybrid Platform Accomplishes In Situ Fenton‐Mediated Enteral Nanoplastics Aging and Excretion

Advanced Science, EarlyView.
An edible biohybrid platform triggers nanoplastics (NPs) aging and agglomeration by in situ generating hydroxyl radicals within the intestine. The enlarged NPs are unable to penetrate the intestine and are subsequently excreted. Simultaneously, probiotic biofilms reinforce the intestinal barrier.
Su Zhou, Anran Yan, Haowei Guo, Ping Chen, Qiang Chu   +4 more
wiley   +1 more source

Engineering Resatorvid-Loaded Sub-Microgels of Epigallocatechin-3-gallate/Hyaluronic Acid to Treat Acute Lung Injury. [PDF]

Adv Healthc Mater
Liu B, Alimi OA, Stearnes B, Romanova S, Sillman BJ, Krishnan MA, Bailey K, Edagwa BJ, Chen HJ, Wang HJ, Duan B.   +10 more
europepmc   +1 more source

Toward Nano‐Nutritional Medicine: A Remotely Activated Trans‐Vaccenic Acid‐Based Lipid Nanoparticles for Enhancing Immune Checkpoint Blockade Therapy

Advanced Science, EarlyView.
Eutectic mixtures from trans‐vaccenic acid (TVA) and stearic acid, which served as phase‐change material to encapsulate IR780, forming NIR‐responsive nanoparticles. IR780@TVA LNPs induce photothermal therapy and initiate adaptive anti‐tumor immunity.
Kang Liu, Yunlong Li, Hanmeng Liu, Peng Zhang, Mingjing Wang, Quanwei Sun, Wenshuo Yang, Zhengwei Song, Song Tan, Ye Yang, Peng She, Dengke Yin, Wei Shen   +12 more
wiley   +1 more source

Postoperative transfusion-related acute lung injury in a young woman with corpus luteum cyst rupture: Case report and literature review. [PDF]

J Int Med Res
Wang J, Yang S, Cao H, Khaoula B, Liu R.
europepmc   +1 more source

NLRX1 alleviates sepsis-induced acute lung injury by activating mitophagy and suppressing NLRP3 inflammasome activation. [PDF]

Front Pharmacol
Hu Z, Ding J, Huo M, Lu Y, Wang R, Zhang L, Li D.   +6 more
europepmc   +1 more source

Acute lung injury: pathogenesis and treatment. [PDF]

J Transl Med
Liu H, Dong J, Xu C, Ni Y, Ye Z, Sun Z, Fan H, Chen Y.   +7 more
europepmc   +1 more source