Results 121 to 130 of about 223,598 (343)

RanBALL: An Ensemble Machine Learning Framework for Accurate Subtype Identification of Pediatric B‐Cell Acute Lymphoblastic Leukemia

Advanced Intelligent Systems, EarlyView.
Here, we present RanBALL, an ensemble random projection‐based model for accurate and cost‐effective identification of B‐cell acute lymphoblastic leukemia subtypes is presented. By preserving patient‐to‐patient distance after dimension reduction by random projection and ensemble learning, RanBALL can facilitate the discovery of B‐ALL subtype‐specific ...
Lusheng Li, Hanyu Xiao, Xinchao Wu, Zhenya Tang, Joseph D. Khoury, Jieqiong Wang, Shibiao Wan   +6 more
wiley   +1 more source

A Population‐Based Assessment of Cancer Risk in Children With VACTERL

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cancer risk in children with VACTERL, a nonrandom co‐occurrence of ≥ 3 defects (vertebral, anal, cardiac, tracheoesophogeal fistula, renal, and limb), remains unclear. We evaluated this association in a population‐based study. We analyzed data from the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Study, a US registry linkage ...
Ji Yun Tark, Alexander Renwick, Giorgio Tettamanti, Rachel D. Harris, Tania A. Desrosiers, Andrew F. Olshan, Amanda E. Janitz, Michael E. Scheurer, Charles J. Shumate, Angela E. Scheuerle, Sharon E. Plon, Chad D. Huff, Ann Nordgren, Barbara Luke, Philip J. Lupo, Jeremy M. Schraw   +15 more
wiley   +1 more source

Variations in non-pharmacological anti-infective measures in childhood leukemia – results of an international survey

Haematologica, 2012
Background Standardization in clinical practice may lead to improved outcomes. Unfortunately, little is known about the variability of non-pharmacological anti-infective measures in children with cancer.Design and Methods A web-based survey assessed ...
Thomas Lehrnbecher, Richard Aplenc, Fernanda Rivas Pereira, Alvaro Lassaletta, Désirée Caselli, Jerzy Kowalczyk, Julia Chisholm, Lillian Sung   +7 more
doaj   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Predictors of etiology and drug resistance in children with new‐onset focal seizures

Epilepsia Open, EarlyView.
Abstract Objective To examine the clinical features of new‐onset focal seizures in children and investigate clinical associations and predictors of underlying etiology and drug resistance. Methods Data were gathered from The Children's Hospital at Westmead admissions for patients aged 1 month to 18 years who presented with new‐onset focal seizures ...
Byoung Chan Lee, Russell C. Dale, Elizabeth H. Barnes, Shekeeb S. Mohammad, Sachin Gupta, Chong Wong, Deepak Gill, Kavitha Kothur   +7 more
wiley   +1 more source

A comprehensive consolidation of data on the connection between CDKN2A polymorphisms and the susceptibility to childhood acute lymphoblastic leukemia

Hematology, Transfusion and Cell Therapy
Background: Acute lymphoblastic leukemia is the predominant neoplastic ailment in childhood. Prior research has already established noteworthy connections between CDKN2A polymorphisms and susceptibility to this childhood leukemia, however, substantial ...
Maryam Aghasipour, Fatemeh Asadian, Seyed Alireza Dastgheib, Abolhasan Alijanpour, Ali Masoudi, Maedeh Barahman, Mohammad Golshan-Tafti, Reza Bahrami, Amirmasoud Shiri, Hossein Aarafi, Kazem Aghili, Hossein Neamatzadeh   +11 more
doaj   +1 more source

IKZF1 genetic variants rs4132601 and rs11978267 and acute lymphoblastic leukemia risk in Tunisian children: a case-control study [PDF]

, 2019
Sana Mahjoub, Vera Chayeb, Hédia Zitouni, Rabeb M. Ghali, H. Regaïeg, Wassim Y. Almawi, Touhami Mahjoub   +6 more
openalex   +1 more source

Successful treatment of COVID‐associated fungal infection due to Scopulariopsis and Aspergillus in a girl with acute lymphoblastic leukemia [PDF]

, 2023
Shih‐Hsiang Chen, Tsung‐Yen Chang, Chen‐Yen Kuo, C. C. Chang, Tang‐Her Jaing, Chih‐Jung Chen, Yhu‐Chering Huang, Cheng‐Hsun Chiu   +7 more
openalex   +1 more source

Genetic alterations in myeloid sarcoma among acute myeloid leukemia patients: insights from 37 cohort studies and a meta-analysis

Frontiers in Oncology
IntroductionVariations in mutation rates among acute myeloid leukemia (AML) patients with myeloid sarcoma (MS) underscore the need for a thorough examination. This meta-analysis was conducted to fill the information gap concerning mutation frequencies in
Suvijak Untaaveesup, Sasinipa Trithiphen, Kamolchanok Kulchutisin, Tarinee Rungjirajittranon, Tarinee Rungjirajittranon, Nattawut Leelakanok, Sujitra Panyoy, Thanapon Kaokunakorn, Weerapat Owattanapanich, Weerapat Owattanapanich   +9 more
doaj   +1 more source

Peer Review of “Selection of the Optimal L-asparaginase II Against Acute Lymphoblastic Leukemia: An In Silico Approach“ [PDF]

, 2021
Navneetha Hardikar
openalex   +1 more source