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Pediatric Acute Lymphoblastic Leukemia
Hematology, 2003AbstractThe outcome for children with acute lymphoblastic leukemia (ALL) has improved dramatically with current therapy resulting in an event free survival exceeding 75% for most patients. However significant challenges remain including developing better methods to predict which patients can be cured with less toxic treatment and which ones will ...
William L, Carroll +8 more
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Pediatric Clinics of North America, 1980
The improved outlook in childhood leukemia can be attributed to more accurate diagnosis, better supportive care, the use of drug combinations to achieve and maintain remission, and prophylactic therapy to prevent central nervous system leukemia. With the best treatment available today, 65 to 70 per cent of children are in complete continuous remission ...
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The improved outlook in childhood leukemia can be attributed to more accurate diagnosis, better supportive care, the use of drug combinations to achieve and maintain remission, and prophylactic therapy to prevent central nervous system leukemia. With the best treatment available today, 65 to 70 per cent of children are in complete continuous remission ...
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Acute non-lymphoblastic leukemia
European Journal of Cancer (1965), 1978THE MOST recent reports [1, 2] of two controlled clinical trials of chemoprophylaxis in early breast cancer have confirmed that adjuvant chemotherapy to radical mastectomy in primary breast carcinoma with positive axi]lary lymph nodes can improve the 3yr relapse rate.
G. Robustelli +4 more
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Hematology/Oncology Clinics of North America, 2009
Acute lymphoblastic leukemia and lymphoblastic lymphoma constitute a family of genetically heterogeneous lymphoid neoplasms derived from B- and T-lymphoid progenitors. Diagnosis is based on morphologic, immunophenotypic, and genetic features that allow differentiation from normal progenitors and other hematopoietic and nonhematopoietic neoplasms ...
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Acute lymphoblastic leukemia and lymphoblastic lymphoma constitute a family of genetically heterogeneous lymphoid neoplasms derived from B- and T-lymphoid progenitors. Diagnosis is based on morphologic, immunophenotypic, and genetic features that allow differentiation from normal progenitors and other hematopoietic and nonhematopoietic neoplasms ...
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Best Practice & Research Clinical Haematology, 2001
Precursor B-ALL (BCP-ALL) is associated with a good outcome in children. Cytogenetics is one of the gold standards for risk stratification for treatment that has contributed to improved survival. Although in T-ALL genetic analysis has not been used to guide therapy, it has contributed significantly to the understanding of the biology.
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Precursor B-ALL (BCP-ALL) is associated with a good outcome in children. Cytogenetics is one of the gold standards for risk stratification for treatment that has contributed to improved survival. Although in T-ALL genetic analysis has not been used to guide therapy, it has contributed significantly to the understanding of the biology.
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Leukemia cutis in acute lymphoblastic leukemia
Journal of the American Academy of Dermatology, 1994separating normal epidermis from a diffuse dermal infiltrate of lymphoid blast cells with round and regular nuclei, inconspicuous nucleoli, and scanty, moderately basophilic cytoplasm. Immunophenotype analysis revealed strong positivity for CD 10.The patient wastreated with methotrexate, teniposide, cytosine arabinoside, and local irradiation, and a ...
J F, de Lacerda +5 more
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Acute Lymphoblastic Leukemia: Background
2003Acute lymphoblastic leukemia is a fascinating disease for the cytogeneticist, as so many cases have a clone detectable by cytogenetics or FISH, and because identifying the abnormalities provides such useful information to the clinician. However, it is also a frustrating disease, as it has technical challenges such as a marked tendency for the sample to
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2007
Acute lymphoblastic leukemias (ALLs) are a group of hematological neoplasias defined by cytomorphology, cytochemistry, immunological markers, and more recently, molecular markers. The prognosis of ALL has much improved in the last 30 yr, especially in the age group between 2 and 10 yr, where most patients can be cured by chemotherapy.
Reinhold Munker, Vishwas Sakhalkar
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Acute lymphoblastic leukemias (ALLs) are a group of hematological neoplasias defined by cytomorphology, cytochemistry, immunological markers, and more recently, molecular markers. The prognosis of ALL has much improved in the last 30 yr, especially in the age group between 2 and 10 yr, where most patients can be cured by chemotherapy.
Reinhold Munker, Vishwas Sakhalkar
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Relapsed acute lymphoblastic leukemia
American Journal of Ophthalmology, 2021Judy L. Chen +2 more
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