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Acute lymphoblastic leukemia in the elderly
European Journal of Haematology, 1990We report our findings in 18 patients with acute lymphoblastic leukemia (ALL) aged 60 years or older. A preleukemic syndrome was observed in 2 patients. Compared to younger adults with ALL, L3 morphology was unexpectedly frequent (4/16) T‐ALL was not observed. Other criteria of poor prognosis (high white blood cell count, CNS involvement, organomegaly,
Delannoy, André +7 more
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Chemoimmunotherapy in acute lymphoblastic leukemia
Blood Reviews, 2012ALL blast cells express a variety of specific antigens e.g. CD19, CD20, CD22, CD33, and CD52, which serve as targets for Monoclonal Antibodies (MoAbs). So far, the most experience is available for anti-CD20 (rituximab), which has been combined with chemotherapy for treatment of mature B-ALL/Burkitt's lymphoma.
Dieter, Hoelzer, Nicola, Gökbuget
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Immunophenotyping of Acute Lymphoblastic Leukemia
2019Immunophenotyping by flow cytometry is an important component in the diagnostic evaluation of patients with acute lymphoblastic leukemia. This technique further permits the detection of minimal residual disease after therapy, a robust prognostic factor that may guide individualized treatment.
Joseph A, DiGiuseppe +1 more
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Acute Lymphoblastic Leukemia: Background
2003Acute lymphoblastic leukemia is a fascinating disease for the cytogeneticist, as so many cases have a clone detectable by cytogenetics or FISH, and because identifying the abnormalities provides such useful information to the clinician. However, it is also a frustrating disease, as it has technical challenges such as a marked tendency for the sample to
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Advances in the Diagnosis and Treatment of Pediatric Acute Lymphoblastic Leukemia
Journal of Clinical Medicine, 2021Ching-Hon Pui +2 more
exaly
Hypercalcemia in acute lymphoblastic leukemia
Leukemia Research, 1994J F, Seymour, H M, Kantarjian
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Minimal Residual Disease Detection in Acute Lymphoblastic Leukemia
International Journal of Molecular Sciences, 2020Yongsheng Ruan +2 more
exaly