Results 91 to 100 of about 47,614 (291)

Successful remission induction in children with acute lymphocytic leukemia at high risk for treatment failure [PDF]

, 1971
Rhomes J. A. Aur, Joseph V. Simone, Charles B. Pratt   +2 more
openalex   +1 more source

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

Diagnosis Challenges in Adult Leukemia: Insights From a Single-Center Retrospective Study in Qatar (2016-2021)

Cancer Control
Objectives While delays in leukemia detection remain an ongoing challenge in hematologic cancer care, little is known about the factors associated with these delays.
Hesham A. B. Aboelkhir, Yousra El Alaoui MSc, Regina Padmanabhan PhD, Majed Hadid PhD, Adel Elomri PhD, Tanvir Alam PhD, Mohamed Amine Rejeb MBBS, Halima EL Omri MD, Ruba Y. Taha MD, Hesham Elsabah MD, Abdelfatteh EL Omri PhD   +10 more
doaj   +1 more source

Studies of mixed lymphocyte reactions, surface B cell antigens, and intracytoplasmic immunoglobulins in “null cell” acute lymphocytic leukemia [PDF]

, 1979
Frederick R. Davey, Nancy L. Dock, Jeffrey A. Wolos, James A. Terzian, Arlan J. Gottlieb   +4 more
openalex   +1 more source

Cryo‐Inactivated Cancer Cells Derived Magnetic Micromotors for Tumor Immunotherapy

Advanced Science, EarlyView.
Cryo‐inactivated cancer cell‐based magnetic micromotors are developed for synergistic tumor immunotherapy via magnetic targeting. These micromotors can induce ferroptosis and immunogenic cell death, deliver tumor antigens, and activate the Mn2+‐dependent cGAS‐STING pathway. The system effectively suppresses tumor progression, recurrence, and metastasis,
Qingfei Zhang, Gaizhen Kuang, Wenzhao Li, Yuanjin Zhao   +3 more
wiley   +1 more source

The t(5;14) chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 gene to the immunoglobulin heavy chain gene [PDF]

, 1989
J. Christopher Grimaldi, TC Meeker
openalex   +2 more sources

“Total therapy” studies of acute lymphocytic leukemia in children. Current results and prospects for cure [PDF]

, 1972
Joseph V. Simone, Rhomes J. A. Aur, H. Omar Hustu, Donald Pinkel   +3 more
openalex   +1 more source

Nanomaterials Trigger Functional Anti‐Tumoral Responses in Primary Human Immune Cells

Advanced Science, EarlyView.
Nanoparticles are used to improve immunomodulatory therapies, but the impact of drug‐free nanomaterials on the immune system remains unknown. Screening common biomedical nanoparticles (NPs) reveals that PLGA NPs enhanced NK cell anti‐tumoral activity and transcriptional activation in human NK and pan T cells.
Vincent Mittelheisser, Olivier Lefebvre, Mainak Banerjee, Shayamita Ghosh, Amandine Dupas, Marie‐Charlotte Diringer, Juliette Blumberger, Louis Bochler, Sébastien Harlepp, Annabel Larnicol, Angélique Pichot, Tristan Stemmelen, Anne Molitor, Chloé Moritz, Christine Carapito, Raphaël Carapito, Loïc J. Charbonnière, François Lux, Olivier Tillement, Jacky G. Goetz, Alexandre Detappe   +20 more
wiley   +1 more source

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

Advanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei, Chi Wang, Xiangyan Chen, Yuanyuan Zhu, Mei Yang, Ningxi Li, Honglin Huang, Guangjian Zhang, Mingzhen Zhang, Yiyao Liu, Rui Gao   +10 more
wiley   +1 more source

Probable ponatinib-induced papilledema in a patient with acute lymphocytic leukemia. [PDF]

Am J Ophthalmol Case Rep, 2023
Moon JA, Bowden EC, Aung MH.
europepmc   +1 more source