Results 71 to 80 of about 2,092,286 (303)

Induction therapy for adults with acute lymphoblastic leukemia: results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993 [PDF]

, 2005
The international acute lymphoblastic leukemia (ALL) study was designed to prospectively define the optimal therapy for adults 60 years of age or younger with newly diagnosed ALL.
Burnett, Alan Kenneth, Franklin, IM, Rowe, Jacob M., Richards, SM, Litzow, Mark R., Wiernik, P.H., Tallman, Martin S., Rowe, JM, Prentice, H. Grant, Goldstone, Anthony H., Wiernik, PH, Litzow, M.R., Litzow, MR, Ciobanu, N, Ciobanu, N., Prentice, HG, Durrant, J., Richards, Susan M., Durrant, J, Lazarus, H.M., Goldstone, A.H., Chopra, R, Lazarus, Hillard M., Wiernik, Peter H., Ciobanu, Niculae, Rowe, J.M., Tallman, MS, Durrant, Jill, Chopra, R., Lazarus, HM, Burnett, AK, Burnett, A.K., Buck, Georgina, Buck, G., Franklin, Ian M., Chopra, Raj, Goldstone, AH, Prentice, H.G., Richards, S.M., Tallman, M.S., Buck, G, Franklin, I.M., Chopra, Rajesh, Burnett, Alan K, Lazarus, Hillard M, Richards, Susan M, Wiernik, Peter H, Goldstone, Anthony H, Franklin, Ian M, Rowe, Jacob M, Durrant, I Jill, Tallman, Martin S, Litzow, Mark R, Prentice, H Grant   +53 more
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PDHA1 Hyperactivation‐Mediated Glucose Metabolism Reprogramming Fuels Neutrophil NETosis and Promotes Acute Lung Injury

Advanced Science, EarlyView.
During NETosis, neutrophils shift metabolically toward enhanced OXPHOS and partially reduced glycolysis. This shift is driven by PDHA1 hyperactivity‐dependent selective metabolic reprogramming. The neutrophil‐targeted nanoparticle 3‑FP‑BSA NPs effectively inhibit NETosis and attenuate ALI.
Yu‐Biao Liu, Wen‐Jing Zhong, Chen‐Yu Zhang, Meng‐Rui Chen, Nan‐Shi‐Yu Yang, Han‐Xi Sha, Yan‐Ling Qiu, Hui Chen, Jin‐Tong Yang, Li‐Ying Liang, Jian‐Bing Xiong, Shao‐Kun Liu, Cha‐Xiang Guan, Jia‐Xi Duan, Yong Zhou   +14 more
wiley   +1 more source

Linear programming based computational technique for leukemia classification using gene expression profile.

PLoS ONE, 2023
Cancer is a serious public health concern worldwide and is the leading cause of death. Blood cancer is one of the most dangerous types of cancer. Leukemia is a type of cancer that affects the blood cell and bone marrow.
Mahwish Ilyas, Khalid Mahmood Aamir, Sana Manzoor, Mohamed Deriche   +3 more
doaj   +1 more source

A systematic review of economic evaluations for the pharmaceutical treatment of chronic lymphocytic leukemia and acute myeloid leukemia

, 2022
A systematic review of economic evaluations for the pharmaceutical treatment of chronic lymphocytic leukemia and acute myeloid ...
Dieu Nguyen (13067025), Peter Lee (13080795), Lan Gao (13070538)   +2 more
core  

Plasma Membrane Lipid Asymmetry Dynamically Regulates Passive Diffusion

Advanced Science, EarlyView.
Passive diffusion enables hydrophobic molecules to cross the plasma membrane and exert their biological functions. This study demonstrates that plasma membrane lipid asymmetry, dynamically regulated by lipid scrambling, determines membrane permeability to lipophilic molecules and thereby modulates their cellular activities.
Jieming Ping, Wenliang Wang, Jinnuo Xu, Mengyun Yang, Ning Wu   +4 more
wiley   +1 more source

Rare Coexistence of Atypical Chronic Lymphocytic Leukemia and B-Acute Lymphoblastic Leukemia in a Patient Followed Up for Monoclonal B-Cell Lymphocytosis

Hemato
Monoclonal B Lymphocytosis (MBL) is considered the pre-malignant state of chronic lymphocytic leukemia (CLL) and atypical chronic lymphocytic leukemia (aCLL).
Fabio Bertani, Francesco Faiella, Claudia Di Franco, Raffaella Milani, Antonella Gualdoni, Cinzia Fulceri, Elena Costa   +6 more
doaj   +1 more source

Characteristics of Acute Non-Lymphocytic Leukemia Cases and Controls in the SETIL Case-Control Study, Italy, 1998-2003.

, 2014
Abbreviations: AnLL, acute non-lymphocytic leukemia; NA, not appropriate.aComparison between cases and all controls sampled in the SETIL study (AnLL controls + ALL controls).bP values from χ2 test.cP values from Fisher exact test.dMatching variables ...
Andrea Farioli (519624), Lucia Miligi (662519), Roberto Rondelli (662523), Corrado Magnani (136968), Stefano Mattioli (24599), Alessandra Ranucci (662521), Alberto Salvan (662522), Alessandra Benvenuti (662520), Patrizia Legittimo (662518)   +8 more
core   +1 more source

Integrated Multiomic Analysis Reveals an EBV‐Associated MIF–SPP1+ Macrophage Axis Linking Tumor Stemness and Immune Dysfunction in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study maps how Epstein–Barr virus reshapes the cellular ecosystem of nasopharyngeal carcinoma. It identifies SPP1+ macrophages as partners of stemness‐associated tumor cells and dysfunctional T cells, links tumor‐derived MIF to macrophage recruitment and programming, and shows that macrophage‐derived SPP1 promotes tumorsphere formation and impairs
Guo‐Ying Liu, Shu‐Hui Lv, Shui‐Qing He, Yao‐Fei Jiang, Xing‐Si Peng, Jian‐Cong Sun, Fen He, Hai‐Yan Qin, Nian Lu, Wei‐Xin Bei, Lin‐Yu Zhao, Wan‐Qin Shen, Ze‐Yu Zhao, Lin Wang, Yan‐Qun Xiang, Wang‐Zhong Li   +15 more
wiley   +1 more source

Appearances can be deceptive: acute myeloid leukaemia simulating chronic lymphocytic leukaemia

Advances in Laboratory Medicine
To report a rare case of acute myeloid leukemia (AML) with abnormal chromatin clumping (ACC) in myeloblasts mimicking chronic lymphocytic leukemia (CLL), highlighting the associated diagnostic challenges.
Horsefield Beatriz Gómez, García David Cruz, Garzó Moreno Ana, Tuset Andujar Esperanza, Sierra Leire Saiz, Querol Maite Serrando   +5 more
doaj   +1 more source

Questions and answers about leukemia [PDF]

Leukemia is cancer of the white blood cells. It develops in the bone marrow and spreads into the blood and to other organs. There are several types of leukemia. They are grouped in two ways: by how rapidly the disease develops (acute vs. chronic leukemia)

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