Results 91 to 100 of about 2,092,286 (303)
The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
Animal Research and One Health, EarlyView.A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
Deconstructing Pediatric Acute Lymphocytic Leukemia
MedEdPORTAL, 2012 This is an online module which is aimed at teaching medical students key concepts about Pediatric Acute Lymphocytic Leukemia. At the end of this module, the learner will be able to: (1) Recognize different presenting symptoms of leukemia in pediatric ...
David Gass +4 more
doaj +1 more source
Ofatumumab – a valid treatment option for chronic lymphocytic leukemia patients [PDF]
, 2017 Salma M AlDallal Haematology Laboratory, Amiri Hospital, Kuwait City, Kuwait Abstract: Ofatumumab Arzerra® is a human monoclonal antibody, which induces killing of a panel of tumor B-cell lines and primary tumor cells by the activation of in vitro ...
AlDallal SM, Salma Al Dallal
core +1 more source
Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis
Arthritis &Rheumatology, EarlyView.Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm +2 more
wiley +1 more source
Turkish Journal of Hematology, 2013 Sweet syndrome, also referred to as acute febrile neutrophilic dermatosis, is characterized by tender, red inflammatory nodules or papules that occur in association with infection, malignancy, connective tissue disease, or following exposure to certain ...
Çiğdem Usul Afşar +6 more
doaj +1 more source
Role of ofatumumab in treatment of chronic lymphocytic leukemia [PDF]
, 2011 Marays Veliz, Javier Pinilla-IbarzH Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USAAbstract: The management of chronic lymphocytic leukemia (CLL) has dramatically improved in the past decade with the addition of anti-CD20 monoclonal ...
Pinilla-Ibarz J +3 more
core +1 more source
Arthritis &Rheumatology, Accepted Article.Objective Systemic sclerosis (SSc) is a chronic autoimmune disorder characterized by immune dysregulation and fibrosis, with myeloid‐derived suppressor cells (MDSCs) emerging as important regulators of immune responses. However, the role of MDSCs in SSc‐associated fibrosis and their interactions with other immune cell populations remain poorly ...
Stefanie Weber +15 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis +5 more
wiley +1 more source
Gomal Journal of Medical Sciences, 2018 Background: Bone marrow aspiration is a diagnostic test for various hematological malignancies. Present study was designed to determine the frequency of malignant Hematological disorders on bone marrow aspiration.
Hamzullah Khan +3 more
doaj
Nutritional assessment and serum zinc and copper concentration in leukemic children
São Paulo Medical Journal, 1999 CONTEXT: Malnutrition in childhood cancer is commonly a serious problem. Changes in blood zinc and copper have also been found in malignant diseases. OBJECTIVE: To describe the protein-energy nutritional status and serum zinc and copper of children with
Ursula Rohr Sgarbieri +2 more
doaj +1 more source