Results 121 to 130 of about 44,642 (305)

The t(5;14) chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 gene to the immunoglobulin heavy chain gene [PDF]

, 1989
J. Christopher Grimaldi, TC Meeker
openalex   +2 more sources

Evidence for distinct lymphocytic and monocytic populations in a patient with terminal transferase--positive acute leukemia [PDF]

, 1978
Roland Mertelsmann, Benjamín Koziner, R.K. Ralph, D Filippa, Susan McKenzie, Arlin Za, TS Gee, MA Moore, BD Clarkson   +8 more
openalex   +1 more source

Glucocorticoid Receptor Activation Reprograms NK Cells to Drive AREG‐Mediated Immunosuppression: A Pan‐Cancer Role for AREG

Advanced Science, EarlyView.
Natural killer cells, central to anti‐tumor defense, undergo unexpected reprogramming within the tumor microenvironment. Instead of producing IFN‐γ and TNF‐α, they elevate amphiregulin, a tumor‐promoting factor. This shift is linked to glucocorticoid receptor activity and prostaglandin signaling.
Qin Wei, Guirong Liang, Rui zeng, Yuancheng Li, Anlan Hong, Hongsheng Wang, Suying Feng, Yan Wang, Yetao Wang   +8 more
wiley   +1 more source

Variation in Survival Among Patients With Acute Lymphocytic Leukemia [PDF]

, 1971
Calvin Zippin, S. J. Cutler, William J. Reeves, Diana Lum   +3 more
openalex   +1 more source

AP2M1 Amplification Orchestrates Notch‐Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients

Advanced Science, EarlyView.
The precise regulation of AP2M1 is essential for normal hematopoiesis. Overexpression of AP2M1 negatively affects the clinical outcomes of AML patients. Upregulation of AP2M1 enhances stemness and chemoresistance in HSPC cells of AML. AP2M1 modulates NOTCH1 expression, enhancing the Notch1 signaling pathway.
Hansong Lee, Eun Kyoung Kim, Hee Young Ju, Chae Rin Lee, Soyul Ahn, Eun‐Sun Kim, Kyungjae Myung, Won Kyu Kim, Su‐Yeon Cho, Yujin Kwon, Dokyoung Kim, Yeuni Yu, Eun Jung Kwon, Hyomin Kim, Seong Ik Mun, Dong Min Lim, Kihun Kim, Hye Jin Heo, Seung Eun Baek, Sun Young Lee, Hyunsoo Cho, Eun Young Choi, Tae Sik Goh, Ninib Baryawno, Dongjun Lee, Ki Sun Jung, Keon Hee Yoo, Chang‐Kyu Oh, Yun Hak Kim   +28 more
wiley   +1 more source

Diagnosis Challenges in Adult Leukemia: Insights From a Single-Center Retrospective Study in Qatar (2016-2021)

Cancer Control
Objectives While delays in leukemia detection remain an ongoing challenge in hematologic cancer care, little is known about the factors associated with these delays.
Hesham A. B. Aboelkhir, Yousra El Alaoui MSc, Regina Padmanabhan PhD, Majed Hadid PhD, Adel Elomri PhD, Tanvir Alam PhD, Mohamed Amine Rejeb MBBS, Halima EL Omri MD, Ruba Y. Taha MD, Hesham Elsabah MD, Abdelfatteh EL Omri PhD   +10 more
doaj   +1 more source

Successful remission induction in children with acute lymphocytic leukemia at high risk for treatment failure [PDF]

, 1971
Rhomes J. A. Aur, Joseph V. Simone, Charles B. Pratt   +2 more
openalex   +1 more source

Enhancing Anti‐Tumor Effects of Engineered Extracellular Vesicles via Endocytosis Route Switching and Interferon Response Suppression

Advanced Science, EarlyView.
CD19‐293‐EV can switch the CD19 endocytosis pathway from clathrin‐mediated endocytosis to aggregation‐dependent endocytosis, leading to lysosomal degradation of the CD19/EVs complex. Degradation of the EVs leads to impairment in the IFN response and enhancement in EV uptake by target cells, creating a potent feedback cycle.
Zixuan Huang, Chaoqun Lu, Yixin Wang, Huajian Xian, Yuling Zheng, Ting Kang, Rufang Xiang, Shufeng Xie, Minghui Wang, Zeyi Li, Xiaoli Xia, Yaoyifu Yu, Wenjie Zhang, Huijian Zheng, Renyao Pan, Dan Li, Chunjun Zhao, Han Liu   +17 more
wiley   +1 more source

Current treatment strategies targeting histone deacetylase inhibitors in acute lymphocytic leukemia: a systematic review

Frontiers in Oncology
Acute lymphocytic leukemia is a hematological malignancy that primarily affects children. Long-term chemotherapy is effective, but always causes different toxic side effects.
Yingjun Zhang, Yingjun Zhang, Ge Zhang, Ge Zhang, Yuefang Wang, Yuefang Wang, Lei Ye, Lei Ye, Luyun Peng, Luyun Peng, Rui Shi, Rui Shi, Siqi Guo, Siqi Guo, Jiajing He, Jiajing He, Hao Yang, Hao Yang, Qingkai Dai, Qingkai Dai   +19 more
doaj   +1 more source

Serial In Vitro Bone Marrow Culture in Acute Lymphocytic Leukemia [PDF]

, 1973
M. Julian Duttera, J. M. C. Bull, John D. Northup, E. S. Henderson, Eleanor Stashick, Paul P. Carbone   +5 more
openalex   +1 more source