Results 131 to 140 of about 2,092,286 (303)

A Case of Hodgkin Transformation of Chronic Lymphocytic Leukemia

open access: yes, 2016
Richter’s transformation is a serious complication of chronic lymphocytic leukemia. We present a patient with Hodgkin transformation of chronic lymphocytic leukemia. This patient was admitted to our clinic with the complaints of weakness and fatigue. She
İlhami Kiki   +5 more
core   +1 more source

Tumour Antigen‐Specific Antibody Signatures as Diagnostic Biomarkers for Melanoma

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Early detection of melanoma remains challenging, and minimally invasive diagnostic tools are needed to complement imaging and histopathology. Circulating tumour antigen‐specific antibodies (Abs) are promising biomarkers, but their diagnostic value across melanoma stages is not fully established.
Cristina Vico‐Alonso   +4 more
wiley   +1 more source

Survival Rate of Patients with Acute Leukemia: A Case Study in Iran

open access: yesJournal of Evidence Based Health Policy, Management & Economics, 2020
Background: Acute leukemia is a kind of aggressive disease that includes high rates of fatalities in the world, in particular in Iran. This research was done to determine the survival rate of patients with acute leukemia in Iran.
Mohammad Ranjbar   +4 more
doaj  

Meta-analysis of the p53 codon 72 Arg>Pro polymorphism on leukemia risk.

open access: yes, 2012
aNumber of comparisons.bP value of Q-test for heterogeneity test.cOthers include acute lymphoblastic leukemia, chronic lymphocytic Leukemia, chronic myeloid leukemia.Abbreviations: AML, Acute myeloid leukemia.
Yu Weng (102970)   +7 more
core   +1 more source

Early Chidamide Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation in High‐Risk Myeloid Malignancies: A Prospective Cohort With Time‐Dependent External‐Control Analysis

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Chidamide is an oral histone deacetylase inhibitor whose use as early maintenance after allogeneic hematopoietic stem cell transplantation (HSCT) remains insufficiently defined. This prospective single‐center Phase 1/2 cohort included all 47 patients enrolled and treated by March 31, 2026.
Haonan Yang   +9 more
wiley   +1 more source

Metrnl: A Novel Therapeutic Target in Atherosclerosis

open access: yesiNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

Country‐Level Ecological Associations With Multiple Myeloma Prevalence and Death Rate: A Pan‐Database Study, 1990–2021

open access: yesiNew Medicine, EarlyView.
Using 18 global databases, this country‐level ecological study identified major positive and negative correlates of multiple myeloma prevalence and death rate, providing hypothesis‐generating evidence to inform future public health research and policy development.
Peng Xu   +8 more
wiley   +1 more source

SHP2 in Cancer: From Tumor Biology to Therapeutic Targeting

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT SHP2 is a tyrosine phosphatase that mediates intracellular signaling downstream of transmembrane receptors regulated by a pair of src homology 2 (SH2) domains. Its overexpression and mutation are pivotal in driving tumor progression by influencing various cancer's fundamental characteristics, such as metastasis, DNA repair, angiogenesis ...
Maryam Jama   +2 more
wiley   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde   +4 more
wiley   +1 more source

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