Results 121 to 130 of about 2,092,286 (303)

Old data, new tricks: Comprehensive computational analysis of 10 years of multi‐center EuroFlow acute myeloid leukemia diagnostic immunophenotypic data

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Acute myeloid leukemia (AML) is characterized by high genotypic and immunophenotypic heterogeneity. We collected an extensive dataset containing 5366 flow cytometry files from 885 AML patients, stained with the EuroFlow acute leukemia orientation tube (ALOT) and AML/MDS panel, acquired in a standardized way at eight centers over a period of 10 
Sarah Bonte, Rosan Olsman, Sofie Van Gassen, Sergio Matarraz, Neus Villamor, Stefan Nierkens, Paula Fernandez, Elaine Sobral da Costa, Carmen‐Mariana Aanei, Alberto Orfao, Jacques J. M. van Dongen, Yvan Saeys, Mattias Hofmans, Vincent H. J. van der Velden   +13 more
wiley   +1 more source

Extraction of dynamic patterns from static rna expression data: an application to hematological neoplasms [PDF]

, 2012
Within the study of pathological conditions from the analysis of high-throughput data, the usual approach consists in using supervised classification algorithms. Such approach frequently fails due to the initial bias of class definition uncertainty.
Bianchi, Giulia
core  

Subset‐specific and tissue‐specific expression of NK‐cell markers and killer immunoglobulin‐like receptors: Implications for NK‐cell clonality assessment

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate immunophenotypic evaluation of natural killer (NK)‐cell neoplasms is challenging because NK‐cells lack somatically rearranged antigen receptors, are comprised of phenotypically distinct subsets, and exhibit tissue‐specific subset distribution. We developed a flow cytometry (FC) panel for NK‐cell immunophenotypic analysis and clonality
Valerie Woodings, Orrin Koepke, Jason E. Love, Alireza Torabi, Lianqun Qiu, Jonathan R. Fromm, Sindhu Cherian, Afshin Shameli   +7 more
wiley   +1 more source

Clinical applications of CD34+ progenitor cell immunophenotyping in myelodysplastic neoplasms—The CytHem SMD French network experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Myelodysplastic neoplasms (MDS) are clonal hematopoietic disorders characterized by ineffective hematopoiesis, peripheral cytopenias, and a risk of progression to acute myeloid leukemia. As the disease originates in hematopoietic stem and progenitor cells (HSPCs), flow cytometry (FCM) has emerged as a key approach to interrogate the bone ...
Nicolas Chapuis, Anne‐Catherine Lhoumeau, Stéphanie Mathis, Michel Ticchioni, Valérie Bardet, the French Working Group CytHem‐SMD   +5 more
wiley   +1 more source

Harmonizing flow‐based quantification of CD19‐directed CAR‐T cells: Results from a multi‐center interlaboratory comparison

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract CD19‐directed CAR‐T cell therapy has become the standard of care for the treatment of relapsed/refractory LBCL, MCL, FL and BCP‐ALL. Expansion of CAR‐T cells in the peripheral blood (PB) of patients in the first weeks after infusion is an important biomarker for the prediction of therapy response and occurrence of toxicities.
Gerulf Hänel, Veit Bücklein, Carolina Berger, Anita Badbaran, Boris Fehse, Guranda Chitadze, Deniz Nogueira Gezer, Michael Hundemer, Wolfgang Kern, Sarah Klapproth, Ines Peschel‐Schaar, Christiane Siewert, Simon Völkl, Maria Xydia, Thomas Nebe, Michael Spannagl, Marion Subklewe   +16 more
wiley   +1 more source

Expressió de ZAP-70 en linfòcits B normals i síndromes limfoproliferatives B [PDF]

, 2006
[cat] La Leucèmia Limfàtica Crònica (LLC), la més freqüent de les leucèmies en el món occidental, és una malaltia produïda per la proliferació i cúmul de limfòcits B madurs, actualment incurable.
Crespo Maull, Marta
core   +1 more source

The Quality of Life of Patients With Different Leukemia Types

Journal of Client-centered Nursing Care, 2019
Background: Leukemia is among the major causes of mortality and disability and the seventh most prevalent cancer worldwide. It has various effects on the biopsychosocial, reproductive, and economic performance of individuals.
Hossein Poorcheraghi, Davood Hekmatpou, Fatemeh Mehrabi   +2 more
doaj  

Occupation and leukemia in Nordic countries

, 2012
We studied occupational variation of the risk of acute myeloid leukemia, chronic lymphocytic leukemia, and other leukemia in Nordic ...
Kjaerheim, Kristina, Weiderpass, E, Kautiainen, Susanna, Martinsen, JI, Lynge, E, Tryggvadottir, L, Kautiainen, S, Kautiainen, Susanna,, Sparen, Per, Weiderpass, Elisabete, Talibov, Madar, Martinsen, Jan Ivar,, Talibov, Madar,, Kjaerheim, Kristina,, Weiderpass, Elisabete,, Pukkala, Eero, Sparen, Per,, Lynge, Elsebeth,, Tryggvadottir, Laufey, Lynge, Elsebeth, Tryggvadottir, Laufey,, Sparen, P,, Kjaerheim, K, Pukkala, E, Talibov, M, Martinsen, Jan Ivar, Pukkala, Eero,   +26 more
core   +1 more source

Phytochemical Investigation and In Vitro Assessment of Antioxidant, Anti‐Inflammatory and Immunomodulatory Properties of Melia azedarach Linn. Extract in Chicken Lymphocyte Model

Flavour and Fragrance Journal, EarlyView.
Phytochemistry and biopotential of Melia azedarach Linn. ABSTRACT Melia azedarach Linn. (chinaberry), a medicinal plant native to tropical Asia, is a rich source of diverse bioactive compounds with reported pharmacological activities and promising therapeutic potential.
Priya Chand, Sonu Ambwani, Ravendra Kumar, Stefania Garzoli   +3 more
wiley   +1 more source

[Treatment of acute lymphocytic leukemia in adult].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 1989
Since April, 1978 to October, 1988, 66 acute lymphocytic leukemia (ALL) patients aged 15 to 79 (21 L1, 43 L2, 2 L3/6 Ph1+) were treated with 3 different therapeutic protocols. The drugs used for induction were VCR (VDS) + Pred, followed by DNR + VCR (VDS) + 6MP + Pred and VCR (VDS) + L-asp + Pred in protocol I, Ad + VCR + Pred in protocol II and DNR ...
TAKAHASHI, Isao, INAGAKI, Noritoshi, NAKADA, Hiroyuki, NISHIMURA, Masataka, HAYASHI, Naoki, SEKITO, Noriko, NONAKA, Kenichi, TAKEUCHI, Makoto, OSADA, Ken, MATUZAKI, Toshiro, FUKUDA, Shunichi, NAKAMURA, Tohru, MURASE, Toshio, KIMURA, Ikuro   +13 more
openaire   +2 more sources