Results 151 to 160 of about 44,642 (305)
Cytokine pathways driving diverse tissue pathologies in rheumatoid arthritis
Arthritis &Rheumatology, Accepted Article.Rheumatoid arthritis is a complex systemic disorder characterised primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease e.g. of the lung with potentially devastating clinical consequences.
Aurelie Najm +2 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis +5 more
wiley +1 more source
Monoclonal antibody OKT-9 recognizes the receptor for transferrin on human acute lymphocytic leukemia cells. [PDF]
, 1981 James W. Goding, G F Burns
openalex +1 more source
Mechanism and role of regulated cell death in tumor immunity and immunotherapy
Cancer Communications, EarlyView.Abstract Cancer immune checkpoint inhibitors (ICIs) have brought breakthroughs, but only about one‐third of cancer patients benefit from ICIs. In recent years, targeting non‐apoptotic regulated cell death (RCD) subtypes, such as ferroptosis, necroptosis, autophagy, cuproptosis, and pyroptosis, has emerged as a novel strategy in cancer therapy due to ...
Jingwen Hu +4 more
wiley +1 more source
Granulocytic Sarcoma as the First Sign of Acute Leukemia in Childhood [PDF]
, 2012 Acute myeloid leukemia (AML) may rarely involve the orbit as a solid tumor termed granulocytic sarcoma. This report describes the case of a child who presented with rapidly progressive unilateral proptosis and was diagnosed as rhabdomyosarcoma.
Singh, T, Sufi, AR
core +1 more source
Acute non-lymphocytic leukemia following multimodality therapy for retinoblastoma [PDF]
, 1985 Les White +2 more
openalex +1 more source
Breaking barriers: the cGAS‐STING pathway as a novel frontier in cancer immunotherapy
Cancer Communications, EarlyView.Abstract Since its discovery, the cyclic GMP‐AMP synthase (cGAS)‐stimulator of the interferon gene (STING) signaling pathway has been considered a pivotal component of innate immunity and a promising target for cancer immunotherapy. Beyond its canonical role in pathogen defense, accumulating evidence has demonstrated that the cGAS‐STING pathway ...
Yuheng Yan +5 more
wiley +1 more source
Sequential testicular biopsies in childhood acute lymphocytic leukemia [PDF]
, 1986 Tae Hyong Kim +6 more
openalex +1 more source
Cancer Communications, EarlyView.Abstract Background Third‐generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) show initial efficacy in EGFR‐mutated lung cancer, but residual disease persists. This study aimed to investigate cluster of differentiation 24 (CD24) as a translational immunotherapeutic target for enhancing third‐generation EGFR‐TKI efficacy.
Jiaqi Liang +16 more
wiley +1 more source