V-H gene usage differs in germline and mutated B-cell chronic lymphocytic leukemia [PDF]
Amlot, P +8 more
core
Intensive five-drug combination chemotherapy for adult acute non-lymphocytic leukemia
B. A. Peterson +4 more
openalex +1 more source
Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner +3 more
wiley +1 more source
A Case of Cardiac Chloroma Complicated by Acute Lymphocytic Leukemia [PDF]
Su Je Park +9 more
openalex +1 more source
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar +2 more
wiley +1 more source
Philadelphia chromosome positive acute lymphocytic leukemia arising from aplastic anemia [PDF]
Makoto Takeuchi +5 more
openalex +1 more source
Toward immunoprofiling in MDS: A computational study of the bone marrow immune microenvironment
Cytometry Part B: Clinical Cytometry, EarlyView.
Margot F. van Spronsen +6 more
wiley +1 more source
Body height and the excess cancer risk in men
What's New? In cancers that affect both sexes, men usually have a higher risk than women. While this is often attributed to behavioral factors, such as exposure to environmental carcinogens, there may be an intrinsic biological mechanism involved. Tall stature has been associated with increased cancer risk.
Cecilia Radkiewicz +6 more
wiley +1 more source
Diagnosis of unexpected acute myeloid leukemia and chronic lymphocytic leukemia: A case report demonstrating the perils of restricted panels in flow cytometric immunophenotyping [PDF]
Xiu Yan Xie +4 more
openalex +1 more source
Integrated scFv identification and CAR T cell generation for AML targeting in vivo
What's New? Acute myeloid leukemia (AML) is a rapidly progressing blood cancer. Advancing chimeric antigen receptor (CAR) T cell therapies, particularly through rapid translation of single chain variable fragment (scFv) discovery into CAR constructs, may improve clinical outcomes, especially the development of patient individualized CAR T cells.
Yi Liu +13 more
wiley +1 more source

