Results 191 to 200 of about 87,634 (337)

Engineering antibodies with cancer‐associated binding sites

BMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian, Yumeng Pan, Yingchun Zhang, Fangling Wang, Zejun Wang   +4 more
wiley   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu, Xu Zhang, Waner Liu, Zhe Zhou, Siyu Xiong, Jie Li, Xiang Chen, Cong Peng   +7 more
wiley   +1 more source

NAT10 regulates tumor progression and immune microenvironment in pancreatic ductal adenocarcinoma via the N4‐acetylated LAMB3‐mediated FAK/ERK pathway

Cancer Communications, EarlyView.
Abstract Background N‐acetyltransferase 10 (NAT10) was reported to be associated with the immune microenvironment in several cancers. However, it is not known in pancreatic ductal adenocarcinoma (PDAC). This study aimed to elucidate the roles and mechanisms of NAT10 in tumor malignancy and the tumor microenvironment (TME) in PDAC.
Enhong Chen, Qin Wang, Leisheng Wang, Zebo Huang, Dongjie Yang, Changyong Zhao, Wuqiang Chen, Shuo Zhang, Shuming Xiong, Youzhao He, Yong Mao, Hao Hu   +11 more
wiley   +1 more source

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Prognostic value and outcome for acute lymphocytic leukemia in children with MLL rearrangement: a case-control study. [PDF]

BMC Cancer, 2022
Qiu KY, Zhou DH, Liao XY, Huang K, Li Y, Xu HG, Weng WJ, Xu LH, Fang JP.   +8 more
europepmc   +1 more source

Growth factor-dependent differentiation along the myeloid and lymphoid lineages in an immature acute T lymphocytic leukemia. [PDF]

, 1990
Rosemary O’Connor, Alessandra Cesano, Brent Kreider, Beverly J. Lange, Stephen Clark, P C Nowell, J Finan, G Rovera, D Santoli   +8 more
openalex   +1 more source

Highly Sensitive and Disposable DNA‐Based Electrochemical Biosensor for Detection of Daunorubicin

ChemElectroChem, EarlyView.
Herin, a flower‐like porous MnO2‐modified pencil graphite electrode (MnO2‐PGE) is developed for the electrochemical determination of the anticancer drug daunorubicin and its interaction with dsDNA. The developed electrochemical nanobiosensor has some advantages, such as easy‐to‐handle, cost‐effective, portable, less time‐consuming assay and disposable.
Mukerrem Findik, Keziban Atacan, Emine Guler Akgemci   +2 more
wiley   +1 more source

Obstructive Jaundice as a Presenting Symptom of Acute Lymphocytic Leukemia in Adults: A Case Report. [PDF]

Cureus
Al-Shehab SM, El Saheb TK.
europepmc   +1 more source

1,5-Anhydroglucitol promotes pre-B acute lymphocytic leukemia progression by driving glycolysis and reactive oxygen species formation. [PDF]

BMC Cancer, 2023
Zhu H, Ma H, Dong N, Wu M, Li D, Liu L, Shi Q, Ju X.   +7 more
europepmc   +1 more source