Results 281 to 290 of about 351,966 (398)

A hybrid detection model for acute lymphocytic leukemia using support vector machine and particle swarm optimization (SVM-PSO). [PDF]

Sci Rep
Alsaykhan LK, Maashi MS.
europepmc   +1 more source

Electronic health records improve the diagnosis and prognosis of pulmonary fungal infections in lung cancer patients

VIEW, EarlyView.
Pulmonary fungal infections are life‐threatening complications in lung cancer patients, posing significant challenges in clinical management. To address this, we developed machine learning tools that translate routine electronic health record data into actionable insights for diagnosing infections and assessing prognosis.
Hongwei Meng, Jiayun Yang, Shouzhi Yang, Ayizekeranmu Yiming, Wenjun Yu, Yuewei Zhao, Chunmeng Ding, Kexin Meng, Si Gao, Yang Li, Nan Dan, Dandan Feng, Yunhua Xu, Lin Huang, Yongxia Qiao   +14 more
wiley   +1 more source

The Proteomics of T-Cell and Early T-Cell Precursor (ETP) Acute Lymphocytic Leukemia: Prognostic Patterns in Adult and Pediatric-ETP ALL. [PDF]

Cancers (Basel)
Hoff FW, Sriraja L, Qiu Y, Jenkins GN, Teachey DT, Wood B, Devidas M, Shockley S, Loh ML, Petsalaki E, Kornblau SM, Horton TM.   +11 more
europepmc   +1 more source

Single‐cell RNA sequencing revealed the T‐cell heterogeneity and exhaustion subsets of Helicobacter pylori‐induced gastritis‐to‐cancer transformation

VIEW, EarlyView.
H. pylori infection is a major cause of stomach cancer, but its effect on immune cells in tumors is unclear. Using single‐cell sequencing, we mapped the stomach tumor environment and discovered a specific exhausted T‐cell subtype, marked by the FYB1 gene, that is abundant in H. pylori‐positive tumors and linked to patient prognosis. Our findings reveal
Yanhui Yang, Yanxia Liu, Xiaole Guo, Zhaorun Li, Ziyu Liu, Shuming Zhang, Yuma Yang, Jun Liu, Shoucheng Ma, Linke Ma, Xianmei Chen, Xue Li, Yuanyuan Tang, Xiaoling Ding, Xiaofei Li, Qian Hao, Yanjie You, Tingting Yang, Qingrui Li, Xue Zhang, Sihan Zhang, Hengjun Gao, Shengjuan Hu   +22 more
wiley   +1 more source

Immunoprofiling Reveals GATA3 as a Prognostic Marker in Transformed Mycosis Fungoides

The Journal of Dermatology, EarlyView.
ABSTRACT Transformed mycosis fungoides (TMF) is a rare, aggressive variant of cutaneous T‐cell lymphoma characterized by the presence of large neoplastic cells and poor clinical outcomes. A retrospective cohort of 22 TMF patients was analyzed using immunohistochemistry on formalin‐fixed, paraffin‐embedded (FFPE) tissue for GATA3 (n = 20), T‐bet (n = 22)
Bruno de Castro e Souza, Denis Miyashiro, Jade Cury‐Martins, Neusa Yuriko Sakai Valente, Luiz Fernando Ferraz da Silva, José Antonio Sanches   +5 more
wiley   +1 more source

Augmented therapy improves outcome for pediatric high risk acute lymphocytic leukemia: Results of Children's Oncology Group trial P9906

Pediatric Blood & Cancer, 2011
W. Bowman, E. Larsen, M. Devidas, S. Linda, L. Blach, A. Carroll, W. Carroll, D. Pullen, J. Shuster, C. Willman, N. Winick, B. Camitta, S. Hunger, M. Borowitz   +13 more
semanticscholar   +1 more source

Long-Term Outcomes of Childhood Acute Lymphocytic Leukemia Treated with Adapted Berlin-Frankfurt-Münster (BFM) Protocols: A Multicentric Analysis from a Developing Country. [PDF]

Cancers (Basel)
Horn PRCB, Ribeiro-Carvalho MM, Azevedo AMB, Sousa AM, Faria S, Wiggers C, Rouxinol S, Schramm MT, Sanches BS, Duarte NL, Seixas TSF, Gomes BE, Oliveira E, Arcuri LJ, Costa ESD, Land MGP, Souza MHFO.   +16 more
europepmc   +1 more source

Clinical features and incidence of central nervous system involvement in patients with adult T‐cell leukaemia/lymphoma

British Journal of Haematology, EarlyView.
Summary Central nervous system (CNS) involvement is a known complication of adult T‐cell leukaemia/lymphoma (ATL), but its clinical characteristics and incidence still remain unclear. This study characterized the clinical features and incidence of CNS involvement in patients with ATL (CNS‐ATL).
Takuya Ueno, Makoto Yoshimitsu, Momone Sameshima, Taichi Nagano, Rika Akahoshi, Yusetsu Takeshita, Aya Shodai, Kodai Shima, Naosuke Arima, Yuhei Kamada, Daisuke Nakamura, Kenji Ishitsuka   +11 more
wiley   +1 more source

Genetic polymorphism association of HLA-G (G+3142 C>G, G*01:03, and G*01:05N) with acute lymphocytic leukemia in Saudi Arabia. [PDF]

Am J Transl Res
Al-Tamimi J, Al Omar SY, Aljuaimlani A, Mansour L.   +3 more
europepmc   +1 more source

Phase II study of the triple combination of rabbit ATG, ciclosporin and eltrombopag in patients with transfusion‐dependent aplastic anaemia: West Japan Hematology Study Group (W‐JHS) AA02 trial

British Journal of Haematology, EarlyView.
Summary The efficacy of a triple combination of rabbit anti‐human thymocyte immunoglobulin (rATG), ciclosporin and eltrombopag (EPAG) was prospectively evaluated in patients with severe or transfusion‐dependent non‐severe aplastic anaemia (SAA) across 29 institutions in Japan. Sixty patients were enrolled, of whom 48 had SAA. The primary end‐point, the
Fumi Nakamura, Ken Ishiyama, Ritsuro Suzuki, Hiroyuki Maruyama, Yasushi Onishi, Kensuke Usuki, Hideo Koh, Katsuto Takenaka, Ryunosuke Saiki, Seishi Ogawa, Kana Matsumoto, Takuto Takahashi, Kazuyoshi Hosomichi, Yoshitaka Zaimoku, Kenichi Yoshimura, Itaru Matsumura, Koichi Akashi, Shinji Nakao   +17 more
wiley   +1 more source