Results 51 to 60 of about 5,904 (121)
Gomal Journal of Medical Sciences, 2018 Background: Bone marrow aspiration is a diagnostic test for various hematological malignancies. Present study was designed to determine the frequency of malignant Hematological disorders on bone marrow aspiration.
Hamzullah Khan +3 more
doaj
Journal of Medical Case Reports, 2009 Introduction An increase in circulating lymphocytes can be seen following infections such as infectious mononucleosis and pertussis, or in lymphoproliferative disorders such as acute and chronic lymphocytic leukemia.
Plastiras Sotiris, Kampessi Ourania
doaj +1 more source
Journal of Baghdad College of Dentistry, 2014 Background: Leukemia is a broad term given to a group of malignant diseases characterized by diffuse replacement of bone marrow with proliferating leukocyte precursors. Chemotherapy has been increasingly used to treat malignant conditions.
Nadia A Al-Rawi +2 more
doaj
Nutritional assessment and serum zinc and copper concentration in leukemic children
São Paulo Medical Journal, 1999 CONTEXT: Malnutrition in childhood cancer is commonly a serious problem. Changes in blood zinc and copper have also been found in malignant diseases. OBJECTIVE: To describe the protein-energy nutritional status and serum zinc and copper of children with
Ursula Rohr Sgarbieri +2 more
doaj +1 more source
A mathematical model for chemoimmunotherapy of chronic lymphocytic leukemia [PDF]
arXiv, 2018 Immunotherapy is currently regarded as the most promising treatment to fight against cancer. This is particularly true in the treatment of chronic lymphocytic leukemia, an indolent neoplastic disease of B-lymphocytes which eventually causes the immune system's failure.
arxiv
Inferring clonal evolution of tumors from single nucleotide somatic mutations [PDF]
arXiv, 2012 High-throughput sequencing allows the detection and quantification of frequencies of somatic single nucleotide variants (SNV) in heterogeneous tumor cell populations. In some cases, the evolutionary history and population frequency of the subclonal lineages of tumor cells present in the sample can be reconstructed from these SNV frequency measurements.
arxiv
A Nonconventional Analysis of CD$4^{+}$ and CD$8^{+}$ T Cell Responses During and After Acute Lymphocytic Choriomeningitis Virus Infection [PDF]
arXiv, 2017 A mathematical model from a previous work was re-fitted and analyzed for experimental data regarding the cellular immune response to the lymphocytic choriomeningitis virus. Specifically, the $CD8^{+}$ T cell response to six MHC class I-restricted epitopes (GP* and NP*) and $CD4^{+}$ T cell responses to two MHC class II-restricted epitopes\cite ...
arxiv
The Topology of Mutated Driver Pathways [PDF]
arXiv, 2019 Much progress has been made, and continues to be made, towards identifying candidate mutated driver pathways in cancer. However, no systematic approach to understanding how candidate pathways relate to each other for a given cancer (such as Acute myeloid leukemia), and how one type of cancer may be similar or different from another with regard to their
arxiv
Childhood acute lymphocytic leukemia. Study VIII [PDF]
, 1978 Rhomes J. A. Aur +10 more
openalex +1 more source
Chromatin Redistribution of the DEK Oncoprotein Represses hTERT Transcription in Leukemias
Neoplasia: An International Journal for Oncology Research, 2014 Although numerous factors have been found to modulate hTERT transcription, the mechanism of its repression in certain leukemias remains unknown. We show here that DEK represses hTERT transcription through its enrichment on the hTERT promoter in cells ...
Maroun Karam +14 more
doaj +1 more source