Results 61 to 70 of about 38,858 (94)
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Chronic Lymphocytic Leukemia Terminating in Acute Leukemia
Archives of Internal Medicine, 1977The occurrence of acute leukemia in patients with chronic lymphocytic leukemia is being reported with increasing frequency. 1-31 Although the majority of these cases have been described as "acute blastic terminal phase" or as straightforward lymphoblastic in nature, a substantial number of patients' terminal acute leukemia has been described as ...
Hans W. Grünwald +2 more
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Apoptosis and Acute Lymphocytic Leukemia in Children
Annals of the New York Academy of Sciences, 1997We examined in vivo spontaneous and prednisolone-induced apoptosis in peripheral blood samples of 23 children with ALL by flow cytometric and morphologic methods. There was no significant spontaneous apoptosis before the therapy. Six hours after prednisolone therapy, increased apoptosis was found in 19 of 23 cases.
Schuler, Dezső, Szende, Béla
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Relapsed acute lymphocytic leukemia
Current Oncology Reports, 2008Introduction: Acute lymphocytic leukemia (ALL) is the most common cancer found in children. It accounts for 25% of all childhood cancers in patients younger than 21 years old in the United States [1]. About 2400 children, adolescents, and young adults develop ALL in the United States each year.
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Chromosomes in acute lymphocytic leukemia
Cancer Genetics and Cytogenetics, 1987Results of chromosome analysis in acute lymphocytic leukemia are reviewed. Emphasis is placed on so-called specific translocations and their association with cytology, immunology, and prognosis. Data presently available suggest that chromosomes in acute lymphocytic leukemia are not only an important, independent prognostic factor, but also contribute ...
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Immunotherapy for Acute Lymphocytic Leukemia [PDF]
, 2010 While a majority of patients with acute lymphocytic leukemia (ALL) demonstrate response following treatment with standard chemotherapy, subsequent progression due to the emergence of resistant disease is often encountered. The failure to eradicate disease is most commonly observed in adult patients particularly with high-risk features such as adverse ...
David Avigan, Jacalyn Rosenblatt
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Treatment of Childhood Acute Lymphocytic Leukemia
The Journal of Pediatrics, 1970Thank you for the honor of sharing in this memorial to Frederick Stohlman. The work I will report today represents the efforts of many physicians and scientists who have tried to understand and control childhood leukemia.
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Dermatoglyphics and Acute Lymphocytic Leukemia in Children
Journal of Pediatric Oncology Nursing, 1991Cellular features of acute lymphocytic leukemia (ALL) in children suggest that it originates in abnormal embryogenesis. Because palmar flexion creases develop in the embryo at the same time as the blood-forming cells, and because both arise from mesodermal tissue, insults to the embryo that may lead to leukemic changes in the blood-forming cells may ...
Michael D. Amylon +2 more
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PATHOLOGIC DIAGNOSIS OF ACUTE LYMPHOCYTIC LEUKEMIA
Hematology/Oncology Clinics of North America, 2000With present knowledge, the optimal management of individual patients with acute leukemia requires that every case be studied by morphology, cytochemistry, cytogenetic, immunologic and molecular techniques. An algorithm for diagnostic evaluation and classification of ALL is provided in Fig. 11.
Carlos E. Bueso-Ramos +2 more
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Emerging drugs for acute lymphocytic leukemia
Expert Opinion on Emerging Drugs, 2013Acute lymphoblastic leukemia (ALL) is typically treated with complex multi-agent chemotherapy regimens over a prolonged time period. Long-term outcomes depend on the age of the patient and the biological characteristics of the leukemic cells. While pediatric patients achieve cure more often than adults, therapy can continue to be improved for all ...
Michael S. Mathisen +2 more
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Acute transformation of chronic lymphocytic leukemia
Medical and Pediatric Oncology, 1984AbstractA patient with chronic lymphocytic leukemia had typical cell morphology and a characteristic clinical course for 7 years. He then developed progressive disease with a rapidly rising WBC which proved resistant to chemotherapy. The cells resembled lymphoblasts.
Andrew D. Jacobs +2 more
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