Results 91 to 100 of about 22,427 (199)

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

L-lactate in acute mesenteric ischemia: a reliable biomarker for diagnosis and prognosis?

Emergency Care Journal
Acute mesenteric ischemia is a life-threatening condition with high mortality, often caused by arterial or venous hypoperfusion of the intestines.
Rıza Deryol, Duray Şeker, Gaye Ebru Şeker, Şener Balas   +3 more
doaj   +1 more source

Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies

MedComm, Volume 7, Issue 10, October 2026.
The schematic representation of intrinsic and extrinsic influences of cancer cell metastasis. Genomic evolution of metastatic tumor cells (MTCs) promotes their metastatic phenotypes and reconstruct the primary tumor microenvironment. During MTCs migration along different routes (blood circulation, lymphatic vessels, and perineuronal spaces), the ...
Yupeng Zhao, Wenchao Xu, Yibo Wang, Haoran Huang, Yu Su, Li Zhou, Jianzhou Liu, Junchao Guo   +7 more
wiley   +1 more source

Network Biology: Current Status, Applications, Challenges, and Future Prospects

MedComm, Volume 7, Issue 10, October 2026.
Network biology integrates molecular interaction, intracellular regulatory, single‐cell and multicellular, microbial and host–microbiome, disease, and interorgan networks across biological scales. Perturbation models, multiomics, spatial profiling, computational inference, mechanistic modeling, and AI enable dynamic network reconstruction and causal ...
Xinmeng Li, Laizhong Zhang, Yawen Ding, Kai Li, Shiyuan Chang, Linsen Pei, Zhengwei Li, Zhenzhen Chen   +7 more
wiley   +1 more source

Gastrointestinal adverse effects of GLP‐1 receptor agonists and dual GIP/GLP‐1 receptor agonists: A narrative expert review of approved therapies, oral formulations, and pipeline agents

Nutrition in Clinical Practice, Volume 41, Issue 5, Page 1318-1333, October 2026.
Abstract Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and dual glucose‐dependent insulinotropic polypeptide (GIP)/GLP‐1 receptor agonists have transformed the management of type 2 diabetes and obesity. Gastrointestinal (GI) adverse events are the most common limitation of these therapies and a leading cause of discontinuation ...
Vikash Singhani, Muhammad Ehsan, Sara Valencia, Ahmed Nadeem, Eisha Moazzam, Winfield Scott Butsch, Samita Garg   +6 more
wiley   +1 more source

Immunomodulatory Properties of Withania somnifera: Regulation of Innate Immune Cells and Clinical Implications

Phytotherapy Research, Volume 40, Issue 10, Page 5951-5972, October 2026.
ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta, Sonalika Gupta, Gagandeep Kaur, Partha Sarathi Mondal, Milirani Das, Anagha Ranade, Alok Kumar Srivastava, Sachin Kumar, Manoj Kumar Barthwal, Madhu Dikshit   +9 more
wiley   +1 more source

Ūminė mezenterinė išemija po širdies operacijos

Lietuvos Chirurgija, 2010
Judita Andrejaitienė Kauno medicinos universiteto Biomedicininių tyrimų institutas, Intensyviosios terapijos ir kraujotakos tyrimų laboratorija, KMU BMTI Intensyviosios terapijos ir kraujotakos tyrimo laboratorija, Eivenių g.
Judita Andrejaitienė
doaj  

Extended D3 Mesenterectomy in Small Bowel Cancer Treatment: Feasibility and Importance for Staging. First Results of a Prospective Clinical Trial

World Journal of Surgery, Volume 50, Issue 10, Page 2996-3007, October 2026.
There is no consensus on surgical techniques in small bowel cancer, particularly regarding the extent of lymph node dissection and strategic choices according to tumor localization and histological type. Clearance of central lymph node metastases can be challenging, especially when small intestinal neuroendocrine tumor (siNET) metastases give rise to ...
Erik Kjæstad, Espen Thiis‐Evensen, Bjørn Edwin, Arne Olav Bakka, Anne Helene Lilleaas, Yngve Thorsen, Johannes Kurt Schultz   +6 more
wiley   +1 more source

Mitochondrial Fusion and Fission in Age‐Related Cardio‐Cerebral Diseases: Mechanisms and Interventions

Aging Cell, Volume 25, Issue 10, October 2026.
Mitochondrial fission‐fusion imbalance contributes to age‐related cardio‐cerebral diseases like Alzheimer's disease, Parkinson's disease, Cerebral Infarction, Arteriosclerosis, Myocardial Infarction, Cardiac valve disease, Hypertension, and Cardiomyopathy. This review summarizes its regulatory mechanisms and interventions.
Yuyao Yin, Zijian Li
wiley   +1 more source

Exercise and Autonomic Cardiovascular Function—Insights From Spinal Cord‐Injured Humans: A Narrative Review

Acta Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT The cardiovascular response to acute exercise is mediated by the autonomic nervous system (ANS) control mechanisms that modulate vascular resistance to support blood pressure and ensure adequate blood flow to active muscles. These autonomic neurocirculatory control mechanisms include a feedforward mechanism, known as central command, and three
Rasmus Kopp Hansen, Ryan Godsk Larsen, Tom E. Nightingale, Daniel D. Hodgkiss, Niels H. Secher, Stefanos Volianitis   +5 more
wiley   +1 more source