Results 71 to 80 of about 135,603 (277)

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu, Wenjing Xian, Mengxue Wang, Guozhi Zhao, Yanhuo Zhang, Zhiyu Zhou, Bo Sheng, Zhuo Zhen, Xie Liu, Shouwen Diao, Mengwei Tu, Chen Qiu, Huixian Wang, Jianbo Zhang, Peng Zhu, Tong Li   +15 more
wiley   +1 more source

Epithelial TRIM27 Inhibits Intestinal Inflammation in Ulcerative Colitis by the USP7/TRIM27‐IKK Double Negative‐Feedback

Advanced Science, EarlyView.
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu, Zhebin Hua, Zhujiang Dai, Shasha Zhang, Yihan Jiang, Wensong Ge, YingWei Chen, Zhongchuan Wang, Bing Zhang, Chen‐Ying Liu, Peng Du   +10 more
wiley   +1 more source

Post traumatic arterial occlusive mesenteric ischemia: a rare case report

Radiology Case Reports, 2022
Mesenteric ischemia is an uncommon condition with very high mortality rates characterized by inadequate blood supply, inflammatory injury, and subsequent necrosis of the bowel wall.
Khalid Khan, MBBS, CABR, Fatema Bunajem, MD, Fatema Alkhan, MD   +2 more
doaj   +1 more source

The route and timing of hydrogen sulfide therapy critically impacts intestinal recovery following ischemia and reperfusion injury [PDF]

, 2018
PURPOSE: Hydrogen sulfide (H2S) has many beneficial properties and may serve as a novel treatment in patients suffering from intestinal ischemia-reperfusion injury (I/R).
Drucker, Natalie A., Ferkowicz, Michael J., Jensen, Amanda R., Markel, Troy A., te Winkel, Jan P.   +4 more
core   +1 more source

Psoas Muscle Volume as a Predictor of Postoperative Complications in Patients Undergoing Emergency Surgery for Strangulated Small Bowel Obstruction: A Retrospective Single‐Center Study

Annals of Gastroenterological Surgery, EarlyView.
This retrospective study identified low preoperative psoas muscle volume, measured by computed tomography, as an independent predictor of postoperative complications in patients undergoing emergency surgery for strangulated small bowel obstruction. Low psoas muscle volume, particularly in older adults, was associated with cardiopulmonary and systemic ...
Takuya Shiraishi, Chika Katayama, Yuta Shibasaki, Chika Komine, Takuhisa Okada, Akihiko Sano, Makoto Sakai, Hiroomi Ogawa, Ken Shirabe, Hiroshi Saeki   +9 more
wiley   +1 more source

Predicting Outcomes in Patients With Atrial Fibrillation and Acute Mesenteric Ischemia

Journal of Patient-Centered Research and Reviews, 2016
Purpose: Outcomes in patients with atrial fibrillation who develop acute mesenteric ischemia, and the impact of anticoagulation on complications, are not defined.
Sanjay Bhandari, Geetanjali Dang, Muhammad Shahreyar, Ahmad Hanif, Vijayadershan Muppidi, Atul Bhatia, Jasbir Sra, A. Jamil Tajik, Arshad Jahangir   +8 more
doaj   +1 more source

An intriguing autopsy case of gangrene intestine [PDF]

, 2006
Background Hashimoto’s thyroiditis is one of the most common causes of hypothyroidism. Hypothyroidism is a known cause of hyperlipidemia. There is a strong correlation between coronary and mesenteric vessel atherosclerosis.
E., E.Jayashankar, Patnayak, Rashmi Patnayak, Prayaga, Aruna K. Prayaga, Reddy, Rajasekhar Reddy, S.V.N., S.V.N. Anuradha   +4 more
core  

Reappraisal of Real‐World Management of Acute Cholecystitis in Elderly Patients Based on the Adherence to Tokyo Guidelines 2018 (TG18): A Multicenter Study on Anzu HPB Surgical Meeting

Annals of Gastroenterological Surgery, EarlyView.
This multicenter retrospective study analyzes real‐world management of acute cholecystitis in patients aged ≥ 70 years across five institutions, focusing on adherence and intentional deviation from TG18 recommendations. By classifying treatment strategies as TG18‐accordant, more aggressive, or more conservative, we reappraise current practice patterns.
Yuta Kobayashi, Shojiro Hata, Ryo Oikawa, Tetsuya Nakazato, Hiroki Sakata, Hirokazu Yamaguchi, Yutaka Suzuki, Yoshihiro Sakamoto   +7 more
wiley   +1 more source

Abdominal Angina Treated by Urgent Percutaneous Angioplasty: An Excellent Alternative to Surgical Revascularisation [PDF]

Journal of Clinical and Diagnostic Research, 2016
Chronic Mesenteric Ischemia (CMI) presenting as acute abdomen can be treated percutaneously. An endovascular intervention has surpassed surgical revascularization over the past decade due to its lesser perioperative complication rate.
Vamsi Krishna Kamana, Ranjan Shetty, Anand M Krishnan, M Sudhakar Rao, Umesh Pai Malpe   +4 more
doaj   +1 more source

Direct Peritoneal Resuscitation Improves Mesenteric Perfusion by Nitric Oxide Dependent Pathways [PDF]

, 2017
Background Direct peritoneal resuscitation (DPR) has been shown to increase survival after intestinal ischemia and reperfusion injury (I/R). We have previously appreciated that minimum essential medium (MEM), a synthetic cell culture medium with ...
Drucker, Natalie A., Jensen, Amanda R., Khaneki, Sina, Markel, Troy A.   +3 more
core   +1 more source