Results 31 to 40 of about 13,673 (189)

In Situ Photo‑Crosslinked Functional Bilayer Hydrogel Modulates Local Microenvironment and Remyelination After Optic Nerve Injury

Advanced Science, EarlyView.
A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan, Yate Huang, Junhao Zhang, Shudong Tian, Zhixing Li, Xuanwen Li, Yanchen Zhang, Dongmei Wang, Sihao Ye, Ming Jin, Neng Ling, Wentao Yan, Kaihui Nan, Wencan Wu   +13 more
wiley   +1 more source

Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded Murine ATXN3

Annals of Neurology, EarlyView.
Repeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Juan P. Mato, John M. Hayes, Jacen Emerson, Maeha Sridharan, Toluwani Adelaja, Arsal Naeem, Alexandra F. Putka, Hayley S. McLoughlin   +7 more
wiley   +1 more source

Finger drop sign—Characteristic pattern of distal weakness in Guillain-Barré Syndrome: A case report and review of the literature

SAGE Open Medical Case Reports, 2018
Guillain-Barré Syndrome is an acquired acute autoimmune polyradiculoneuropathy that commonly presents with limb weakness and occasional cranial nerve, respiratory and autonomic involvement.
Yong Chuan Chee, Beng Hooi Ong
doaj   +1 more source

Neurosarcoidosis camouflaging as partial miller: Fisher syndrome

Indian Journal of Rheumatology, 2023
Neurological involvement in sarcoidosis has varied presentations. Peripheral neuropathy is one of them. Symmetrical axonal type sensory-motor polyneuropathy is the most common form; focal and multifocal neuropathy, polyradiculopathy, and vascular ...
B N Shiva Prasad, Subramanian Ramaswamy, Aumir Moin, Srinivas Nalloor   +3 more
doaj   +1 more source

Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients

Annals of Neurology, EarlyView.
Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer, Seth Frietze, Serena W.R. Lewis, Emily C. Artman, Christina Coughlan, Safa I. Vaseemuddin, Arianna Gentile Polese, Maria A. Nagel, Stephen K. Tyring, Fyona Okundia, Anthony J. Saviola, Gary C. Curhan, Sharon G. Curhan, Diego Restrepo, Andrew N. Bubak   +14 more
wiley   +1 more source

Acute myeloneuropathy: An uncommon presentation of Sjögren′s syndrome

Annals of Indian Academy of Neurology, 2013
Sjögren′s syndrome is associated with central and peripheral nervous system involvement. The peripheral neuropathy is usually a sensory predominant neuropathy or a cranial neuropathy.
Rajesh Verma, Rakesh Lalla, Tushar B Patil, Vinod Mehta   +3 more
doaj   +1 more source

Biallelic PIGB Variants Cause Motor Neuropathy with Conduction Blocks and Peripheral Nerve Hyperexcitability

Annals of Neurology, EarlyView.
Objective Glycosylphosphatidylinositol (GPI)‐anchored proteins play critical roles in nervous system function. Pathogenic variants in genes involved in GPI‐anchor biosynthesis cause early‐onset multisystem disorders known as inherited GPI deficiencies. We describe a novel neuromuscular phenotype associated with PIGB deficiency.
Gorka Fernández‐Eulate, Romain Duval, Marina Konyukh, Alessandro Bertini, Ayse Candayan, Albena Jordanova, Theresa Brunet, Wolfgang Müller‐Felber, Helena F. Pernice, Katrin Hahn, Nadja Ehmke, Juliane Beuschlein, Bertrand Isidor, Benjamin Cogné, Yann Péréon, Annabelle Chaussenot, John Rendu, Aysylu Murtazina, Dmitrii Subbotin, Artem Borovikov, Andrey Marakhonov, Chiara Pisciotta, Paola Saveri, Daniele Cazzato, Lucie Lemeray, Bérengère Koehl, Jean‐Madeleine de Sainte‐Agathe, Stefano Facchini, Ilaria Quartesan, Andrea Cortese, Yesim Parman, Arman Cakar, Davide Pareyson, Slim Azouzi, Tanya Stojkovic   +34 more
wiley   +1 more source

FREQUENCY OF AXONAL VARIANTS OF GUILLAIN-BARRÉ SYNDROME IN PAKISTAN

Pakistan Armed Forces Medical Journal, 2011
Objective: To determine the frequency of axonal variants in our patients of Guillain-Barre Syndrome. Study Design: Descriptive study. Place and Duration: Department of Neurology, Military Hospital, Rawalpindi and Armed Forces Institute of Rehabilitation
Muhamamd Babar Khan, Waseem Wali Muhammad, Khuram Haq Nawaz, Imran Ahmad, Muhammad Ali Yousaf,, Nadeem Ahmad, Farooq Azam Rathore, Khalil Ahmad   +7 more
doaj   +2 more sources

Electrophysiologic findings in patients with COVID-19 and quadriparesia in the northwest of Iran, A case series study and literature review

Caspian Journal of Internal Medicine, 2021
Background: As a global health pandemic, the novel severe acute respiratory syndrome-coronavirus 2 (SARS- CoV2) outbreak began in December 2019 which rapidly spread to more than 200 countries.
Fariba Eslamian, Negar Taleschian-Tabrizi, Behzad Izadseresht, Seyyed Kazem Shakouri, Shakiba Gholian, Mohammad Rahbar   +5 more
doaj  

Long-term Disability and Poor Outcome Predictors of Guillain-Barre Syndrome in Children: A Systematic Review [PDF]

Journal of Pediatrics Review, 2023
Background: Guillain-Barre syndrome (GBS) is an immune-mediated polyneuropathy and a common cause of acute ascending weakness in children.  Objectives: This study aims to report long-term disability and poor outcome predictors of GBS in children. Medline
Vahideh Toopchizadeh, Mohammad Barzegar, Negar Taleschian-Tabrizi, Fariba Pashazadeh, Nasim Rashedi, Masood Chahvechi-Akbari, Ozra Noori   +6 more
doaj