Results 101 to 110 of about 5,530 (227)
Brain strain: Blood flow and metabolism in environmental extremes
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak +3 more
wiley +1 more source
Abstract Sympathetic nervous system activation is a hallmark of high‐altitude hypoxia, yet the afferent mechanisms remain incompletely defined. We examined the relative contributions of pulmonary arterial mechanoreceptors and carotid chemoreceptors – two excitatory pathways co‐activated by hypoxia – to sustained sympathoexcitation at altitude.
Michiel T. Ewalts +13 more
wiley +1 more source
Abstract Hypoxaemia occurs in intermittent forms, such as obstructive sleep apnoea, and in continuous forms, such as at high altitude, and is increasingly recognized as a modulator of cardiometabolic risk. Although hypoxaemia alters postprandial glucose and lipid metabolism, its effects on ketone bodies remain unclear.
Nicholas Goulet +6 more
wiley +1 more source
Acute mountain sickness is a pathologic reaction as a result of bad adaptation to high altitudes (greater than 2.500 meters). The main symptoms are headache, nausea, vomits, and insomnia. When severe it can produce oliguria, retinal hemorrhage, ataxia and sometimes coma. Its etiology is not well known. It is considered that the first producer factor of
A, Guijarro Morales +2 more
openaire +1 more source
Abstract figure legend This randomized cross‐over trial (N = 12) addressed the hypothesis that selective reduction of pulmonary arterial pressure (i.e. manipulation of pulmonary arterial mechanoreceptor activation) during hypoxic exercise would reduce sympathetic outflow (muscle sympathetic nerve activity (MSNA)) in healthy humans.
Michiel T. Ewalts +9 more
wiley +1 more source
Abstract figure legend Schematic overview of the randomised crossover study investigating the effects of nocturnal periodic breathing (nPB) on sympathetic activity and ventilatory acclimatisation in hypobaric hypoxia equivalent to 4000 m altitude. Participants completed two 3‐day sojourns where nPB was inhibited by increasing inspiratory CO2 fraction ...
Johanna Roche +13 more
wiley +1 more source
Abstract figure legend To investigate age‐related differences in ventilatory and cerebrovascular responses to exercise at high‐altitude, adults (n = 10, 23–44 years) and children (n = 8, 7–14 years) completed progressive cycling exercise tests at sea‐level and following 6 days of acclimatization at 3800 m.
J. L. Koep +11 more
wiley +1 more source
Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?
Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley +1 more source
Abstract figure legend This study aimed to develop a non‐invasive method for visualizing the cardiorespiratory network under baseline conditions and following isolated or combined exposure to hypoxia, exercise, and sleep deprivation. Twenty‐two healthy participants underwent assessments at rest and after normobaric hypoxia (FIO2${{F}_{{\mathrm{I ...
Cecilia Morandotti +10 more
wiley +1 more source

