Results 1 to 10 of about 20,539 (219)

Acetazolamide: Old drug, new evidence? [PDF]

open access: yesEpilepsia Open, 2022
Acetazolamide is an old drug used as an antiepileptic agent, amongst other indications. The drug is seldom used, primarily due to perceived poor efficacy and adverse events. Acetazolamide acts as a noncompetitive inhibitor of carbonic anhydrase, of which
Norman Delaney   +2 more
exaly   +5 more sources

Transient myopia induced by acetazolamide in a pregnant patient with idiopathic intracranial hypertension: A case of successful rechallenge [PDF]

open access: yesAmerican Journal of Ophthalmology Case Reports
Background: Acetazolamide is the mainstay of treatment for idiopathic intracranial hypertension (IIH). Transient myopia is a rare ocular adverse effect, usually attributed to ciliary body edema and forward displacement of the lens–iris diaphragm.
Luai Eldweik
doaj   +2 more sources

GC-NICI-MS analysis of acetazolamide and other sulfonamide (R-SO2-NH2) drugs as pentafluorobenzyl derivatives [R-SO2-N(PFB)2] and quantification of pharmacological acetazolamide in human urine

open access: yesJournal of Pharmaceutical Analysis, 2020
Acetazolamide (molecular mass (MM), 222) belongs to the class of sulfonamides (R-SO2-NH2) and is one of the strongest pharmacological inhibitors of carbonic anhydrase activity. Acetazolamide is excreted unchanged in the urine.
Dimitrios Tsikas, Georgios Theodoridis
exaly   +3 more sources

The effect of acetazolamide on sleep apnea at high altitude: a systematic review and meta-analysis

open access: yesTherapeutic Advances in Respiratory Disease, 2017
Background: Acetazolamide has been investigated for treating sleep apnea in newcomers ascending to high altitude. This study aimed to assess the effect of acetazolamide on sleep apnea at high altitude, determine the optimal therapeutic dose, and compare ...
Hsin-Ming Liu   +2 more
exaly   +2 more sources

Acetazolamide-Induced Bilateral Uveal Effusions and Secondary Angle Closure: A Case Report [PDF]

open access: yesCase Reports in Ophthalmology
Introduction: Acetazolamide-induced uveal effusion and secondary angle closure is a rarely reported but clinically significant phenomenon. The reaction is idiosyncratic and independent of dosage or prior exposure.
Kaela Braue   +2 more
doaj   +2 more sources

Efficacy of acetazolamide for the prophylaxis of acute mountain sickness: A systematic review, meta-analysis, and trial sequential analysis of randomized clinical trials

open access: yesAnnals of Thoracic Medicine, 2021
BACKGROUND: Acute mountain sickness (AMS) is a benign and self-limiting syndrome, but can progress to life-threatening conditions if leave untreated.
Daiquan Gao   +3 more
doaj   +1 more source

Acetazolamide-Induced Ciliochoroidal Effusion In A Patient With Pseudoexfoliation Glaucoma

open access: yesDelhi Journal of Ophthalmology, 2021
Aim: We describe a male patient, with Pseudoexfoliation glaucoma who developed bilateral ciliochoroidal effusions after Acetazolamide ingestion. Observations: Our patient was referred from a local health centre with history of ocular pain, redness and ...
Marushka Aguiar   +3 more
doaj   +1 more source

Acetazolamide prevents hypoxia‐induced reactive oxygen species generation and calcium release in pulmonary arterial smooth muscle

open access: yesPulmonary Circulation, 2021
Upon sensing a reduction in local oxygen partial pressure, pulmonary vessels constrict, a phenomenon known as hypoxic pulmonary vasoconstriction. Excessive hypoxic pulmonary vasoconstriction can occur with ascent to high altitude and is a contributing ...
Larissa A. Shimoda   +6 more
doaj   +1 more source

Acute Hemodynamic Effect of Acetazolamide in Patients With Pulmonary Hypertension Whilst Breathing Normoxic and Hypoxic Gas: A Randomized Cross-Over Trial

open access: yesFrontiers in Medicine, 2021
Aims: To test the acute hemodynamic effect of acetazolamide in patients with pulmonary hypertension (PH) under ambient air and hypoxia.Methods: Patients with pulmonary arterial or chronic thromboembolic PH (PAH/CTEPH) undergoing right heart ...
Mona Lichtblau   +12 more
doaj   +1 more source

Population pharmacodynamic modeling and simulation of the respiratory effect of acetazolamide in decompensated COPD patients. [PDF]

open access: yesPLoS ONE, 2014
Chronic obstructive pulmonary disease (COPD) patients may develop metabolic alkalosis during weaning from mechanical ventilation. Acetazolamide is one of the treatments used to reverse metabolic alkalosis.619 time-respiratory (minute ventilation, tidal ...
Nicholas Heming   +7 more
doaj   +1 more source

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