Results 1 to 10 of about 844 (97)

GC-NICI-MS analysis of acetazolamide and other sulfonamide (R-SO2-NH2) drugs as pentafluorobenzyl derivatives [R-SO2-N(PFB)2] and quantification of pharmacological acetazolamide in human urine

Journal of Pharmaceutical Analysis, 2020
Acetazolamide (molecular mass (MM), 222) belongs to the class of sulfonamides (R-SO2-NH2) and is one of the strongest pharmacological inhibitors of carbonic anhydrase activity. Acetazolamide is excreted unchanged in the urine.
Olga Begou, Georgios Theodoridis, Dimitrios Tsikas   +2 more
exaly   +3 more sources

The effect of acetazolamide on sleep apnea at high altitude: a systematic review and meta-analysis

Therapeutic Advances in Respiratory Disease, 2017
Background: Acetazolamide has been investigated for treating sleep apnea in newcomers ascending to high altitude. This study aimed to assess the effect of acetazolamide on sleep apnea at high altitude, determine the optimal therapeutic dose, and compare ...
Hsin-Ming Liu, Ken N Kuo, Cher-Ming Liou   +2 more
exaly   +2 more sources

Acetazolamide: Old drug, new evidence?

Epilepsia Open, 2022
Acetazolamide is an old drug used as an antiepileptic agent, amongst other indications. The drug is seldom used, primarily due to perceived poor efficacy and adverse events. Acetazolamide acts as a noncompetitive inhibitor of carbonic anhydrase, of which
Arif Shukralla, Emma Dolan, Norman Delanty   +2 more
exaly   +2 more sources

Efficacy of acetazolamide for the prophylaxis of acute mountain sickness: A systematic review, meta-analysis, and trial sequential analysis of randomized clinical trials

Annals of Thoracic Medicine, 2021
BACKGROUND: Acute mountain sickness (AMS) is a benign and self-limiting syndrome, but can progress to life-threatening conditions if leave untreated.
Daiquan Gao, Yuan Wang, Rujiang Zhang, Yunzhou Zhang   +3 more
doaj   +1 more source

Acetazolamide-Induced Ciliochoroidal Effusion In A Patient With Pseudoexfoliation Glaucoma

Delhi Journal of Ophthalmology, 2021
Aim: We describe a male patient, with Pseudoexfoliation glaucoma who developed bilateral ciliochoroidal effusions after Acetazolamide ingestion. Observations: Our patient was referred from a local health centre with history of ocular pain, redness and ...
Marushka Aguiar, Naomi Desiree D’Costa, Ugam, P.S. Usgaonkar   +3 more
doaj   +1 more source

Acetazolamide prevents hypoxia‐induced reactive oxygen species generation and calcium release in pulmonary arterial smooth muscle

Pulmonary Circulation, 2021
Upon sensing a reduction in local oxygen partial pressure, pulmonary vessels constrict, a phenomenon known as hypoxic pulmonary vasoconstriction. Excessive hypoxic pulmonary vasoconstriction can occur with ascent to high altitude and is a contributing ...
Larissa A. Shimoda, Karthik Suresh, Clark Undem, Haiyang Jiang, Xin Yun, J.T. Sylvester, Erik R. Swenson   +6 more
doaj   +1 more source

Acute Hemodynamic Effect of Acetazolamide in Patients With Pulmonary Hypertension Whilst Breathing Normoxic and Hypoxic Gas: A Randomized Cross-Over Trial

Frontiers in Medicine, 2021
Aims: To test the acute hemodynamic effect of acetazolamide in patients with pulmonary hypertension (PH) under ambient air and hypoxia.Methods: Patients with pulmonary arterial or chronic thromboembolic PH (PAH/CTEPH) undergoing right heart ...
Mona Lichtblau, Charlotte Berlier, Stéphanie Saxer, Arcangelo F. Carta, Laura Mayer, Alexandra Groth, Patrick R. Bader, Simon R. Schneider, Michael Furian, Esther I. Schwarz, Erik R. Swenson, Konrad E. Bloch, Silvia Ulrich   +12 more
doaj   +1 more source

Population pharmacodynamic modeling and simulation of the respiratory effect of acetazolamide in decompensated COPD patients. [PDF]

PLoS ONE, 2014
Chronic obstructive pulmonary disease (COPD) patients may develop metabolic alkalosis during weaning from mechanical ventilation. Acetazolamide is one of the treatments used to reverse metabolic alkalosis.619 time-respiratory (minute ventilation, tidal ...
Nicholas Heming, Saïk Urien, Virginie Fulda, Ferhat Meziani, Arnaud Gacouin, Marc Clavel, Benjamin Planquette, Christophe Faisy   +7 more
doaj   +1 more source

Effects of acetazolamide on linear growth in children with pseudotumor cerebri syndrome

Frontiers in Ophthalmology, 2023
Background/introductionWhile oral acetazolamide is a cornerstone of management of adult and pediatric PTCS, previous studies have suggested that acetazolamide used in children with other conditions may influence growth.Aims and methodsRetrospective chart
Claire A. Sheldon, Sara N. Reggie, Grace L. Paley, Shana E. McCormack, Grant T. Liu   +4 more
doaj   +1 more source

Effect of Acetazolamide on Obesity-Induced Glomerular Hyperfiltration: A Randomized Controlled Trial. [PDF]

PLoS ONE, 2015
Obesity is an important risk factor for the development of chronic kidney disease. One of the major factors involved in the pathogenesis of obesity-associated kidney disease is glomerular hyperfiltration.
Boris Zingerman, Michal Herman-Edelstein, Arie Erman, Sarit Bar Sheshet Itach, Yaacov Ori, Benaya Rozen-Zvi, Uzi Gafter, Avry Chagnac   +7 more
doaj   +1 more source