Results 31 to 40 of about 20,539 (219)

Acetazolamide-based fungal chitinase inhibitors [PDF]

, 2010
Chitin is an essential structural component of the fungal cell wall. Chitinases are thought to be important for fungal cell wall remodelling, and inhibition of these enzymes has been proposed as a potential strategy for development of novel anti-fungals.
Gros, Ludovic, van Aalten, Daan M. F., Schuettelkopf, Alexander W., David E. Blair, van Aalten, Daan M.F., Blair, David E., Frearson, Julie A., Schüttelkopf, Alexander W., Daan M.F. van Aalten, Ian H. Gilbert, Gilbert, Ian H., Julie A. Frearson, Alexander W. Schüttelkopf, Ludovic Gros   +13 more
core   +1 more source

Dissociation of Vasoreactivity to Acetazolamide and Hypercapnia [PDF]

, 1996
Background and Purpose The aim of this study was to compare the effect of vasodilative stimuli for the measurement of cerebrovascular reactivity obtained by acetazolamide and hypercapnia in patients with chronic occlusive major ...
Tatsuya Ishikawa, Naruhiko Tanaka, Kenji Mitsumori, Ken Kazumata, Satoshi Kuroda, Kiyohiro Houkin   +5 more
core   +1 more source

Growth Suppression with Acetazolamide [PDF]

, 1997
The effect of acetazolamide on growth of children with epilepsy was evaluated at Osaka Medical Center ...
J Gordon Millichap
core   +1 more source

Acetazolamide Attenuates Lithium-Induced Nephrogenic Diabetes Insipidus [PDF]

, 2015
To reduce lithium-induced nephrogenic diabetes insipidus (lithium-NDI), patients with bipolar disorder are treated with thiazide and amiloride, which are thought to induce antidiuresis by a compensatory increase in prourine uptake in proximal tubules ...
Groot, T. de, Wetzels, J.F.M., Deen, P.M.T., Wetzels, Jack F, Olivier Devuyst, Mohammad Alsady, Deen, Peter M T, Sinke, Anne P, Baumgarten, Ruben, de Groot, Theun, Devuyst, Olivier, Devuyst, O., Marleen L.A. Kortenoeven, Kortenoeven, M.L.A., Johannes Loffing, Kortenoeven, Marleen L A, Sinke, A.P., Alsady, M., Loffing, J., Anne P. Sinke, Jack F. Wetzels, Ruben Baumgarten, Loffing, Johannes, Alsady, Mohammad, Theun de Groot, Peter M.T. Deen, Baumgarten, R.   +26 more
core   +1 more source

Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Neisseria gonorrhoeae is a high-priority pathogen of concern due to the growing prevalence of resistance development against approved antibiotics. Herein, we report the anti-gonococcal activity of ethoxzolamide, the FDA-approved human carbonic anhydrase ...
Nader S. Abutaleb, Ahmed E. M. Elhassanny, Alessio Nocentini, Chad S. Hewitt, Ahmed Elkashif, Bruce R. Cooper, Claudiu T. Supuran, Mohamed N. Seleem, Daniel P. Flaherty   +8 more
doaj   +1 more source

Effects of acetazolamide on control of breathing in sleep apnea patients: Mechanistic insights using meta‐analyses and physiological model simulations

Physiological Reports, 2021
Obstructive and central sleep apnea affects ~1 billion people globally and may lead to serious cardiovascular and neurocognitive consequences, but treatment options are limited.
Christopher N. Schmickl, Shane Landry, Jeremy E. Orr, Brandon Nokes, Bradley A. Edwards, Atul Malhotra, Robert L. Owens   +6 more
doaj   +1 more source

Cerebrovascular reserve in moyamoya disease: relation to cerebral blood flow, capillary dysfunction, oxygenation, and energy metabolism

Frontiers in Neurology, 2023
BackgroundCerebral hemodynamics in moyamoya disease (MMD) is complex and needs further elucidation. The primary aim of the study was to determine the association of the cerebrovascular reserve (CVR) with cerebral blood flow (CBF) disturbances, oxygen ...
Teodor Svedung Wettervik, Markus Fahlström, Johan Wikström, Anders Lewén, Per Enblad   +4 more
doaj   +1 more source

Acetazolamide and high altitude diseases [PDF]

, 1992
Acetazolamide is a useful prophylactic for acute mountain sickness causing marked reduction in headache, nausea, vomiting, weakness, etc. Improvements correlate with increased arterial oxygen concentrations, reduction in proteinuria and peripheral oedema
Imray, C. (Chris), Bradwell, A., Winterborn, M., Wright, A.   +3 more
core   +1 more source

Acetazolamide poisoning in a toddler [PDF]

, 2001
Acetazolamide ingestion and its sequelae have not been previously reported in children. A 12-month-old girl, weighing 10 kg, developed metabolic acidosis following ingestion of between 500 and 1250 mg of acetazolamide.
Baer, E., Reith, D. M., E Baer, DM Reith
core   +1 more source

Cerebral Blood Flow Alteration by Acetazolamide During Carotid Balloon Occlusion [PDF]

, 1996
Background and Purpose We attempted to clarify the role of the acetazolamide-reactive mechanism in cerebral hemodynamic autoregulation and to establish a useful method of estimation using the acetazolamide test.
Hajime Arai, Kiyoshi Sato, Yojiro Okudaira   +2 more
core   +1 more source