Results 21 to 30 of about 16,449 (190)

Acetazolamide induced noncardiogenic pulmonary edema, an underreported serious adverse event

American Journal of Ophthalmology Case Reports, 2023
Purpose: To report a case of acute noncardiogenic pulmonary edema (NCPE) after administration of acetazolamide post routine cataract surgery. Observations: 30 minutes after administration of oral acetazolamide, the patient experienced abdominal pain ...
Andrew H. Schwartz, Sandra Sieminski
doaj   +1 more source

Structural and Vibrational Study on Monomer and Dimer Forms and Water Clusters of Acetazolamide

Journal of Spectroscopy, 2013
Experimental IR and Raman spectra of solid acetazolamide have been analysed by computing the molecular structures and vibrational spectra of monomer and dimer forms and water clusters of acetazolamide. The possible stable conformers of free acetazolamide
Aysen E. Ozel, Serda Kecel Gunduz, Sefa Celik, Sevim Akyuz   +3 more
doaj   +1 more source

Acetazolamide for Bipolar Disorders: A Scoping Review

Brain Sciences, 2023
Acetazolamide, a carbonic anhydrase inhibitor, is used to treat a variety of ailments. It has been highlighted for its potential to benefit people with bipolar disorders, for whom there are clear current unmet treatment needs.
Rebecca Strawbridge, Nefize Yalin, Stelios Orfanos, Allan H. Young   +3 more
doaj   +1 more source

Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Neisseria gonorrhoeae is a high-priority pathogen of concern due to the growing prevalence of resistance development against approved antibiotics. Herein, we report the anti-gonococcal activity of ethoxzolamide, the FDA-approved human carbonic anhydrase ...
Nader S. Abutaleb, Ahmed E. M. Elhassanny, Alessio Nocentini, Chad S. Hewitt, Ahmed Elkashif, Bruce R. Cooper, Claudiu T. Supuran, Mohamed N. Seleem, Daniel P. Flaherty   +8 more
doaj   +1 more source

Cerebrovascular reserve in moyamoya disease: relation to cerebral blood flow, capillary dysfunction, oxygenation, and energy metabolism

Frontiers in Neurology, 2023
BackgroundCerebral hemodynamics in moyamoya disease (MMD) is complex and needs further elucidation. The primary aim of the study was to determine the association of the cerebrovascular reserve (CVR) with cerebral blood flow (CBF) disturbances, oxygen ...
Teodor Svedung Wettervik, Markus Fahlström, Johan Wikström, Anders Lewén, Per Enblad   +4 more
doaj   +1 more source

Effects of acetazolamide on control of breathing in sleep apnea patients: Mechanistic insights using meta‐analyses and physiological model simulations

Physiological Reports, 2021
Obstructive and central sleep apnea affects ~1 billion people globally and may lead to serious cardiovascular and neurocognitive consequences, but treatment options are limited.
Christopher N. Schmickl, Shane Landry, Jeremy E. Orr, Brandon Nokes, Bradley A. Edwards, Atul Malhotra, Robert L. Owens   +6 more
doaj   +1 more source

Effect of 5 weeks of oral acetazolamide on patients with pulmonary vascular disease: A randomized, double-blind, cross-over trial

Pulmonology
Background The carbonic anhydrase inhibitor acetazolamide stimulates ventilation through metabolic acidosis mediated by renal bicarbonate excretion. In animal models, acetazolamide attenuates acute hypoxia-induced pulmonary hypertension (PH), but its ...
M. Lichtblau, S. Saxer, J. Müller, P. Appenzeller, C. Berlier, S.R. Schneider, L. Mayer, M. Furian, E.I. Schwarz, E.R. Swenson, K.E. Bloch, S. Ulrich   +11 more
doaj   +1 more source

Efficacy of Acetazolamide in Refractory Epilepsy Management: A Quasi-Experimental Study

Pakistan Armed Forces Medical Journal, 2023
Objective: To assess the efficacy of Acetazolamide in refractory epilepsy management. Study Design: Quasi-experimental study. Place and Duration of Study: Outpatient Neurology Department, Allied Hospital, Faisalabad Pakistan, from Sep 2020 to Feb ...
Muhammad Ahmed Zamir, Naveed Alam, Javed Iqbal, Muhammad Ali Rehman, Baqar Raza   +4 more
doaj   +1 more source

Idiopathic Intracranial Hypertension Is Characterized by a Distinct Proteomic Profile

Annals of Neurology, EarlyView.
Objectives The pathophysiology of idiopathic intracranial hypertension (IIH) is poorly understood and disease‐specific biomarkers are lacking. We aimed to shed light on IIH pathophysiology and identify disease‐specific biomarkers. Methods This prospective cross‐sectional cohort study included patients with new‐onset IIH and age‐, body mass index‐, and ...
Santosh D. Bhosale, Arkadiusz Nawrocki, Johanne J. Korsbæk, Nadja S. Hansen, Fabian Foettinger, Nik Krajnc, Mathias J. Norvig, Niclas L. Eriksen, Stefan Macher, Berthold Pemp, Connar S.J. Westgate, Christian B. Pedersen, Frantz R. Poulsen, Sune Munthe, Gabriel Bsteh, Martin R. Larsen, Rigmor H. Jensen, Dagmar Beier   +17 more
wiley   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source