Results 21 to 30 of about 22,683 (182)

The Effects of Acetazolamide on Cerebral Hemodynamics in Adult Patients with an Acute Brain Injury: A Systematic Review

Brain Sciences, 2023
Background: Acetazolamide is a non-competitive inhibitor of carbonic anhydrase, an enzyme expressed in different cells of the central nervous system (CNS) and involved in the regulation of cerebral blood flow (CBF).
Claudia Stella, Anas Hachlouf, Lorenzo Calabrò, Irene Cavalli, Sophie Schuind, Elisa Gouvea Bogossian, Fabio Silvio Taccone   +6 more
doaj   +1 more source

Acetazolamide Intoxication in an Elderly Patient with Diabetes and Chronic Renal Failure after Cataract Surgery

Case Reports in Critical Care, 2020
Carbonic anhydrase inhibitors, such as acetazolamide, are widely used in the treatment of open-angle glaucoma. Severe metabolic acidosis is a rare complication of acetazolamide use, and life-threatening acidosis occurs most commonly in elderly patients ...
Juliana Maria Kerber, Juliana Dias de Mello, Karolinny Borinelli de Aquino Moura, Gustavo Cardoso da Silva, Iuri Christmann Wawrzeniak, Tatiana Helena Rech   +5 more
doaj   +1 more source

The effects of acetazolamide on physiological variables among adolescents at high altitude [PDF]

Sport Sciences and Health Research, 2021
Background: High altitude environments can cause a range of physiological changes in the body, and adolescents may be particularly vulnerable to the effects of altitude sickness.
Govindasamy Balasekaran, Sarah Thompson, Visvasuresh Victor Govindaswamy, Yew Cheo Ng   +3 more
doaj   +1 more source

Should I Stay or Should I Go—Leveraging an Overlooked Feature of Click‐to‐Release Chemistry for Affinity Labeling

Angewandte Chemie, EarlyView.
Click‐to‐release (C2R) chemistry is redirected from payload liberation toward ligand‐directed covalent protein labeling through a transient dihydropyridazine methide (DHP‐methide). This concept opens the way to dual‐functional systems combining covalent target engagement with controlled effector release.
Dóra Kern, Krisztina Németh, Tímea Imre, József Simon, Kitti Meggyes, Gergő Bárdos, László Petri, Márton Bojtár, Attila Kormos, Péter Kele   +9 more
wiley   +2 more sources

Structural and Vibrational Study on Monomer and Dimer Forms and Water Clusters of Acetazolamide

Journal of Spectroscopy, 2013
Experimental IR and Raman spectra of solid acetazolamide have been analysed by computing the molecular structures and vibrational spectra of monomer and dimer forms and water clusters of acetazolamide. The possible stable conformers of free acetazolamide
Aysen E. Ozel, Serda Kecel Gunduz, Sefa Celik, Sevim Akyuz   +3 more
doaj   +1 more source

Acetazolamide-induced bilateral uveal effusion after cataract surgery

TNOA Journal of Ophthalmic Science and Research, 2023
Idiosyncratic reactions to a large number of drugs have been reported to cause choroidal detachment and secondary angle-closure glaucoma (ACG). We report a case of bilateral acute ACG and peculiar choroidal effusion following the administration of oral ...
Abhinay Ashok, Manoj Y Bhat, Rashmi Shetty   +2 more
doaj   +1 more source

Physiology of lived experience: The struggles of my first experience of sleep at 3810 m [PDF]

Exp Physiol
Experimental Physiology, EarlyView.
Bommarito J.
europepmc   +2 more sources

Therapeutic impact of lumbar puncture versus acetazolamide in idiopathic intracranial hypertension [PDF]

Romanian Journal of Neurology
Idiopathic intracranial hypertension (IIH), also known as pseudotumor cerebri, is a neurological syndrome characterized by elevated intracranial pressure (ICP) of unknown cause.
Raad Ahmed Hussein, Rana Hani Mohammed Ali Al-Shaikh Hamed, Muhammed Hameed Faeadh Hsn Al Jumaily   +2 more
doaj   +1 more source

Cerebrovascular reserve in moyamoya disease: relation to cerebral blood flow, capillary dysfunction, oxygenation, and energy metabolism

Frontiers in Neurology, 2023
BackgroundCerebral hemodynamics in moyamoya disease (MMD) is complex and needs further elucidation. The primary aim of the study was to determine the association of the cerebrovascular reserve (CVR) with cerebral blood flow (CBF) disturbances, oxygen ...
Teodor Svedung Wettervik, Markus Fahlström, Johan Wikström, Anders Lewén, Per Enblad   +4 more
doaj   +1 more source

Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Neisseria gonorrhoeae is a high-priority pathogen of concern due to the growing prevalence of resistance development against approved antibiotics. Herein, we report the anti-gonococcal activity of ethoxzolamide, the FDA-approved human carbonic anhydrase ...
Nader S. Abutaleb, Ahmed E. M. Elhassanny, Alessio Nocentini, Chad S. Hewitt, Ahmed Elkashif, Bruce R. Cooper, Claudiu T. Supuran, Mohamed N. Seleem, Daniel P. Flaherty   +8 more
doaj   +1 more source