Cytarabine plus idarubicin or daunorubicin as induction and consolidation therapy for previously untreated adult patients with acute myeloid leukemia [PDF]
Wiernik Ph+8 more
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This study identifies STAU2 as an oncogenic RNA‐binding protein (RBP) with elevated expression in pancreatic ductal adenocarcinoma (PDAC), where its high levels are significantly correlated with metastatic progression. It elucidates that STAU2 directly binds and regulates PALLD, while mediating the functional role of IQGAP1, thereby driving metastasis ...
Jiayu Ding+16 more
wiley +1 more source
Acute myeloid leukemia complicated with tuberculosis.
Keiko Morikawa, Yoko Niki, H Hoshizaki
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The balanced and the unbalanced chromosome aberrations of acute myeloid leukemia may develop in different ways and may contribute differently to malignant transformation [PDF]
J Pedersen-Bjergaard, JD Rowley
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This review comprehensively examines the applications of protein three‐dimensional structures and artificial intelligence in investigating drug synergistic and antagonistic effects. The research findings provide compelling evidence for the precision treatment of cancer and metabolic diseases, thereby promoting the development of personalized medicine ...
Anqi Lin+11 more
wiley +1 more source
Characterization of childhood acute leukemia with multiple myeloid and lymphoid markers at diagnosis and at relapse [see comments] [PDF]
C-H Pui+7 more
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Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei+10 more
wiley +1 more source
Recombinant human granulocyte-macrophage colony-stimulating factor after chemotherapy in patients with acute myeloid leukemia at higher age or after relapse [PDF]
Th. Büchner+9 more
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In ESCC patients, SNORA58 exhibits heterogeneous expression patterns. Its aberrant overexpression stabilizes CTCF by inhibiting ubiquitin‐mediated degradation, leading to the attenuation of JNK1‐mediated ferroptosis induced by radiotherapy through disruption of intracellular iron homeostasis, and ultimately contributes to radioresistance ...
Yinli Zheng+14 more
wiley +1 more source
Detection of chimeric BCR-ABL genes on bone marrow samples and blood smears in chronic myeloid and acute lymphoblastic leukemia by in situ hybridization [PDF]
Martin Bentz+6 more
openalex +1 more source