Clonal Analysis of Multiple Point Mutations in the N‐ras Gene in Patients with Acute Myeloid Leukemia [PDF]
, 1993 Kazuaki Kubo +9 more
openalex +1 more source
Randomization in phase II trials: No exemption based on sample size
British Journal of Clinical Pharmacology, EarlyView.Conducting randomized clinical trials (RCTs) is challenging. For this reason, in earlier phases of drug development and rare diseases with limited sample sizes, there is a tendency to omit control groups and to replace them with historical information for perceived feasibility arguments.
Theodor Framke +4 more
wiley +1 more source
No increase of leukemia relapse in newly diagnosed patients with acute myeloid leukemia who received granulocyte colony-stimulating factor for life-threatening infection during remission induction and consolidation therapy. Japan Adult Leukemia Study Group [letter] [PDF]
, 1993 R Ohno +9 more
openalex +1 more source
Engineering antibodies with cancer‐associated binding sites
BMEMat, EarlyView.This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian +4 more
wiley +1 more source
The WWP1-JARID1B axis sustains acute myeloid leukemia chemoresistance. [PDF]
Proc Natl Acad Sci U S AFierro C +19 more
europepmc +1 more source
Synergistic reversal of multidrug-resistance phenotype in acute myeloid leukemia cells by cyclosporin A and cremophor EL [PDF]
, 1994 DD Ross +7 more
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Neuroleukemiosis Masquerading as Drug Toxicity in an Adolescent With Refractory AML
American Journal of Hematology, EarlyView.
Nia Choi +11 more
wiley +1 more source
Cancer Communications, EarlyView.Abstract Background Overweight and obesity are known risk factors for cancer. The aim of this study was to investigate associations of body mass index (BMI) and waist circumference (WC) with incidence of 27 site‐specific cancers stratified by sex and menopausal status accounting for non‐linearity.
Seonghye Kim +7 more
wiley +1 more source
Involvement of the MLL/ALL-1 gene associated with multiple point mutations of the N-ras gene in acute myeloid leukemia with t(11;17)(q23;q25) [letter] [PDF]
, 1993 Tomoki Naoe +8 more
openalex +1 more source