Results 101 to 110 of about 1,066,380 (380)

The heartbreak of depression: 'Psycho-cardiac' coupling in myocardial infarction [PDF]

, 2017
Ample evidence identifies strong links between major depressive disorder (MDD) and both risk of ischemic or coronary heart disease (CHD) and resultant morbidity and mortality. The molecular mechanistic bases of these linkages are poorly defined. Systemic
Budiono, Boris P, Headrick, John P., Neumann, David L., Peart, Jason N., Shum, David H K, Stapelberg, Nicolas J C   +5 more
core   +1 more source

Bivalirudin during primary PCI in acute myocardial infarction.

New England Journal of Medicine, 2008
BACKGROUND Treatment with the direct thrombin inhibitor bivalirudin, as compared with heparin plus glycoprotein IIb/IIIa inhibitors, results in similar suppression of ischemia while reducing hemorrhagic complications in patients with stable angina and ...
G. Stone, B. Witzenbichler, G. Guagliumi, J. Peruga, B. Brodie, Dariusz Dudek, R. Kornowski, Franz Hartmann, B. J. Gersh, S. Pocock, G. Dangas, S. C. Wong, Ajay J. Kirtane, H. Parise, R. Mehran   +14 more
semanticscholar   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

Advanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail, Vincent O. Nyandoro, Calvin A. Omolo, Thirumala Govender   +3 more
wiley   +1 more source

Trends in Clinical, Demographic, and Biochemical Characteristics of Patients with Acute Myocardial Infarction from 2003 to 2008: A Report from the American Heart Association Get with the Guidelines Coronary Artery Disease Program [PDF]

, 2012
Background: An analysis of the changes in the clinical and demographic characteristics of patients with acute myocardial infarction could identify successes and failures of risk factor identification and treatment of patients at increased risk for ...
Bhatt, Deepak L., Boyer, Nathan M., Cannon, Christopher Paul, Cox, Margueritte, Fonarow, Gregg C., Hernandez, Adrian F., Laskey, Warren K., Peterson, Eric D.   +7 more
core   +1 more source

Ischemia/Reperfusion Injury following Acute Myocardial Infarction: A Critical Issue for Clinicians and Forensic Pathologists

Mediators of Inflammation, 2017
Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality. Reperfusion strategies are the current standard therapy for AMI. However, they may result in paradoxical cardiomyocyte dysfunction, known as ischemic reperfusion injury (IRI)
M. Neri, I. Riezzo, Natascha Pascale, C. Pomara, E. Turillazzi   +4 more
semanticscholar   +1 more source

Ultra‐Tiny Gelatin Nanoparticles‐Assisted 3D Stem Cell Spheroids for Engineering Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
GNPs effectively guide the formation of structurally compact and functionally enhanced stem cell spheroids. This GNP‐assisted 3D culture system improves cell–cell and cell‐ECM interactions, leading to superior viability and complexity. Time‐dependent regenerative potential is demonstrated in both bone and skin defects, positioning GNP‐spheroids as a ...
Dream Kim, Woochan Kim, Harshita Sharma, Shinyull Lee, Chaeyeon Park, Sunho Park, Chan Yeong Heo, Jangho Kim   +7 more
wiley   +1 more source

Multicenter Evaluation of a 0-Hour/1-Hour Algorithm in the Diagnosis of Myocardial Infarction With High-Sensitivity Cardiac Troponin T [PDF]

, 2016
Study objectiveWe aim to prospectively validate the diagnostic accuracy of the recently developed 0-h/1-h algorithm, using high-sensitivity cardiac troponin T (hs-cTnT) for the early rule-out and rule-in of acute myocardial infarction.MethodsWe enrolled ...
Bendig, Garnet, Body, Richard, Christ, Michael, Christenson, Robert, Defilippi, Christopher, Dilba, Peter, Dolci, Alberto, French, John, Giannitsis, Evangelos, Horner, Daniel, Jarausch, Jochen, Jernberg, Tomas, Katus, Hugo A., Lindahl, Bertil, Manara, Alessandro, McCord, James, Menassanch-Volker, Sylvie, Mueller, Christian, Nowak, Richard M., Ordoñez Llanos, Jorge, Panteghini, Mauro, Plebani, Mario, Popp, Steffen, Santalo-Bel, Miquel, Twerenbold, Raphael, Universitat Autònoma de Barcelona, Verschuren, Franck, Weiser, Silvia, Zaninotto, Martina, Zaugg, Christian   +29 more
core   +1 more source

Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction.

New England Journal of Medicine, 2006
BACKGROUND Pilot trials suggest that the intracoronary administration of autologous progenitor cells may improve left ventricular function after acute myocardial infarction.
V. Schächinger, S. Erbs, A. Elsässer, W. Haberbosch, R. Hambrecht, H. Hölschermann, Jiangtao Yu, R. Corti, D. Mathey, C. Hamm, T. Süselbeck, B. Assmus, T. Tonn, S. Dimmeler, A. Zeiher   +14 more
semanticscholar   +1 more source

Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction

Advanced Materials, EarlyView.
The heart organoid model exhibits the acidic microenvironment characteristic of myocardial infarction, which emerges as a pivotal force propelling the movement of micro‐robots. These micro‐robots, administered through microneedles, can penetrate deep into the tissue, effectively delivering therapeutic payloads to facilitate heart repair.
Fangfang Wang, Zilu Xu, Feiyang Zheng, Dongcheng Yang, Kaige Xu, Ming Ke, Xiao Zhou, Xiaohan Zhang, Ju Tan, Yong Liu, Yansha Hao, Malcolm Xing, Chuhong Zhu   +12 more
wiley   +1 more source

Complete left bundle branch block as predictor of cardiogenic shock in patient with acute myocardial infarction on the background of diabetes mellitus type 2

Актуальні проблеми сучасної медицини, 2020
Cardiogenic shock is the leading cause of death in patients with acute myocardial infarction, with high hospital mortality rates ∼80 %. The incidence of cardiogenic shock among myocardial infarction patients is approximately 7 %.
Olena Makharynska, Nataliia Bogun, Irina Oktiabrova, Эке Міракл Чиамака   +3 more
doaj   +1 more source