Results 11 to 20 of about 5,536,395 (362)

Selective Inhibition of NaV1.8 with VX-548 for Acute Pain.

New England Journal of Medicine, 2023
BACKGROUND The NaV1.8 voltage-gated sodium channel, expressed in peripheral nociceptive neurons, plays a role in transmitting nociceptive signals. The effect of VX-548, an oral, highly selective inhibitor of NaV1.8, on control of acute pain is being ...
Jim Jones, D. Correll, S. Lechner, Ina Jazic, Xiaopeng Miao, David Shaw, Christopher Simard, Jeremiah D. Osteen, Brian Hare, Alina Beaton, Todd Bertoch, A. Buvanendran, Ashraf S Habib, L. Pizzi, R. Pollak, S. Weiner, C. Bozic, PaulA . Negulescu, P. White   +18 more
semanticscholar   +1 more source

Cultural Framing and the Impact On Acute Pain and Pain Services

Current Pain and Headache Reports, 2023
Optimal treatment requires a thorough understanding of all factors contributing to pain in the individual patient. In this review, we investigate the influence of cultural frameworks on pain experience and management.
Rahel Rogger, Corina M. Bello, C. Romero, R. Urman, M. Luedi, Mark G. Filipovic   +5 more
semanticscholar   +1 more source

Multimodal physiological sensing for the assessment of acute pain

Frontiers in Pain Research, 2023
Pain assessment is a challenging task encountered by clinicians. In clinical settings, patients’ self-report is considered the gold standard in pain assessment. However, patients who are unable to self-report pain are at a higher risk of undiagnosed pain.
Raul Fernandez Rojas, Niraj Hirachan, Nicholas Brown, G. Waddington, Luke Murtagh, B. Seymour, Roland Goecke   +6 more
semanticscholar   +1 more source

Acupuncture Therapy as an Evidence-Based Nonpharmacologic Strategy for Comprehensive Acute Pain Care: The Academic Consortium Pain Task Force White Paper Update

Pain medicine (Malden, Mass.), 2022
Background A crisis in pain management persists, as does the epidemic of opioid overdose deaths, addiction, and diversion. Pain medicine is meeting these challenges by returning to its origins: the Bonica model of multidisciplinary pain care.
A. Nielsen, J. Dusek, L. Taylor-Swanson, H. Tick   +3 more
semanticscholar   +1 more source

Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis.

Anesthesiology, 2020
BACKGROUND Widely used for acute pain management, the clinical benefit from perioperative use of gabapentinoids is uncertain. The aim of this systematic review was to assess the analgesic effect and adverse events with the perioperative use of ...
Michael Verret, F. Lauzier, R. Zarychanski, Caroline Perron, Xavier Savard, A. Pinard, G. Leblanc, Marie-Joëlle Cossi, X. Neveu, A. Turgeon, A. Mcauley, A. Flexman, A. Denault, A. Jerath, Christopher Prabhakar, C. McCartney, C. Sawchuk, Cynthia H. Yarnold, D. Boyle, D. Mazer, David Roach, D. Tran, D. McKeen, D. Yee, D. Wijeysundera, E. Belley‐Cote, E. Jacobsohn, É. de Médicis, F. Carrier, G. Hare, G. Bryson, H. Grocott, Homer Yang, Jason A. McVicar, Jennifer O'Brien, J. Spence, Jim Kim, J. Murkin, Jonathan J. Gamble, K. Sparrow, Kimberley Wong, S. McCluskey, Michael Bautista, M. Law, Michael Schmidt, Nicola Y Edwards, P. Choi, P. Richebé, P. Beaulieu, R. Sondekoppam, R. Arellano, R. Dhawan, Richard Hall, Ron Ree, R. George, Rosaleen Chun, S. Brudney, S. Kowalski, S. Syed, S. Sidhu, Tarit Saha, Thomas C. Mutter, V. Uppal   +62 more
semanticscholar   +1 more source

The Effectiveness of Virtual Reality in Managing Acute Pain and Anxiety for Medical Inpatients: Systematic Review

Journal of Medical Internet Research, 2020
Background Virtual reality is increasingly being utilized by clinicians to facilitate analgesia and anxiolysis within an inpatient setting. There is however, a lack of a clinically relevant review to guide its use for this purpose.
V. Smith, R. Warty, Joel Arun Sursas, O. Payne, Amrish Nair, Sathya Krishnan, F. da Silva Costa, E. Wallace, B. Vollenhoven   +8 more
semanticscholar   +1 more source

Virtual reality distraction for acute pain in children.

Cochrane Database of Systematic Reviews, 2020
BACKGROUND Virtual reality (VR) computer technology creates a simulated environment, perceived as comparable to the real world, with which users can actively interact. The effectiveness of VR distraction on acute pain intensity in children is uncertain.
V. Lambert, Patrick Boylan, Lorraine Boran, Paula Hicks, R. Kirubakaran, D. Devane, A. Matthews   +6 more
semanticscholar   +1 more source

A practical guide to acute pain management in children

Journal of Anesthesia, 2020
In the pediatric population, pain is frequently under-recognized and inadequately treated. Improved education and training of health care providers can positively impact the management of pain in children.
Nan Gai, Basem Naser, J. Hanley, A. Peliowski, J. Hayes, K. Aoyama   +5 more
semanticscholar   +1 more source

Virtual reality for acute pain in outpatient hysteroscopy: a randomised controlled trial

BJOG: an International Journal of Obstetrics and Gynaecology, 2020
To evaluate the effectiveness of virtual reality as a distraction technique in the management of acute pain and anxiety during outpatient hysteroscopy.
N. Deo, Khalid Khan, Jonathan Mak, J. Allotey, Francisoco Jose Gonzalez Carreras, G. Fusari, J. Benn   +6 more
semanticscholar   +1 more source

Acute inflammatory response via neutrophil activation protects against the development of chronic pain

Science Translational Medicine, 2022
The transition from acute to chronic pain is critically important but not well understood. Here, we investigated the pathophysiological mechanisms underlying the transition from acute to chronic low back pain (LBP) and performed transcriptome-wide ...
M. Parisien, L. Lima, C. Dagostino, N. El-Hachem, G. Drury, Audrey V Grant, Jonathan Huising, Vivek Verma, C. B. Meloto, Jaqueline R. Silva, G. M. Dutra, Teodora Markova, H. Dang, P. Tessier, G. Slade, A. Nackley, N. Ghasemlou, J. Mogil, M. Allegri, L. Diatchenko   +19 more
semanticscholar   +1 more source