Results 191 to 200 of about 5,482,047 (410)
ATHENA: A Phase 3, Open-Label Study Of The Safety And Effectiveness Of Oliceridine (TRV130), A G-Protein Selective Agonist At The µ-Opioid Receptor, In Patients With Moderate To Severe Acute Pain Requiring Parenteral Opioid Therapy. [PDF]
Background:Pain management with conventional opioids can be challenging due to dose-limiting adverse events (AEs), some of which may be related to the simultaneous activation of β-arrestin (a signaling pathway associated with opioid-related AEs) and G ...
Beard, Timothy L+10 more
core
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu+7 more
wiley +1 more source
2021 KSCCM clinical practice guidelines for pain, agitation, delirium, immobility, and sleep disturbance in the intensive care unit [PDF]
Yijun Seo+3 more
doaj +1 more source
Acute diffuse muscular pain following initiation of methotrexate therapy. [PDF]
Penelope J. Eames, Anamaria Jones
openalex +1 more source
The addition of calcium ions to silk fibroin enhances the hydrogel properties and, when combined with visible light crosslinking, enables compatibility with advanced light‐based fabrication techniques. Calcium ions extend the shelf‐life of silk and facilitate the fabrication of multizonal, multilayered constructs for advanced stimuli‐responsive ...
Hien A. Tran+11 more
wiley +1 more source
Acute pain is an understudied subject among patients admitted in medical wards, especially in sub-Saharan Africa. Given that it is one of the commonest causes of hospital admissions, it is necessary to diagnose and adequately treat it in time. Unrelieved
Silas Ojuka+2 more
doaj +1 more source
Fibromuscular dysplasia of renal arteries and acute loin pain. [PDF]
Martin Duddy, Sally Bradley, S. Chapman
openalex +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
MAMAWEL is introduced as the first calibration‐free potentiometric sensor for at‐home mastitis diagnosis. By measuring the sodium‐to‐potassium ratio in breast milk, the device reliably differentiates between healthy and mastitis‐affected samples with less than 10% error.
Ali Soleimani+9 more
wiley +1 more source