Results 161 to 170 of about 191,978 (351)

Upadacitinib for difficult‐to‐treat paediatric Crohn's disease

open access: yesJPGN Reports, EarlyView.
Abstract Paediatric‐onset inflammatory bowel disease (IBD) has an enormous impact on healthcare systems as it translates to a lifetime of healthcare. Since the approval of anti‐tumour necrosis factor‐alpha agents, it has become evident that in the long journey of paediatric IBD, there is an absolute need for more treatment options.
N. Nedelkopoulou   +3 more
wiley   +1 more source

Eruptive Xanthomata Manifesting in Tattoos

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Eruptive xanthomata represent a rare, but important pruritic dermatosis for which an accurate diagnosis can prevent life‐threatening complications. We present the case of a 29‐year‐old female with no prior medical history who presented to clinic for evaluation of a pruritic papular eruption of 2 weeks' duration.
Connor Stonesifer   +4 more
wiley   +1 more source

SOAT1 Activates NLRP3 Inflammasome to Promote Cancer‐Related Lymphangiogenesis and Metastasis via IL‐1β/IL‐1R‐1 Axis in Oral Squamous Cell Carcinoma

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Oral squamous cell carcinoma (OSCC) is a prevalent type of cancer in the head and neck region, significantly impacting patient survival rates and quality of life. Lymph node (LN) metastasis is a lead contributor to the poor prognosis associated with OSCC.
Chengzhi Zhao   +6 more
wiley   +1 more source

Acute pancreatitis- a narrative review

open access: yesJournal of the Pakistan Medical Association
Acute pancreatitis is a common cause of acute abdominal pain and can range from mild oedema to severe necrosis of the pancreas. It has a significant impact on morbidity, mortality and financial burden.
Zahabia Sohail   +3 more
doaj   +1 more source

Light‐Activated Pharmacological Tools for Exploring the Cholinergic System

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni   +5 more
wiley   +1 more source

Acute pancreatitis: current perspectives on diagnosis and management

open access: yesJournal of Inflammation Research, 2018
Adarsh P Shah, Moustafa M Mourad, Simon R Bramhall Department of Surgery, Hereford County Hospital, Hereford, UK Abstract: The last two decades have seen the emergence of significant evidence that has altered certain aspects of the management ...
Shah AP, Mourad MM, Bramhall SR
doaj  

The impact of climate change induced natural disasters on healthcare: Rethinking intravenous fluids

open access: yes
Journal of Hospital Medicine, EarlyView.
Elizabeth A. Cerceo   +3 more
wiley   +1 more source

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