Results 1 to 10 of about 553,089 (317)

The SIX1/LDHA Axis Promotes Lactate Accumulation and Leads to NK Cell Dysfunction in Pancreatic Cancer

open access: yesJournal of Immunology Research, 2023
Background. Pancreatic cancer (PC) is a malignant cancer with poor prognosis and high mortality rate. Sine oculis homeobox homolog 1 (SIX1) participates in the development of many cancers.
Wanli Ge   +8 more
doaj   +1 more source

Opposite Roles of Tumor Cell Proliferation and Immune Cell Infiltration in Postoperative Liver Metastasis of PDAC

open access: yesFrontiers in Cell and Developmental Biology, 2021
BackgroundRecurrence of liver metastasis after pancreatectomy is often a predictor of poor prognosis. Comprehensive genomic analysis may contribute to a better understanding of the molecular mechanisms of postoperative liver metastasis and provide new ...
Guangfu Wang   +18 more
doaj   +1 more source

CA9-Related Acidic Microenvironment Mediates CD8+ T Cell Related Immunosuppression in Pancreatic Cancer

open access: yesFrontiers in Oncology, 2022
PurposeThis study aims to integrate pancreatic cancer TCGA, GEO, and single-cell RNA-sequencing (scRNA-seq) datasets, and explore the potential prognostic markers and underlying mechanisms of the immune microenvironment of pancreatic cancer through ...
Lingdi Yin   +33 more
doaj   +1 more source

Pancreas [PDF]

open access: yesAmerican Journal of Transplantation, 2016
Even though pancreas transplant numbers have steadily declined over the past decade, new listings increased in 2014 compared with the previous year, notably for pancreas transplant alone (PTA) and simultaneous pancreas-kidney transplant. The number of new PTAs also increased over the past two years.
R, Kandaswamy   +7 more
openaire   +2 more sources

Establishment and validation of a nomogram based on coagulation parameters to predict the prognosis of pancreatic cancer

open access: yesBMC Cancer, 2023
Background In recent years, multiple coagulation and fibrinolysis (CF) indexes have been reported to be significantly related to the progression and prognosis of some cancers.
Peng Yunpeng   +10 more
doaj   +1 more source

FUS-induced circRHOBTB3 facilitates cell proliferation via miR-600/NACC1 mediated autophagy response in pancreatic ductal adenocarcinoma

open access: yesJournal of Experimental & Clinical Cancer Research, 2021
Background Circular RNAs (circRNAs) are becoming a unique member of non-coding RNAs (ncRNAs) with emerging evidence of their regulatory roles in various cancers.
Taoyue Yang   +13 more
doaj   +1 more source

CircNEIL3 regulatory loop promotes pancreatic ductal adenocarcinoma progression via miRNA sponging and A-to-I RNA-editing

open access: yesMolecular Cancer, 2021
Background A growing number of studies have focused on investigating circRNAs as crucial regulators in the progression of multiple cancer types.
Peng Shen   +13 more
doaj   +1 more source

Extended pancreas donor program - the EXPAND study rationale and study protocol [PDF]

open access: yes, 2013
BACKGROUND: Simultaneous pancreas kidney transplantation (SPK), pancreas transplantation alone (PTA) or pancreas transplantation after kidney (PAK) are the only curative treatment options for patients with type 1 (juvenile) diabetes mellitus with or ...
Bechstein, Wolf Otto   +62 more
core   +1 more source

Long non-coding RNA XLOC_000647 suppresses progression of pancreatic cancer and decreases epithelial-mesenchymal transition-induced cell invasion by down-regulating NLRP3

open access: yesMolecular Cancer, 2018
Background Long non-coding RNAs (lncRNAs) play an important role in the development and progression of various tumors, including pancreatic cancer (PC). Recent studies have shown that lncRNAs can ‘act in cis’ to regulate the expression of its neighboring
Hao Hu   +14 more
doaj   +1 more source

Preganglionic innervation of the pancreas islet cells in the rat [PDF]

open access: yes, 1984
The position and number of preganglionic somata innervating the insulin-secreting β-cells of the endocrine pancreas were investigated in Wistar rats.
Steffens, A.B.,   +14 more
core   +1 more source

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