Results 1 to 10 of about 84,228 (303)

Collision metastasis from prostate adenocarcinoma and pancreatic ductal adenocarcinoma to a lung nodule [PDF]

, 2023
Introduction Prostate cancer and pancreatic cancer are often complex pathologies that affect millions of patients worldwide. However, the incidence of a distant collision metastasis of both malignancies remains a rare and often poorly documented ...
Madaan, S., Saw, S., Mohamed, A., Clark, A., Yao, M.   +4 more
core   +1 more source

Non-coding RNAs in pancreatic ductal adenocarcinoma: New approaches for better diagnosis and therapy [PDF]

, 2021
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies with a 5-year survival rate less than 8%, which has remained unchanged over the last 50 years.
Uysal Onganer, P., Mortoglou, M., Arisan, E.D., Tabin, Z.K., Kocher, H.M.   +4 more
core   +1 more source

How fibrosis influences imaging and surgical decisions in pancreatic cancer

Frontiers in Physiology, 2012
Our understanding of pancreatic ductal adenocarcinoma is shifting away from a disease of malignant ductal cells-only, towards a complex system where tumor evolution is a result of interaction of cancer cells with their microenvironment.
Mert eErkan, Simone eHausmann, Christoph W Michalski, Melissa eSchlitter, Alexander A Fingerle, Martin eDobritz, Helmut eFriess, Jörg eKleeff   +7 more
doaj   +1 more source

Label-free proteomics reveals serum proteins whose levels differ between pancreatic ductal adenocarcinoma patients with short or long survival

Tumor Biology, 2020
Pancreatic ductal adenocarcinoma is the most common and aggressive type of pancreatic cancer, with a 5-year survival rate that is less than 10%. New biomarkers to aid in predicting the prognosis of pancreatic ductal adenocarcinoma patients are needed ...
Matilda Holm, Mayank Saraswat, Sakari Joenväärä, Hanna Seppänen, Risto Renkonen, Caj Haglund   +5 more
doaj   +1 more source

Challenges of drug resistance in the management of pancreatic cancer [PDF]

, 2010
The current treatment of choice for metastatic pancreatic cancer involves single agent gemcitabine or combination of gemcitabine with capecitabine and erlotinib (tyrosine kinase inhibitor).
Naomi Walsh, Martin Clynes, Rizwan Sheikh, Sheikh, Rizwan, O'Connor, Robert A., Robert O’Connor, Ray McDermott, O'Connor, Robert, Clynes, Martin, Walsh, Naomi, McDermott, Ray   +10 more
core   +1 more source

Effect of miR-184 on Proliferation and Apoptosis of Pancreatic Ductal Adenocarcinoma and Its Mechanism

Technology in Cancer Research & Treatment, 2020
Objective: Previous studies have shown that abnormal expression of microRNA-184 leads to a variety of cancers, including pancreatic ductal adenocarcinoma, suggesting microRNA-184 as a new treatment target for pancreatic ductal adenocarcinoma.
Shentao Li MBBS, He Li MD, PhD, Weiwei Ge PhD, Kai Song MM, Chunyu Yuan MM, Ran Yin MBBS   +5 more
doaj   +1 more source

A case report of a collision tumor composed of pancreatic ductal adenocarcinoma and peri-pancreatic mucosa-associated lymphoid tissue lymphoma

World Journal of Surgical Oncology, 2023
Background Collision tumors are composed of two distinct tumor components. Collision tumors composed of pancreatic ductal adenocarcinoma and malignant lymphoma occurring in the pancreas have not been previously described in the scientific literature.
Ryuji Hirai, Ken-ichi Omae, Mitsuko Yodoya, Syunji Fujie, Masayoshi Fujii, Kazuma Iwata, Kentaro Imanishi, Eisuke Kurihara, Kazuhiro Yoshida, Masaru Jida, Kazuyasu Kobayashi, Yoshiaki Kanaya, Syuichiro Maruyama   +12 more
doaj   +1 more source

Hypoxia induces oncogene yes-associated protein 1 nuclear translocation to promote pancreatic ductal adenocarcinoma invasion via epithelial–mesenchymal transition

Tumor Biology, 2017
Pancreatic ductal adenocarcinoma is one of the most lethal cancers. The Hippo pathway is involved in tumorigenesis and remodeling of tumor microenvironments.
Honglong Wei, Zongzhen Xu, Feng Liu, Fuhai Wang, Xin Wang, Xueying Sun, Jie Li   +6 more
doaj   +1 more source

EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells [PDF]

, 2009
The EGF-related protein EFEMP1 (EGF-containing fibulin-like extracellular matrix protein 1) has been shown to promote tumor growth in human adenocarcinoma.
Jauch, Karl-Walter, Krebs, Stefan, Blum, Helmut, Bruns, Christiane J., De Toni, Enrico N., Ischenko, Ivan, Camaj, Peter, Seeliger, Hendrik, Faktorova, Dagmar   +8 more
core   +1 more source

Expression and clinical significance of placenta-specific 1 in pancreatic ductal adenocarcinoma

Tumor Biology, 2017
The limited efficacy of conventional therapies for pancreatic ductal adenocarcinoma has led to the growing interest for identifying potential antigenic targets for immunotherapy.
Yin Yin, Xu Zhu, Shanshan Huang, Jiawei Zheng, Mengyun Zhang, Wencui Kong, Qun Chen, Yan Zhang, Xiong Chen, Kerong Lin, Xuenong Ouyang   +10 more
doaj   +1 more source