Results 31 to 40 of about 433,923 (290)

Nickel's Role in Pancreatic Ductal Adenocarcinoma: Potential Involvement of microRNAs [PDF]

, 2022
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancer types with a limited overall survival rate due to the asymptomatic progression of symptoms in metastatic stages of the malignancy and the lack of an early reliable diagnostic ...
Valle, Elizabeth, Uysal Onganer, P., Manis, Katherine, Mortoglou, M., Buha Djordjevic, A., Bulat, Z., York, Lauren, Đorđević, Vladimir, Wallace, D., Manić, L.   +9 more
core   +1 more source

Macrophages and pancreatic ductal adenocarcinoma [PDF]

Cancer Letters, 2016
Monocytes and macrophages make up part of the innate immune system and provide one of the first defenses against variety of treats. Macrophages can also modulate the adaptive immune system. Efficient sensing and response to tissue environmental cues highlights the complexity and dynamic nature of macrophages and their plasticity.
Habtezion, Aida, Edderkaoui, Mouad, Pandol, Stephen J   +2 more
openaire   +4 more sources

MicroRNA-Regulated Signaling Pathways: Potential Biomarkers for Pancreatic Ductal Adenocarcinoma [PDF]

, 2021
Pancreatic ductal adenocarcinoma (PDAC) is the most aggressive and invasive type of pancreatic cancer (PCa) and is expected to be the second most common cause of cancer-associated deaths.
Uysal Onganer, P., Vladimir Djordjevic, Mortoglou, M., Buha Djordjevic, A., Arisan, E., Wallace, D.   +5 more
core   +1 more source

Immune response and drug therapy based on ac4C-modified gene in pancreatic cancer typing

Frontiers in Immunology, 2023
N-4 cytidine acetylation (ac4C) is an epitranscriptome modification catalyzed by N-acetyltransferase 10 (NAT10) and is essential for cellular mRNA stability, rRNA biosynthesis, cell proliferation, and epithelial-mesenchymal transition (EMT).
Dong Xu, Kaige Huang, Yang Chen, Fei Yang, Cunbing Xia, Hongbao Yang   +5 more
doaj   +1 more source

Cost-effectiveness of diagnostic laparoscopy for assessing resectability in pancreatic and periampullary cancer. [PDF]

, 2015
Surgical resection is the only curative treatment for pancreatic and periampullary cancer, but many patients undergo unnecessary laparotomy because tumours can be understaged by computerised tomography (CT).
Morris, S, Gurusamy, KS, Davidson, BR, Kurinchi S Gurusamy, Stephen Morris, Sheringham, J, Brian R Davidson, Jessica Sheringham   +7 more
core   +2 more sources

Molecular Analysis of Precursor Lesions in Familial Pancreatic Cancer [PDF]

, 2013
PMCID: PMC3553106This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Stipo Jurcevic (276415), Bhakta Vipul, Bronner, Mary, Harada, Tomohiko, Barry Sayka, Bronner, M, Mary Bronner (276416), Lattimore Sam, Lemoine Nicholas R., Tomohiko Harada, Teresa A Brentnall, Crnogorac-Jurcevic, Tatjana, Claude Chelala, Brentnall, TA, Mary Bronner, Sam Lattimore (276414), Lattimore, Sam, Tatjana Crnogorac-Jurcevic (57627), Brentnall, Teresa A, Bhakta, V, Crnogorac-Jurcevic, T, Bronner Mary, Teresa A. Brentnall (186815), Chelala, C, Nicholas R. Lemoine (276417), Jurcevic, Stipo, Barry, Sayka, Brentnall Teresa A., Sam Lattimore, Crnogorac-Jurcevic Tatjana, Lemoine, Nicholas R, Lemoine, NR, Lattimore, S, Jurcevic Stipo, Nicholas R Lemoine, Sayka Barry, Tomohiko Harada (276412), Chelala Claude, Harada, T, Stipo Jurcevic, Barry, S, Vipul Bhakta (276413), Chelala, Claude, Jurcevic, S, Bhakta, Vipul, Vipul Bhakta, Sayka Barry (57623), Tatjana Crnogorac-Jurcevic, Claude Chelala (3016), Harada Tomohiko   +49 more
core   +1 more source

Inhibiting CDK4/6 in pancreatic ductal adenocarcinoma via microRNA-21 [PDF]

, 2023
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies, with a 5-year survival rate of 5–10 %. The high mortality rate is due to the asymptomatic progression of clinical features in metastatic stages of the disease, which ...
Uysal Onganer, P., Miralles, F., Mortoglou, M., Mould, R., Sengupta, D.   +4 more
core   +1 more source

How fibrosis influences imaging and surgical decisions in pancreatic cancer

Frontiers in Physiology, 2012
Our understanding of pancreatic ductal adenocarcinoma is shifting away from a disease of malignant ductal cells-only, towards a complex system where tumor evolution is a result of interaction of cancer cells with their microenvironment.
Mert eErkan, Simone eHausmann, Christoph W Michalski, Melissa eSchlitter, Alexander A Fingerle, Martin eDobritz, Helmut eFriess, Jörg eKleeff   +7 more
doaj   +1 more source

Label-free proteomics reveals serum proteins whose levels differ between pancreatic ductal adenocarcinoma patients with short or long survival

Tumor Biology, 2020
Pancreatic ductal adenocarcinoma is the most common and aggressive type of pancreatic cancer, with a 5-year survival rate that is less than 10%. New biomarkers to aid in predicting the prognosis of pancreatic ductal adenocarcinoma patients are needed ...
Matilda Holm, Mayank Saraswat, Sakari Joenväärä, Hanna Seppänen, Risto Renkonen, Caj Haglund   +5 more
doaj   +1 more source

Effect of miR-184 on Proliferation and Apoptosis of Pancreatic Ductal Adenocarcinoma and Its Mechanism

Technology in Cancer Research & Treatment, 2020
Objective: Previous studies have shown that abnormal expression of microRNA-184 leads to a variety of cancers, including pancreatic ductal adenocarcinoma, suggesting microRNA-184 as a new treatment target for pancreatic ductal adenocarcinoma.
Shentao Li MBBS, He Li MD, PhD, Weiwei Ge PhD, Kai Song MM, Chunyu Yuan MM, Ran Yin MBBS   +5 more
doaj   +1 more source