Results 41 to 50 of about 68,651 (161)
Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability. [PDF]
PLoS ONE, 2017 Pancreatic ductal adenocarcinoma, which accounts for the majority of pancreatic cancers, is a lethal disease with few therapeutic options. Genomic profiling of pancreatic ductal adenocarcinoma has identified a complex and heterogeneous landscape ...
Jeran K Stratford +6 more
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Tumor Biology, 2018 Expression of regenerating islet-derived protein 4 (REG4), a secretory protein involved in cell differentiation and proliferation, is upregulated in inflammatory bowel diseases and in many gastrointestinal malignancies. The prognostic significance of its
Kapo Saukkonen +7 more
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Pictorial Review of Rare Pancreatic Tumors and Tumor-Like Lesions
대한영상의학회지, 2020 Various types of tumors and tumor-like lesions may affect the pancreas. Among them, pancreatic ductal adenocarcinoma is the most common and is generally referred to as “pancreatic cancer.” Recently, the detection rates of rare pancreatic tumors and ...
Seung Jae Lee +3 more
doaj +1 more source
Identification of a novel subpopulation of tumor-initiating cells from gemcitabine-resistant pancreatic ductal adenocarcinoma patients. [PDF]
PLoS ONE, 2013 Pancreatic ductal adenocarcinoma is highly resistant to systemic chemotherapy. Although there are many reports using pancreatic cancer cells derived from patients who did not receive chemotherapy, characteristics of pancreatic cancer cells from ...
Kazuya Shimizu +2 more
doaj +1 more source
Pancreatic Ductal Adenocarcinoma Associated with Autoimmune Pancreatitis [PDF]
Case Reports in Gastroenterology, 2011 Autoimmune pancreatitis (AIP), in contrast to other benign chronic pancreatic diseases, can be cured with immunosuppressant drugs, thus the differentiation of AIP from pancreatic cancer is of particular interest in clinical practice. There is the possibility that some patients with AIP may develop pancreatic cancer, and this possibility contributes to ...
Pezzilli R +9 more
openaire +4 more sources
Antineoplastic effects of auranofin in human pancreatic adenocarcinoma preclinical models
Surgery Open Science, 2019 Background: Auranofin, a Food and Drug Administration–approved anti-rheumatic agent with anticancer properties for lung and ovarian cancer, has never been studied for pancreatic cancer.
Mayrim V. Rios Perez +10 more
doaj +1 more source
The dark side of ferroptosis in pancreatic cancer
OncoImmunology, 2021 Drug-induced ferroptosis, an iron-dependent regulatory necrosis, has been proposed for the therapy of pancreatic ductal adenocarcinoma. However, genetically engineered mouse models have revealed that high-iron diets or deletion of pancreatic GPX4 (a key ...
Jiao Liu +4 more
doaj +1 more source
Mixed pancreatic acinar cell-ductal adenocarcinoma: Complexities in diagnosis and treatment
Current Problems in Cancer: Case Reports, 2022 Background: Acinar cell carcinoma of the pancreas (ACC) is a rare malignancy, accounting for approximately 1-2% of all pancreatic cancers. Up to a quarter of ACCs are estimated to contain a significant component of another histology such as ...
Abdullah Nasser +4 more
doaj +1 more source
Risk of pancreatic ductal adenocarcinoma in chronic pancreatitis [PDF]
Gut, 2002 Patients with chronic pancreatitis have a markedly increased risk of pancreatic cancer compared with the general population Chronic pancreatitis has been proposed as an independent risk factor for the development of pancreatic cancer in a number of important studies.1–3 Problems with methodology however, such as patient selection, ascertainment bias ...
N, Howes, J P, Neoptolemos
openaire +2 more sources
Acta Medica, 2003 Aim: To determine the immunoreactivity of pancreatic-polypeptide (PP) during the development of the human fetal pancreas and ductal pancreatic adenocarcinoma, given that, PP positive cells were demonstrated either into its embryonic anlage or into ...
Demetrio Tamiolakis +5 more
doaj +1 more source