Results 41 to 50 of about 433,923 (290)

Hypoxia induces oncogene yes-associated protein 1 nuclear translocation to promote pancreatic ductal adenocarcinoma invasion via epithelial–mesenchymal transition

Tumor Biology, 2017
Pancreatic ductal adenocarcinoma is one of the most lethal cancers. The Hippo pathway is involved in tumorigenesis and remodeling of tumor microenvironments.
Honglong Wei, Zongzhen Xu, Feng Liu, Fuhai Wang, Xin Wang, Xueying Sun, Jie Li   +6 more
doaj   +1 more source

A case report of a collision tumor composed of pancreatic ductal adenocarcinoma and peri-pancreatic mucosa-associated lymphoid tissue lymphoma

World Journal of Surgical Oncology, 2023
Background Collision tumors are composed of two distinct tumor components. Collision tumors composed of pancreatic ductal adenocarcinoma and malignant lymphoma occurring in the pancreas have not been previously described in the scientific literature.
Ryuji Hirai, Ken-ichi Omae, Mitsuko Yodoya, Syunji Fujie, Masayoshi Fujii, Kazuma Iwata, Kentaro Imanishi, Eisuke Kurihara, Kazuhiro Yoshida, Masaru Jida, Kazuyasu Kobayashi, Yoshiaki Kanaya, Syuichiro Maruyama   +12 more
doaj   +1 more source

Expression and clinical significance of placenta-specific 1 in pancreatic ductal adenocarcinoma

Tumor Biology, 2017
The limited efficacy of conventional therapies for pancreatic ductal adenocarcinoma has led to the growing interest for identifying potential antigenic targets for immunotherapy.
Yin Yin, Xu Zhu, Shanshan Huang, Jiawei Zheng, Mengyun Zhang, Wencui Kong, Qun Chen, Yan Zhang, Xiong Chen, Kerong Lin, Xuenong Ouyang   +10 more
doaj   +1 more source

Imaging for pancreatic ductal adenocarcinoma

Chinese Clinical Oncology, 2017
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers worldwide due to its aggressiveness and the challenge to early diagnosis. Complete surgical resection is the only curative option, but fewer than 20% of patients have potentially resectable disease at the time of the diagnosis.
Natally, Horvat, Davinia E, Ryan, Maria D, LaGratta, Pari M, Shah, Richard Kinh, Do   +4 more
openaire   +2 more sources

H+ és HCO3- transzporterek szabályozása humán pancreas ductus sejtekben = Regulation of H+ and HCO3-Transporters in Human Pancreatic Duct Cells [PDF]

, 2009
A pancreas nedvben található HCO3- ionok kiválasztásáért a pancreas ductus sejtek felelősek. Jelen pályázatban célul tűztük ki, hogy molekuláris biológiai, transzdukciós és mikrofluorescens technikák felhasználásával megértsük a HCO3- szekréció ...
Rakonczay, Zoltán
core   +1 more source

Role of artificial intelligence and novel visualization techniques in the early diagnosis of pancreatic cancer: a review

Digital Diagnostics
Pancreatic ductal adenocarcinoma is the most common pancreatic cancer. It is characterized by a progressive course or distant metastases in 80%–85% of cases.
Ferida T. Musaeva, Elizaveta R. Sumenova, Almaz Kh. Islamgulov, Zalina M. Kumykova, Tamila S. Elipkhanova, Alina I. Ushaeva, Amina S. Khasieva, Ekaterina S. Ozerova, Dina A. Khusnutdinova, Alina A. Nabiullina, Yana Yu. Kulinskaya, Roksana R. Yakupova, Arthur A. Mustafin   +12 more
doaj   +1 more source

Challenges of drug resistance in the management of pancreatic cancer [PDF]

, 2010
The current treatment of choice for metastatic pancreatic cancer involves single agent gemcitabine or combination of gemcitabine with capecitabine and erlotinib (tyrosine kinase inhibitor).
Naomi Walsh, Martin Clynes, Rizwan Sheikh, Sheikh, Rizwan, O'Connor, Robert A., Robert O’Connor, Ray McDermott, O'Connor, Robert, Clynes, Martin, Walsh, Naomi, McDermott, Ray   +10 more
core   +1 more source

EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells [PDF]

, 2009
The EGF-related protein EFEMP1 (EGF-containing fibulin-like extracellular matrix protein 1) has been shown to promote tumor growth in human adenocarcinoma.
Jauch, Karl-Walter, Krebs, Stefan, Blum, Helmut, Bruns, Christiane J., De Toni, Enrico N., Ischenko, Ivan, Camaj, Peter, Seeliger, Hendrik, Faktorova, Dagmar   +8 more
core   +1 more source

MiR-590 Suppresses Proliferation and Induces Apoptosis in Pancreatic Cancer by Targeting High Mobility Group A2

Technology in Cancer Research & Treatment, 2020
Background: Pancreatic ductal adenocarcinoma is a common malignancy with high morbidity. MicroRNAs have been demonstrated to be critical posttranscriptional regulators in tumorigenesis.
Ya-Dong Wang MD, Jia-Ding Mao PhD, Jun-Feng Wang MD, Mao-Qi Xu MD   +3 more
doaj   +1 more source

Comparative Analysis of Primary and Liver Fibroblasts Reveals MET as a Potent Target in Pancreatic Cancer Metastasis

Cellular and Molecular Gastroenterology and Hepatology
Background & Aims: :The tumor microenvironment drives many malignant features of pancreatic ductal adenocarcinoma. The fibroblasts within pancreatic tumors promote tissue remodeling, immune suppression, and resistance to therapy.
Rima Singh, Natalie Yousefian, Walker M. Allen, Austin D. Silva, Cecily Anaraki, Alica K. Michels, Sabrina Calderon, Ian M. Loveless, Daniella Rastelli, Ashley George, Mohammed Aldakkak, Oliver G. McDonald, Nikki K. Lytle, Jennifer P. Morton, Reed I. Ayabe, David Imagawa, Zeljka Jutric, Thomas F. Martinez, Nina G. Steele, Christopher J. Halbrook   +19 more
doaj   +1 more source