Results 21 to 30 of about 68,651 (161)
Immune response and drug therapy based on ac4C-modified gene in pancreatic cancer typing
Frontiers in Immunology, 2023 N-4 cytidine acetylation (ac4C) is an epitranscriptome modification catalyzed by N-acetyltransferase 10 (NAT10) and is essential for cellular mRNA stability, rRNA biosynthesis, cell proliferation, and epithelial-mesenchymal transition (EMT).
Dong Xu +5 more
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Macrophages and pancreatic ductal adenocarcinoma [PDF]
Cancer Letters, 2016 Monocytes and macrophages make up part of the innate immune system and provide one of the first defenses against variety of treats. Macrophages can also modulate the adaptive immune system. Efficient sensing and response to tissue environmental cues highlights the complexity and dynamic nature of macrophages and their plasticity.
Habtezion, Aida +2 more
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How fibrosis influences imaging and surgical decisions in pancreatic cancer
Frontiers in Physiology, 2012 Our understanding of pancreatic ductal adenocarcinoma is shifting away from a disease of malignant ductal cells-only, towards a complex system where tumor evolution is a result of interaction of cancer cells with their microenvironment.
Mert eErkan +7 more
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MicroRNAs in pancreatic ductal adenocarcinoma
World Journal of Gastroenterology, 2011 Ductal adenocarcinoma of the pancreas is a lethal cancer for which the only chance of long-term survival belongs to the patient with localized disease in whom a potentially curative resection can be done. Therefore, biomarkers for early detection and new therapeutic strategies are urgently needed.
Jong Y, Park +5 more
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Tumor Biology, 2020 Pancreatic ductal adenocarcinoma is the most common and aggressive type of pancreatic cancer, with a 5-year survival rate that is less than 10%. New biomarkers to aid in predicting the prognosis of pancreatic ductal adenocarcinoma patients are needed ...
Matilda Holm +5 more
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Technology in Cancer Research & Treatment, 2020 Objective: Previous studies have shown that abnormal expression of microRNA-184 leads to a variety of cancers, including pancreatic ductal adenocarcinoma, suggesting microRNA-184 as a new treatment target for pancreatic ductal adenocarcinoma.
Shentao Li MBBS +5 more
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World Journal of Surgical Oncology, 2023 Background Collision tumors are composed of two distinct tumor components. Collision tumors composed of pancreatic ductal adenocarcinoma and malignant lymphoma occurring in the pancreas have not been previously described in the scientific literature.
Ryuji Hirai +12 more
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Pancreatic Ductal Adenocarcinoma [PDF]
The American Journal of Pathology, 2019 Pancreatic ductal adenocarcinoma represents the most common malignant tumor of the pancreas. Despite substantial research efforts and gradual diagnostic and therapeutic improvements, its prognosis remains dismal. In accordance with the current German, European, and US guidelines, this CME-article provides a comprehensive review of the disease.
E, Gallmeier, T M, Gress
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Tumor Biology, 2017 Pancreatic ductal adenocarcinoma is one of the most lethal cancers. The Hippo pathway is involved in tumorigenesis and remodeling of tumor microenvironments.
Honglong Wei +6 more
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Imaging for pancreatic ductal adenocarcinoma
Chinese Clinical Oncology, 2017 Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers worldwide due to its aggressiveness and the challenge to early diagnosis. Complete surgical resection is the only curative option, but fewer than 20% of patients have potentially resectable disease at the time of the diagnosis.
Natally, Horvat +4 more
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