Results 11 to 20 of about 68,651 (161)
Models of pancreatic ductal adenocarcinoma [PDF]
Cancer and Metastasis Reviews, 2021 AbstractAlthough pancreatic cancer remains to be a leading cause of cancer-related deaths in many industrialized countries, there have been major advances in research over the past two decades that provided a detailed insight into the molecular and developmental processes that govern the genesis of this highly malignant tumor type.
Rayane Dennaoui +2 more
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Ductal Pancreatic Adenocarcinoma [PDF]
Deutsches Ärzteblatt international, 2014 Ductal adenocarcinoma of the pancreas is the fourth most common cause of death from cancer in men and women in Germany: about 15 000 persons die of this disease each year.The S3 guideline on exocrine pancreatic carcinoma was updated with the aid of systematic literature reviews on the surgical, neoadjuvant, and adjuvant treatment of ductal pancreatic ...
Seufferlein, Thomas +5 more
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Pancreatic Ductal Adenocarcinoma [PDF]
Mayo Clinic Proceedings, 2017 Pancreatic ductal adenocarcinoma is ranked fourth in cancer-causing deaths. Most cases of pancreatic cancer are advanced and unresectable at the time of diagnosis due to their delayed symptomatic presentation. PET/MR imaging has a high sensitivity and specificity for detecting malignant pancreatic lesions and provides superior soft tissue detail to ...
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Carcinogenesis of Pancreatic Ductal Adenocarcinoma [PDF]
Gastroenterology, 2020 Although the estimated time for development of pancreatic ductal adenocarcinoma (PDA) is more than 20 years, PDAs are usually detected at late, metastatic stages. PDAs develop from duct-like cells through a multistep carcinogenesis process, from low-grade dysplastic lesions to carcinoma in situ and eventually to metastatic disease.
Peter, Storz, Howard C, Crawford
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Pancreatic Ductal Adenocarcinoma [PDF]
, 2020 The most frequent indication for pancreatic fine-needle aspiration sampling is to confirm or exclude a pancreatic ductal adenocarcinoma (PDAC). PDAC is the most common malignant neoplasm of the pancreas, and the term pancreatic cancer typically connotes this entity.
Jasreman, Dhillon, Michel, Betancourt
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Pancreatic ductal adenocarcinoma staging [PDF]
Cancer Imaging, 2013 In addition to clinical history and evaluations, the results of laboratory tests and imaging studies help clinicians in determining treatment strategies. Imaging plays a central role in the management of oncology patients including the initial diagnosis, staging, and follow-up to assess treatment response. Historically, radiologists have relied on free-
Al-Hawary, Mahmoud M., Francis, Isaac R.
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An Immunological Glance on Pancreatic Ductal Adenocarcinoma [PDF]
International Journal of Molecular Sciences, 2020 Pancreatic ductal adenocarcinoma (PDAC) has still a dismal prognosis. Different factors such as mutational landscape, intra- and intertumoral heterogeneity, stroma, and immune cells impact carcinogenesis of PDAC associated with an immunosuppressive microenvironment. Different cell types with partly opposing roles contribute to this milieu.
Michael Karl Melzer +7 more
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Familial Pancreatic Ductal Adenocarcinoma [PDF]
The American Journal of Pathology, 2019 Pancreatic ductal adenocarcinoma (PDAC), although a rare disease, has a poor prognosis. With 5-year overall survival of 8%, there is a critical need to detect PDAC early or at a premalignant stage. Current screening methods are largely imaging based, but a more focused screening approach based on modifiable and nonmodifiable risk factors may improve ...
Kelly E, Diaz, Aimee L, Lucas
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Mimics of pancreatic ductal adenocarcinoma [PDF]
Cancer Imaging, 2013 Several uncommon primary pancreatic tumors, inflammatory conditions, metastasis to the pancreas and peripancreatic masses can mimic the appearance of pancreatic ductal adenocarcinoma (PDA). Differentiation between these lesions and PDA can be challenging, due to the overlap in imaging features; however, familiarity with their typical imaging features ...
Al-Hawary, Mahmoud M. +4 more
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Desmoplasia of Pancreatic Ductal Adenocarcinoma [PDF]
Clinical Gastroenterology and Hepatology, 2009 Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer and is characterized by remarkable desmoplasia. The desmoplasia is composed of extracellular matrix (ECM) proteins, myofibroblastic pancreatic stellate cells, and immune cells associated with a multitude of cytokines, growth factors, and ECM metabolizing enzymes.
Stephen, Pandol +4 more
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