Results 1 to 10 of about 54,977 (304)

Multitasking dynamic contrast enhanced magnetic resonance imaging can accurately differentiate chronic pancreatitis from pancreatic ductal adenocarcinoma

Frontiers in Oncology, 2023
Background and aimsAccurate differentiation of chronic pancreatitis (CP) and pancreatic ductal adenocarcinoma (PDAC) is an area of unmet clinical need.
Nan Wang, Srinivas Gaddam, Yibin Xie, Anthony G. Christodoulou, Anthony G. Christodoulou, Chaowei Wu, Chaowei Wu, Sen Ma, Zhaoyang Fan, Zhaoyang Fan, Lixia Wang, Simon Lo, Andrew E. Hendifar, Stephen J. Pandol, Debiao Li, Debiao Li   +15 more
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Enhanced release of ciliary extracellular vesicles suppresses cell migration and promotes cell aggregation

Cell Structure and Function
A primary cilium is a hair-like organelle that protrudes from the cell surface in many cell types. Growing evidence indicates that extracellular vesicles are released from primary cilia, and research is increasingly focused on defining the functions of ...
Tetsuhiro Hara, Ryota Nakazato, Kenji Shirakawa, Faryal Ijaz, Kenichiro Uemura, Shinya Takahashi, Koji Ikegami   +6 more
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Microbiome in pancreatic cancer – What is new in 2024? [PDF]

Microbiota in Health and Disease
Despite great efforts to improve understanding and treatment of pancreatic cancer, mainly pancreatic ductal adenocarcinoma (PDAC), the outcome of this malignant disease today is still very poor.
E. Hohmann, C. Ammer-Herrmenau, C. Schulz, S. Sirtl   +3 more
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Integrated analysis revealed hypoxia signatures and LDHA related to tumor cell dedifferentiation and unfavorable prognosis in pancreatic adenocarcinoma

Translational Oncology, 2023
Pancreatic ductal adenocarcinoma (PDAC) is a highly heterogeneous cancer with limited understanding of its classification and tumor microenvironment.
Mingwei Dong, Rong Tang, Wei Wang, Jin Xu, Jiang Liu, Chen Liang, Jie Hua, Qingcai Meng, Xianjun Yu, Bo Zhang, Si Shi   +10 more
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Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p

Cancer Management and Research, 2020
Weisheng Guo,1 Lin Zhao,1 Guangya Wei,1 Peng Liu,1 Yu Zhang,1 Liran Fu2 1Department of Hepatobiliary Surgery, Henan Province Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine ...
Guo W, Zhao L, Wei G, Liu P, Zhang Y, Fu L   +5 more
doaj  

Clinical features and prognostic impact of asymptomatic pancreatic cancer

Scientific Reports, 2022
Pancreatic ductal adenocarcinoma (PDAC) is highly lethal, and early diagnosis is challenging. Because patients who present with symptoms generally have advanced-stage diseases, analysis of asymptomatic PDAC provides invaluable information for developing ...
Tetsuya Takikawa, Kazuhiro Kikuta, Shin Hamada, Kiyoshi Kume, Shin Miura, Naoki Yoshida, Yu Tanaka, Ryotaro Matsumoto, Mio Ikeda, Fumiya Kataoka, Akira Sasaki, Kei Nakagawa, Michiaki Unno, Atsushi Masamune   +13 more
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Combination of serum human satellite RNA and miR-21-5p levels as a biomarker for pancreatic cancer

iScience, 2023
Summary: Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis due to the difficulty of its diagnosis. Because human satellite II (HSATII) RNA, a satellite repeat RNA, is highly and specifically expressed in human PDAC, the serum HSATII RNA level ...
Takahiro Seimiya, Tatsunori Suzuki, Takuma Iwata, Takahiro Kishikawa, Kazuma Sekiba, Chikako Shibata, Kazunaga Ishigaki, Hiroaki Fujiwara, Hiroki Oyama, Sachiko Kanai, Tatsuya Sato, Yousuke Nakai, Rei Ishibashi, Masaru Moriyama, Ryo Nakagawa, Hideaki Ijichi, Motoyuki Otsuka, Kazuhiko Koike   +17 more
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Impact of comprehensive family history and genetic analysis in the multidisciplinary pancreatic tumor clinic setting

Cancer Medicine, 2023
Background Genetic testing is recommended for all pancreatic ductal adenocarcinoma (PDAC) patients. Prior research demonstrates that multidisciplinary pancreatic cancer clinics (MDPCs) improve treatment‐ and survival‐related outcomes for PDAC patients ...
Jessica N. Everett, Shenin A. Sanoba, Xiaohong Jing, Cody Stender, Madeleine Schmitter, Ariele Baptiste, Jennifer Chun, Emily A. Kawaler, Lauren G. Khanna, Seth A. Gross, Tamas A. Gonda, Nina Beri, Paul E. Oberstein, Diane M. Simeone   +13 more
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MiR-429 Determines Poor Outcome and Inhibits Pancreatic Ductal Adenocarcinoma Growth by Targeting TBK1

Cellular Physiology and Biochemistry, 2015
Background: Pancreatic ductal adenocarcinoma (PDAC) ranks fourth on the list of cancer-related causes of death and its prognosis has not improved significantly over the past decades. Deregulation or dysfunction of miRNAs contribute to cancer development.
Bin Song, Kailian Zheng, Hongyun Ma, Anan Liu, Wei Jing, Chenghao Shao, Gang Li, Gang Jin   +7 more
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Ferroptosis: New Strategies and Ideas for the Treatment of Pancreatic Ductal Adenocarcinoma

Frontiers in Bioscience-Landmark
Pancreatic cancer is a malignancy that affects the digestive tract and has a low 5-year survival rate of lower than 15%. Owing to its genetic mutation and metabolic complexity, pancreatic cancer is difficult to treat with surgical resection, radiotherapy,
Chengru Yang, Qingfu Dong, Haolin Bao, Yifei Ge, Zhaoqiang Xu, Jinglin Li, Xingming Jiang, Yi Xu, Xiangyu Zhong   +8 more
doaj   +1 more source