Results 1 to 10 of about 1,169,425 (315)

The invasive cactus Opuntia stricta creates fertility islands in African savannas and benefits from those created by native trees

Scientific Reports, 2021
The patchy distribution of trees typical of savannas often results in a discontinuous distribution of water, nutrient resources, and microbial communities in soil, commonly referred to as “islands of fertility”. We assessed how this phenomenon may affect
Ana Novoa, Llewellyn C. Foxcroft, Jan-Hendrik Keet, Petr Pyšek, Johannes J. Le Roux   +4 more
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Protein dynamics at invadopodia control invasion–migration transitions in melanoma cells

Cell Death and Disease, 2023
Cell invasion is a highly complex process that requires the coordination of cell migration and degradation of the extracellular matrix. In melanoma cells, as in many highly invasive cancer cell types these processes are driven by the regulated formation ...
Marlène Legrand, Antoine Mousson, Philippe Carl, Léa Rossé, Hélène Justiniano, Jean-Pierre Gies, Daniel Bouvard, Emilie Sick, Denis Dujardin, Philippe Rondé   +9 more
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Albumin-to-alkaline phosphatase ratio as a predictor of tumor recurrence and prognosis in patients with early-stage hepatocellular carcinoma undergoing radiofrequency ablation as initial therapy

International Journal of Hyperthermia, 2021
Objective Albumin-to-alkaline phosphatase ratio (AAPR), a newly developed blood biomarker, has been reported to have prognostic value in several types of cancer.
Feng Zhang, Shen-Xin Lu, Ke-Shu Hu, Yu-Hong Gan, Yi Chen, Ning-Lin Ge, Bi-Wei Yang, Lan Zhang, Rong-Xin Chen, Zheng-Gang Ren, Xin Yin   +10 more
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To South Africa and beyond: Local distribution and global invasion potential of the alien anemone Cereus pedunculatus [PDF]

Aquatic Invasions
Effective management of invasive alien species relies on spatial and temporal data. Yet, such information is scarce in the marine realm due to challenges associated with monitoring in highly connected environments that can be difficult to observe.
Miranda N. Andersen, Geethen Singh, Tamara B. Robinson   +2 more
doaj   +3 more sources

M2-polarized tumor-associated macrophages facilitated migration and epithelial-mesenchymal transition of HCC cells via the TLR4/STAT3 signaling pathway

World Journal of Surgical Oncology, 2018
Background M2-polarized macrophages are tumor-associated-macrophages (TAMs), which are important contents of tumor-infiltrating immune cells. Toll-like receptor 4 (TLR4) is a molecular biomarker of tumor aggressiveness and poor prognosis.
Rong-Rong Yao, Jing-Huan Li, Rui Zhang, Rong-Xin Chen, Yan-Hong Wang   +4 more
doaj   +1 more source

Managing conflict-generating invasive species in South Africa: Challenges and trade-offs

Bothalia: African Biodiversity & Conservation, 2017
Background: This paper reviewed the benefits and negative impacts of alien species that are currently listed in the Alien and Invasive Species Regulations of the National Environmental Management: Biodiversity Act (Act no 10 of 2004) and certain alien ...
Tsungai Zengeya, Philip Ivey, Darragh J. Woodford, Olaf Weyl, Ana Novoa, Ross Shackleton, David Richardson, Brian van Wilgen   +7 more
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Integrin alpha-2 and beta-1 expression increases through multiple generations of the EDW01 patient-derived xenograft model of breast cancer—insight into their role in epithelial mesenchymal transition in vivo gained from an in vitro model system

Breast Cancer Research, 2020
Background Breast cancers acquire aggressive capabilities via epithelial to mesenchymal transition (EMT), in which various integrins/integrin-linked kinase signalling are upregulated.
Razan Wafai, Elizabeth D. Williams, Emma de Souza, Peter T. Simpson, Amy E. McCart Reed, Jamie R. Kutasovic, Mark Waltham, Cameron E. Snell, Tony Blick, Erik W. Thompson, Honor J. Hugo   +10 more
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Effects of mesenchymal stem cells on solid tumor metastasis in experimental cancer models: a systematic review and meta-analysis

Journal of Translational Medicine, 2018
Background It has been reported mesenchymal stem cells (MSCs) are recruited to and become integral parts of the tumor microenvironment. MSCs might have an active role in solid tumor progression, especially cancer metastasis.
Jing-Huan Li, Wen-Shuai Fan, Mi-Mi Wang, Yan-Hong Wang, Zheng-Gang Ren   +4 more
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GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation sensitizer

Signal Transduction and Targeted Therapy, 2023
In the treatment of most malignancies, radiotherapy plays a significant role. However, the resistance of cancer cells to ionizing radiation (IR) is the main reason for the failure of radiotherapy, which causes tumor recurrence and metastasis.
Yao Long, Jiaxing Guo, Jielin Chen, Jingyue Sun, Haiyan Wang, Xin Peng, Zuli Wang, WeiWei Lai, Na Liu, Long Shu, Ling Chen, Ying Shi, Desheng Xiao, Shuang Liu, Yongguang Tao   +14 more
doaj   +1 more source

Norepinephrine-stimulated HSCs secrete sFRP1 to promote HCC progression following chronic stress via augmentation of a Wnt16B/β-catenin positive feedback loop

Journal of Experimental & Clinical Cancer Research, 2020
Background Sustained adrenergic signaling secondary to chronic stress promotes cancer progression; however, the underlying mechanisms for this phenomenon remain unclear.
Xia-Hui Lin, Hua-Hua Liu, Shu-Jung Hsu, Rui Zhang, Jie Chen, Jun Chen, Dong-Mei Gao, Jie-Feng Cui, Zheng-Gang Ren, Rong-Xin Chen   +9 more
doaj   +1 more source